
<p>Get to the heart of pain relief </p><p><em>Explain why analgesic choice matters to patients with, or at risk for, cardiovascular disease </em></p><p></p><ul style="display: flex;"><li style="flex:1">|</li><li style="flex:1">|</li></ul><p></p><ul style="display: flex;"><li style="flex:1">Counseling tips </li><li style="flex:1">Dosage </li><li style="flex:1">Savings </li></ul><p></p><p>Analgesic considerations that matter to the heart </p><p>®</p><p>Reinforce your TYLENOL recommendation to patients with, or at risk for, cardiovascular disease with these counseling tips: </p><p><strong>TYLENOL</strong><sup style="top: -0.2497em;"><strong>® </strong></sup><strong>won’t increase the risk of heart attack, heart failure, or stroke </strong>the way ibuprofen </p><p>or naproxen sodium can<sup style="top: -0.2497em;">1 </sup></p><p><strong>TYLENOL</strong><sup style="top: -0.2498em;"><strong>® </strong></sup><strong>won’t interfere with aspirin heart therapy </strong>the way ibuprofen can<sup style="top: -0.2498em;">2 </sup></p><p><strong>TYLENOL</strong><sup style="top: -0.2498em;"><strong>® </strong></sup><strong>won’t increase blood pressure </strong></p><p>like NSAIDs sometimes can<sup style="top: -0.2497em;">3,4 </sup></p><p><strong>TYLENOL</strong><sup style="top: -0.2497em;"><strong>® </strong></sup><strong>won’t interfere with certain high blood pressure medications, such as diuretics and ACE inhibitors, </strong>the way NSAIDs sometimes can<sup style="top: -0.2497em;">3,4 </sup></p><p><em>Order patient education, samples, and coupons at </em></p><p>TylenolProfessional.com </p><p><strong>Not a member? </strong>Register today! </p><p>The efficacy and safety of TYLENOL<sup style="top: -0.2498em;">® </sup>at 4000 mg/day are well established. Healthcare professionals may exercise their discretion and recommend up to 4000 mg. </p><p>Dosage for Adults </p><p></p><ul style="display: flex;"><li style="flex:1">Recommended dose from your healthcare professional: </li><li style="flex:1">mg/day </li></ul><p></p><p><strong>TYLENOL</strong><sup style="top: -0.2775em;"><strong>® </strong></sup><strong>Regular Strength </strong></p><p>Active ingredient: acetaminophen 325 mg (per tablet) </p><p>Use only as directed. </p><p></p><ul style="display: flex;"><li style="flex:1"><strong>DOSE & FREQUENCY </strong></li><li style="flex:1"><strong>DAILY LIMIT </strong></li></ul><p></p><p></p><ul style="display: flex;"><li style="flex:1"><strong>2 tablets every 4 to 6 hours </strong></li><li style="flex:1"><strong>Do not take more than 10 tablets </strong></li></ul><p></p><p></p><ul style="display: flex;"><li style="flex:1">while symptoms last </li><li style="flex:1"><strong>in 24 hours, </strong>unless directed by your doctor </li></ul><p></p><p><strong>TYLENOL</strong><sup style="top: -0.2775em;"><strong>® </strong></sup><strong>Extra Strength </strong></p><p>Active ingredient: acetaminophen 500 mg (per caplet) </p><p>Use only as directed. </p><p></p><ul style="display: flex;"><li style="flex:1"><strong>DOSE & FREQUENCY </strong></li><li style="flex:1"><strong>DAILY LIMIT </strong></li></ul><p></p><p></p><ul style="display: flex;"><li style="flex:1"><strong>2 caplets every 6 hours </strong>while </li><li style="flex:1"><strong>Do not take more than 6 caplets </strong></li></ul><p></p><p></p><ul style="display: flex;"><li style="flex:1">symptoms last </li><li style="flex:1"><strong>in 24 hours, </strong>unless directed by your doctor </li></ul><p></p><p><strong>TYLENOL</strong><sup style="top: -0.2775em;"><strong>® </strong></sup><strong>8 HR Arthritis Pain </strong></p><p>Active ingredient: acetaminophen 650 mg (per extended-release caplet) </p><p>Use only as directed. </p><p></p><ul style="display: flex;"><li style="flex:1"><strong>DOSE & FREQUENCY </strong></li><li style="flex:1"><strong>DAILY LIMIT </strong></li></ul><p></p><p><strong>Do not take more than 6 bi-layer caplets in 24 hours </strong><br><strong>2 bi-layer caplets every 8 hours </strong>with water </p><p><strong>TYLENOL</strong><sup style="top: -0.2498em;"><strong>® </strong></sup><strong>is the #1 doctor recommended brand of pain reliever for those with high blood pressure. </strong></p><p><em>See heart health pain reliever tips </em></p><p></p><p>TYLENOL<sup style="top: -0.5272em;">® </sup>works differently than other pain relievers </p><p>TYLENOL<sup style="top: -0.2498em;">® </sup>(acetaminophen) works differently than MOTRIN<sup style="top: -0.2498em;">® </sup>IB and <br>Advil<sup style="top: -0.2498em;">® </sup>(ibuprofen), Aleve<sup style="top: -0.2498em;">® </sup>(naproxen sodium), and aspirin, which are all NSAIDs.<sup style="top: -0.2498em;">* </sup></p><p><strong>TYLENOL</strong><sup style="top: -0.2081em;"><strong>® </strong></sup><strong>won’t increase your risk of heart attack, heart failure, or stroke </strong>the </p><p>way ibuprofen or naproxen sodium can </p><p><strong>TYLENOL</strong><sup style="top: -0.2081em;"><strong>® </strong></sup><strong>won’t increase your blood pressure </strong>like NSAIDs sometimes can </p><p><strong>TYLENOL</strong><sup style="top: -0.2081em;"><strong>® </strong></sup><strong>won’t interfere with certain high blood pressure medications </strong>the </p><p>way NSAIDs sometimes can </p><p><strong>TYLENOL</strong><sup style="top: -0.2081em;"><strong>® </strong></sup><strong>doesn’t interfere with aspirin heart therapy </strong>the way ibuprofen can </p><p>Check your medicines </p><p>Always read and follow the label, and take only one medicine that contains the same kind of active ingredient at a time. This may help reduce your risk of harmful side effects. </p><p>Medicine brands with products that contain <strong>acetaminophen </strong></p><p></p><ul style="display: flex;"><li style="flex:1"><strong>Over-the-counter (OTC) </strong></li><li style="flex:1"><strong>Prescription </strong></li></ul><p></p><p></p><ul style="display: flex;"><li style="flex:1">Alka-Seltzer Plus<sup style="top: -0.2081em;">® </sup></li><li style="flex:1">NyQuil<sup style="top: -0.2081em;">® </sup></li><li style="flex:1">Endocet<sup style="top: -0.2081em;">® </sup></li></ul><p>Fioricet<sup style="top: -0.2081em;">® </sup>Lortab<sup style="top: -0.2081em;">® </sup><br>Roxicet<sup style="top: -0.2081em;">™ </sup><br>DayQuil<sup style="top: -0.2081em;">® </sup>Excedrin<sup style="top: -0.2081em;">® </sup>Goody’s<sup style="top: -0.2081em;">® </sup>Mucinex<sup style="top: -0.2081em;">® </sup><br>Pamprin<sup style="top: -0.2081em;">® </sup>Robitussin<sup style="top: -0.2081em;">® </sup></p><p>SUDAFED<sup style="top: -0.2081em;">® </sup>TYLENOL<sup style="top: -0.2081em;">® </sup></p><p>Ultracet<sup style="top: -0.2081em;">® </sup>Vicodin<sup style="top: -0.2081em;">® </sup></p><p>®</p><p></p><ul style="display: flex;"><li style="flex:1">Norco<sup style="top: -0.2081em;">® </sup></li><li style="flex:1">TYLENOL with Codeine </li></ul><p>Percocet<sup style="top: -0.2081em;">® </sup></p><p>Medicine brands with products that contain an <strong>NSAID </strong></p><p><strong>Over-the-counter (OTC) Prescription </strong></p><p></p><ul style="display: flex;"><li style="flex:1">Advil<sup style="top: -0.2081em;">® </sup></li><li style="flex:1">Excedrin<sup style="top: -0.2081em;">® </sup></li><li style="flex:1">Celebrex<sup style="top: -0.2081em;">® </sup></li></ul><p>Ibuprofen Inocin<sup style="top: -0.2081em;">® </sup>Lodine<sup style="top: -0.2081em;">® </sup>Mobic<sup style="top: -0.2081em;">® </sup><br>Naproxen </p><ul style="display: flex;"><li style="flex:1">Relafen<sup style="top: -0.2081em;">® </sup></li><li style="flex:1">Aleve<sup style="top: -0.2081em;">® </sup></li><li style="flex:1">Goody’s<sup style="top: -0.2081em;">® </sup></li></ul><p></p><ul style="display: flex;"><li style="flex:1">Midol<sup style="top: -0.2081em;">® </sup></li><li style="flex:1">Alka-Seltzer Plus<sup style="top: -0.2081em;">® </sup></li></ul><p>Anacin<sup style="top: -0.2081em;">® </sup>Bayer<sup style="top: -0.2081em;">® </sup><br>Toradol<sup style="top: -0.2081em;">® </sup><br>MOTRIN<sup style="top: -0.2081em;">® </sup>Sudafed<sup style="top: -0.2081em;">® </sup><br>Vicoprofen<sup style="top: -0.2081em;">® </sup>Voltaren<sup style="top: -0.2081em;">® </sup></p><p><em>This is not a complete list of brands with products that contain acetaminophen or an NSAID. </em></p><p>*NSAID stands for nonsteroidal anti-inflammatory drug. The third party trademarks used herein are trademarks of their respective owners. © Johnson & Johnson Consumer Inc. 2019 EST-567328 </p><p><em>Order patient education, samples, and coupons at </em></p><p>TylenolProfessional.com </p><p><strong>Not a member? </strong>Register today! </p><p>Acetaminophen and NSAIDs are found in hundreds of medicines </p><p>Your patients may not know. Remind them to always read and follow the label, and take only one medicine that contains the same kind of active ingredient at a time. This may help reduce the risk of harmful side effects. </p><p>Common medicines that contain <strong>acetaminophen </strong></p><p><strong>OTC </strong></p><p>Alka-Seltzer Plus<sup style="top: -0.2359em;">®* </sup></p><p>BENADRYL<sup style="top: -0.2359em;">® </sup></p><p>Comtrex<sup style="top: -0.2359em;">® </sup>Contac<sup style="top: -0.2359em;">® </sup>Coricidin<sup style="top: -0.2359em;">® </sup>Dimetapp<sup style="top: -0.2359em;">® </sup>Dristan<sup style="top: -0.2359em;">®* </sup>Excedrin<sup style="top: -0.2359em;">®* </sup>FeverAll<sup style="top: -0.2359em;">® </sup>Goody’s<sup style="top: -0.2359em;">®* </sup>Midol<sup style="top: -0.2359em;">®* </sup></p><p><strong>Prescription </strong></p><p></p><ul style="display: flex;"><li style="flex:1">Tylox<sup style="top: -0.2359em;">® </sup></li><li style="flex:1">Mucinex<sup style="top: -0.2359em;">® </sup></li></ul><p>NyQuil<sup style="top: -0.2359em;">® </sup>DayQuil<sup style="top: -0.2359em;">® </sup>Pamprin<sup style="top: -0.2359em;">® </sup>Robitussin<sup style="top: -0.2359em;">® </sup></p><p>SUDAFED<sup style="top: -0.2359em;">®† </sup></p><p>Tavist<sup style="top: -0.2359em;">® </sup>Theraflu<sup style="top: -0.2359em;">® </sup></p><p>TYLENOL<sup style="top: -0.2359em;">® </sup></p><p>Vanquish<sup style="top: -0.2359em;">® </sup>Vicks<sup style="top: -0.2359em;">® </sup><br>Endocet<sup style="top: -0.2359em;">® </sup>Fioricet<sup style="top: -0.2359em;">® </sup>Lorcet<sup style="top: -0.2359em;">® </sup><br>Ultracet<sup style="top: -0.2359em;">® </sup>Vicodin<sup style="top: -0.2359em;">® </sup><br>Lortab<sup style="top: -0.2359em;">® </sup>Maxidone<sup style="top: -0.2359em;">® </sup>Norco<sup style="top: -0.2359em;">® </sup>Percocet<sup style="top: -0.2359em;">® </sup>Roxicet<sup style="top: -0.2359em;">™ </sup>TYLENOL<sup style="top: -0.2359em;">® </sup>with Codeine </p><p>Common medicines that contain an <strong>NSAID </strong></p><p></p><ul style="display: flex;"><li style="flex:1"><strong>OTC </strong></li><li style="flex:1"><strong>Prescription </strong></li></ul><p></p><p></p><ul style="display: flex;"><li style="flex:1">Mobic<sup style="top: -0.2359em;">® </sup></li><li style="flex:1">Advil<sup style="top: -0.2359em;">® </sup></li></ul><p>Aleve<sup style="top: -0.2359em;">® </sup><br>Ecotrin<sup style="top: -0.2359em;">® </sup>Excedrin<sup style="top: -0.2359em;">®* </sup>Goody’s<sup style="top: -0.2359em;">®* </sup>Midol<sup style="top: -0.2359em;">®* </sup><br>Celebrex<sup style="top: -0.2359em;">® </sup>Clinoril<sup style="top: -0.2359em;">® </sup>Daypro<sup style="top: -0.2359em;">® </sup>Dolobid<sup style="top: -0.2359em;">® </sup>Feldene<sup style="top: -0.2359em;">® </sup>Ibuprofen Inocin<sup style="top: -0.2359em;">® </sup><br>Naproxen Relafen<sup style="top: -0.2359em;">® </sup>Toradol<sup style="top: -0.2359em;">® </sup>Ultracet<sup style="top: -0.2359em;">® </sup>Vicoprofen<sup style="top: -0.2359em;">® </sup>Voltaren<sup style="top: -0.2359em;">® </sup><br>Alka-Seltzer Plus<sup style="top: -0.2359em;">®* </sup>Anacin<sup style="top: -0.2359em;">® </sup>Bayer<sup style="top: -0.2359em;">® </sup></p><p>BC<sup style="top: -0.2359em;">®* </sup></p><p>Bufferin<sup style="top: -0.2359em;">® </sup>Dristan<sup style="top: -0.2359em;">®* </sup></p><p>MOTRIN<sup style="top: -0.2359em;">® </sup></p><p>Lodine<sup style="top: -0.2359em;">® </sup></p><p><em>This is not a complete list. </em></p><p>*Many OTC brands (like Midol<sup style="top: -0.1388em;">® </sup>and Alka-Seltzer Plus<sup style="top: -0.1388em;">®</sup>) have different formulations that contain acetaminophen or an NSAID. †Not all SUDAFED<sup style="top: -0.1388em;">® </sup>formulations contain acetaminophen. <strong>REFERENCES: 1. </strong>US Food and Drug Administration. FDA strengthens warning of heart attack and stroke risk for non-steroidal anti-inflammatory drugs. https://<a href="/goto?url=http://www.fda.gov/ForConsumers/ConsumerUpdates/ucm453610.htm" target="_blank">www.fda.gov/ForConsumers/ConsumerUpdates/ucm453610.htm. Accessed January 12, 2018. </a><strong>2. </strong>Catella-Lawson F, Reilly MP, Kapoor SC, et al. Cyclooxygenase inhibitors and the antiplatelet effects of aspirin. <em>N Engl J Med. </em>2001;345(25):1809-1817. <strong>3. </strong>Elliott WJ. Drug interactions and drugs that affect blood pressure. <em>J Clin Hypertens. </em>2006;8(10):731-737. <strong>4. </strong>Radack KL, Deck CC, Bloomfield SS. Ibuprofen interferes with the efficacy of antihypertensive drugs. <em>Ann Intern Med. </em>1987;107:628-635. The third party trademarks used herein are trademarks of their respective owners. © Johnson & Johnson Consumer Inc. 2019 EST-567328 </p>
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