21 COUNTRY PROFILES An Introduction to Local Pharmaceutical Production Opportunities in Africa TABLE OF CONTENTS: Foreword from UNAIDS 01 02 Foreword from CCCMHPIE Acknowledgements 03 Introduction to Country Profiles 04 Country Profile 1: ALGERIA 11 Country Profile 2: ANGOLA 14 Country Profile 3: CÔTE D’IVOIRE 17 Country Profile 4: EGYPT 20 Country Profile 5: ETHIOPIA 23 Country Profile 6: GABON 26 Country Profile 7: GHANA 29 Country Profile 8: KENYA 32 Country Profile 9: MADAGASCAR 35 Country Profile 10: MALAWI 38 Country Profile 11: MALI 41 Country Profile 12: MAURITIOUS 44 Country Profile 13: MOZAMBIQUE 47 Country Profile 14: NIGERIA 50 Country Profile 15: RWANDA 53 Country Profile 16: SENEGAL 56 Country Profile 17: SOUTH AFRICA 59 Country Profile 18: TANZANIA 62 Country Profile 19: UGANDA 65 Country Profile 20: ZAMBIA 68 Country Profile 21: ZIMBABWE 71 Bibliography 74 FOREWORD FROM UNAIDS A healthy population is essential for prosperity. also strongly believe that local production of This is a now accepted principle of development, medicines and other health products in Africa reflected in the UN Sustainable Development is an attractive proposition - it is estimated Goals agreed in 2015, and in particular SDG3 that the African pharmaceutical sector holds for good health and wellbeing. The principle is a US $45 billion market opportunity by 2020. also reflected in the African continent’s vision Local pharmaceutical manufacturing in African for itself – Agenda 2063, also published in 2015 countries presents an opportunity to save lives by the African Union, and in collective actions while creating jobs and improving the local since 2015 by African countries to strengthen economy. their systems – for instance by their unanimous adoption of a treaty in May 2018 to set up However, our work with international partners an African Medicine Agency (AMA). Indeed, has revealed that there remains a huge lack health is a priority for most African country of information and misunderstanding about development plans for good reason. The African African countries, their needs, their status continent has approximately 15 percent of the and opportunities. This is particularly acute in global population and a disproportionately high China where language barriers and very recent disease burden. It is the continent where over 70 economic development hinders understanding percent of the world’s HIV cases and 90 percent of global markets. of deaths due to malaria occur. I appreciate that our partners here in China – At the same time, many African countries are the China Chamber of Commerce for Import highly dependent on imported pharmaceutical and Export of Medicines and Health Products and medical products. It is estimated that more (CCCMHPIE), and the whole of UNAIDS than 80 percent of Anti-Retroviral drugs (ARVs) has supported this effort to provide a simple, used on the continent are imported from outside, consistent set of information for Chinese and with 70 percent of all pharmaceutical and other companies considering local production medical products market being served by foreign in African countries. With this effort, we hope imports. Where there is local manufacturing, it they will all begin to realise the openness and mainly involves the production of non-complex, willingness of African governments to bring in high volume essential products, such as basic foreign investors into this sector, create joint analgesics, simple antibiotics, anti-malarial partnerships, and inspire as many companies drugs and vitamins. This is an unsustainable as possible to set a vision for how they can situation for two reasons. Imported products contribute to saving lives on the continent, in a can be subject to mark-ups, while jobs are sustainable yet profitable manner. urgently needed on the continent, which local manufacturing could provide for. This is why UNAIDS is so focused on encouraging global pharmaceutical manufacturers – including from China - to set up in African countries. This is based on the strong conviction (also articulated in the African Union Roadmap on Shared Responsibility and Global Solidarity, endorsed by Heads of States in 2012) that access to affordable, quality medication is integral to Ms Amakobe Sande ending AIDS (and other major diseases) and UNAIDS Country Director and achieving Universal Health Coverage. We Representative to the People’s Republic of China 1 FOREWORD FROM CCCMHPIE China accounts for 20% of the world’s population, international organizations and other stake and the healthcare sector is a crucial contributor holders to set the bridge between China and to China’s development. China has strong supply Africa and let more Chinese companies learn side capacity, which attracts foreign companies more about African markets to support their as the second largest market of the world. There business strategy in the long term. are an estimated more than 5,000 domestic pharmaceutical manufacturers. And the market In 2016, CCCMHPIE, the Joint United Nations is continuing to grow and strengthen, to provide Programme on HIV/AIDS (UNAIDS) China universal health insurance and give individuals office and the Bill & Melinda Gates Foundation greater access to products and services. At jointly launched the China-Africa Medical and the same time, we are keen to collaborate Health Cooperation Platform Project (www. internationally to establish and promote healthcac.com), establishing an online database international standards as well as support other to share information about capacity of Chinese countries to address their health challenges. So companies and the market demand of African far, 45 APIs, 24 preparations, 4 vaccines, 3 IVDs countries, organizing regular events and and 2 vector control products have passed the releasing various reports. We hope that this new World Health Organization Pre-Qualification to market profile of 21 African countries, especially enter global pharmaceutical markets. Hundreds the Chinese version, can help Chinese companies of products have been registered successfully in (as well as others from other countries) to go into USFDA, European and the emerging counties and invest in local African manufacturing. authorities. We appreciate UNAIDS’s support for China- As an emerging market for China, the Africa Africa cooperation. We will use these profiles continent is key to our efforts. Health has in our efforts to promote collaboration, and been a long-standing key part of China- Africa look forward to working with UNAIDS and cooperation, initially in the 1960s through other international organizations to continue to medical aid and more recently through support further access to medicines in Africa. exports of relevant drugs to African countries. In December 2015, President Xi Jinping announced the China-Africa Ten Collaboration Plan at the Johannesburg Summit of Forum on China-Africa Cooperation, and for the first time explicitly encouraged the local production of pharmaceuticals in Africa to promote access to medicines, through factory building and other direct investment. In September 2018, the Eight Major Initiatives of the FOCAC Beijing meeting emphasis more on actions follow up in health cooperation. Supported by China’s Ministry of Commerce, CCCMHPIE has focused its efforts and facilitated Chinese companies’ performance in Africa. So far, enterprises such as Humanwell Healthcare, Guilin Pharmaceutical, Shanghai Pharmaceuticals, Sansheng, Yorkool, Tasly and other enterprises have built factories or branches Zhou Hui in Mali, Ethiopia, Uganda and elsewhere. President, China Chamber of Commerce CCCMHPIE is ready to work with the relevant for Import and Export of Chinese Medicines and Health Products 2 ACKNOWLEDGEMENTS UNAIDS China Office and CCCMPHIE would Gabon: Export Promotion Agency Gabon like to take this opportunity to acknowledge all parties who contributed to the development and Ghana: Senior Member of the Pharmaceuticals finalization of these 21 Country Profiles. Manufacturers Association We would like to acknowledge and thank Madagascar: Senior Official from the Ministry of a number African Embassies to China, Public Health who collaborated with us to verify the data presented in the Country Profiles, in particular Mauritius: Private sector representative and the Embassies of Angola, Egypt, Ethiopia, Senior Official pharmaceutical sector, Ministry Madagascar, Malawi, Rwanda, Senegal, South of Health Africa, Tanzania, Uganda and Zambia. Malawi: Chinese manufacturer At country level, we wish to sincerely Nigeria: Representative, private pharmaceutical acknowledge the support and input of the manufacturer UNAIDS Offices in Algeria, Cote D’Ivoire, Kenya, Madagascar, Mali, Mauritius, Zambia: Zambian Medicine Regulatory Mozambique, Nigeria and Zimbabwe who Authority and Zambia Development Agency worked with respective governments to also validate the contents of the report. The COMESA Secretariat Regional Teams in Johannesburg, Dakar and Cairo and well as colleagues in UNAIDS Last but not least, we would like to extend our Headquarters also provided valuable technical sincere thanks to Development Reimagined, an input. independent consulting firm based in China, for the huge undertaking of putting together, We are also indebted and grateful to the completing, designing and translating this following decision-makers, experts and report and supporting the partnership between resource persons who also contributed to the UNAIDS China office and CCCMPHIE is content and verification of data in