CURRICULUM VITAE PERSONAL DATA Name: Bernard W. Agranoff EDUCATION Cass Technical High School, Detroit, Michigan, 1941-44 The University of Michigan, Ann Arbor, 1944-46 Wayne State Medical School, Detroit, Michigan, 1946-50, M.D. The University of Michigan, Ann Arbor, B.S. Chemistry, 1954 POSTDOCTORAL TRAINING Intern: Guthrie Clinic and Robert Packer Hospital, Sayre, Pennsylvania, 1950 Fellow: Massachusetts Institute of Technology, Department of Biology, 1951-52 SENIOR POSTDOCTORAL TRAINING NIH Special Leave: Max Planck Institut fur Zellchemie (F. Lynen), Munich, Germany, 1958-59 Sabbatical Leave: National Institute for Medical Research (R.M. Gaze), London, England, 1974-75 ACADEMIC APPOINTMENTS Biochemist, Section on Lipid Chemistry, National Institute of Neurological Diseases and Blindness, National Institutes of Health, Bethesda, Maryland, 1954-60 Research Scientist, Chief, Section of Biochemistry, Mental Health Research Institute, The University of Michigan, Ann Arbor, Michigan, 1960 Associate Professor, Department of Biological Chemistry, Medical School, The University of Michigan, Ann Arbor, Michigan, 1961-65 Professor, Department of Biological Chemistry, Medical School, The University of Michigan, Ann Arbor, Michigan, 1965- Professor, Department of Psychiatry, Medical School, The University of Michigan,Ann Arbor, Michigan, 1983- Ralph Waldo Gerard Professor of Neurosciences (Endowed Chair), 1991- Senior Research Scientist, The University of Michigan, 1997- Agranoff/ 2 ACADEMIC ADMINISTRATIVE APPOINTMENTS Coordinator of Biological Sciences, Mental Health Research Institute, The University of Michigan, Ann Arbor, Michigan, 1963-67 Associate Director, Mental Health Research Institute, The University of Michigan, Ann Arbor, Michigan, 1977-83 Acting Director, Mental Health Research Institute, The University of Michigan, Ann Arbor, Michigan, 1977, 1983-84 Acting Director, Neuroscience Laboratory Building, The University of Michigan, Ann Arbor, Michigan, 1983 Director, Neuroscience Laboratory Building, The University of Michigan, Ann Arbor, Michigan, 1984- Scientific Director, Mental Health Research Institute, The University of Michigan, Ann Arbor, Michigan, 1984-85 Director, Mental Health Research Institute, The University of Michigan, Ann Arbor, Michigan, 1985-95 CONSULTING POSITIONS Industrial Consultant, 1960- HEW, Office of Education, 1968-69 Multiple Sclerosis Society, 1973 National Advisory Eye Council, 1983 SCIENTIFIC ACTIVITIES Editorial Boards Advances in Lipid Research, Advisory Editor, 1962-67 Michigan Mental Health Research Bulletin, Editorial Consultant, 1968-72 Behavioral Biology, 1970-78 Journal of Biological Chemistry, 1971-76 Biological Psychiatry, 1972-78 Journal of Neurochemistry, 1972-82 Deputy Chief Editor, 1982-85 Biochemistry, Pharmacology and Behavior, Advisory Editor, 1973-88 Brain Research, 1974- Advances in Neurochemistry (Series Editor), 1975- Neurochemical Research, 1976-84 Molecular Neurobiology, 1987-97 Neuroscience Research Communications, 1987-1995 Advances in Neuroscience, 1989- Neurokhimia, (Honorary), 1990-1995; 1998- Neuropsychopharmacology, 1993-1995 NIH Extramural Committees NIH Fellowship Panel on Biochemistry and Nutrition, 1964-1967 Agranoff/ 3 Neurology “A” Study Section, NIH, 1967-71 Neurology “B” Study Section, NIH, 1975-79 Consultant, NIMH Board of Scientific Consultants, 1977 GRANT SUPPORT Current: NIH-MH 42652 “Regulation of Phosphoinositide-Linked CNS Receptors” Bernard W. Agranoff, M.D., Program Director 4 Co-Investigators Total Project Period: 07/01/93-06/30/98; No cost extension 7/1/98-6/30/99 Subproject 1: “Lithium and the Regulation of CNS Signal Transduction Bernard W. Agranoff, M.D. , Principal Investigator 20% Effort Total Project Period: No cost extension 7/1/98-6/30/99 Core Support Facilities 5% Effort Total Project Period: No cost extension 7/1/98-6/30/99 Frontiers in Neuroscience Gift of Ralph and Elsie Colton Total Project Period: 1993- CERTIFICATION AND LICENSURE Medical Licensure: State of Michigan, 1951 MILITARY SERVICE A.S. V-12 (U.S. Navy), The University of Michigan, 1944-45 LT (MC) U.S. Navy, Naval Medical School, Bethesda, Assistant Officer in Charge, t then Officer in Charge, Department of Chemistry, 1952-54 HONORS AND AWARDS Phi Eta Sigma 1944 Phi Kappa Phi (Distinguished Member, 1973) 1945 Agranoff/ 4 E.S. Lee Medical History Award 1946 Maimonides Society Fellowship 1946-48 Fellow of the National Foundation for Infantile Paralysis, 1951-52 Department of Biology, Massachusetts Institute of Technology (with F.O. Schmitt) Distinguished Service Citation, Wayne State Medical School 1967 Annual Grass Foundation Lecturer Society for Neuroscience, Baltimore, MD Chapter 1976 Society for Neuroscience, Shreveport, LA Chapter 1979 Society for Neuroscience, Greater Hartford, CT Chapter 1979 Society for Neuroscience, Indianapolis, IN Chapter 1983 Society for Neuroscience, Central Missouri Chapter 1987 Society for Neuroscience, Louisville KY Chapter 1993 Distinguished Neurochemistry Lecturer, UCLA 1981 Distinguished Faculty Achievement Award, University of Michigan 1984 Distinguished Faculty Lectureship in Biomedical Research, 1986 University of Michigan Distinguished Lecturer, Baylor College of Medicine, Program in 1986 Neuroscience, Henry Russel Lecturer, University of Michigan 1988 NIH Fogarty Scholar-in-Residence Award 1988 Institute of Medicine 1991 Michigan Scientist of the Year Award 1992 Boots Distinguished Neuroscience Lecturer, Louisiana State 1992 University, School of Medicine, Shreveport, LA Wayne State University Medical School Distinguished Alumnus 1993 Award “Festschrift” issue, Neurochemical Research 1994 Symposium in honor of Dr. Agranoff, American Society for 1996 Neurochemistry Symposium in honor of Dr. Agranoff, University of Michigan 1997 Faculty Outstanding Service Recognition Award, Neuroscience 1999 Executive Committee, Neuroscience Program, University of Michigan MEMBERSHIPS AND OFFICES IN PROFESSIONAL SOCIETIES American Chemical Society, 1954- American Society for Biochemistry and Molecular Biology, 1959- International Society for Neurochemistry, 1966- Council Member, 1973-77 Treasurer, 1985-1989 Chairman, 1989-1991 Association for Research in Nervous and Mental Diseases, 1968- American Society for Neurochemistry, 1969- Council Member, 1969-73, 1977-79 President, 1973-75 American College of Neuropsychopharmacology, 1969- Agranoff/ 5 Fellow, 1972- Society for Neuroscience, 1969- Council, 1977-80 American Psychological Association, 1972- Fellow, 1973 New York Academy of Sciences, Fellow, 1977 American Psychological Society, Fellow, 1990- Dana Alliance for Brain Initiatives, Member 1997- American Association for the Advancement of Science, Fellow 1998 International Union of Pharmacology, Section on Neuropsychopharmacology, Member, 1999 TEACHING ACTIVITIES Visiting Lecturer, Weizmann Institute, Rehovot, Israel, 1971 Co-editor, over 6 editions (25 years), of “Basic Neurochemistry”, a reference textbook. Highlights at U-M Originated and taught a biennial neurochemistry course, 1967-1987, and have since lectured in the course. Participated in graduate and medical student teaching; post-graduate lectures to psychiatry residents and fellows. Chaired or co-chaired Ph.D. dissertation committees in Biological Chemistry, Neuroscience, Toxicology, and Biopsychology. COMMITTEES AND ADMINISTRATIVE SERVICE National Organizing Committee, American Society for Neurochemistry, 1969-70 Advisory Committee on Fundamental Research, National Multiple Sclerosis Society, 1970-73 U.S. National Academy of Sciences Committee for the International Brain Research Organization , 1972-75 National Commission on Multiple Sclerosis Panel on Biochemistry, Chairman, 1973 International Society for Neurochemistry, Program Chairman, 7th Meeting, 1977-79 Society for Neuroscience, Chairman, Task Force on Finance, 1982 Program Committee, Gordon Conference on Plasticity, 1982-86 Society for Neuroscience, Publication Committee, 1983 American Society for Neurochemistry, Program Committee Chairman, 1985 External Review Board, The Burke Rehabilitation Center, Cornell University, 1986 American College of Neuropsychopharmacology, Education and Training Committee, 1989-91 External Review Committee, Mayo Clinic Cerebrovascular Research Center, 1990 External Advisory Committee, Beckman Institute for Advanced Science and Technology, University of Illinois at Champaign-Urbana, 1990-93 Agranoff/ 6 International Society for Cerebral Blood Flow and Metabolism, Publications Committee, 1991-95 American College of Neuropsychopharmacology, Program Committee, 1991-96 International Society for Neurochemistry, Standing Rules Committee, 1993- American Society for Neurochemistry, Electronic Networking Subcommittee, 1995- 98 American College of Neuropsychopharmacology, Credentials Committee, 1998- University Executive Committee, Mental Health Research Institute, 1969- Rackham Research Committee, 1971 Executive Committee, Neuroscience Program, 1971-88 Advisory Committee, Department of Biological Chemistry, 1973-75 Society of Fellows, Senior Fellow, 1973-78 Society of Fellows, Executive Committee, 1976-78 Neural and Behavioral Science Committee, Medical School, 1975-91 Mental Health Research Institute Review Committee, Chairman, 1976 Physiology Search Committee, Co-Chairman, 1977-78 Committee on Recognition, Department of Biological Chemistry, Chairman, 1977-79 PET Executive Committee, 1979- Executive Committee, Medical School, 1979-82 Medical School Deanship Committee, Co-Chairman, 1982-1983 Dean’s Committee