J. Qian: Supplementary Table 2 1 Supplementary Table 2. Up-regulated genes in H6c7eR-Kr cells with signal log ratio >=2 Signal Unigene Log Ratio Gene Symbol Title Hs.104636 2 TULP2 tubby like protein 2 Hs.108080 2 CSRP1 cysteine and glycine-rich protein 1 solute carrier family 1 (glutamate/neutral amino Hs.323878 2 SLC1A4 acid transporter), member 4 Hs.172816 2 NRG1 neuregulin 1 Hs.376206 2 KLF4 Kruppel-like factor 4 (gut) serine (or cysteine) proteinase inhibitor, clade G Hs.384598 2 SERPING1 (C1 inhibitor), member 1, (angioedema, hereditary) Hs.123159 2 SPAG4 sperm associated antigen 4 Hs.132380 2 FAXDC1 fatty acid hydroxylase domain containing 1 Hs.9003 2 FLJ13868 hypothetical protein FLJ13868 Hs.80409 2 GADD45A growth arrest and DNA-damage-inducible, alpha Hs.284217 2 SDCCAG33 serologically defined colon cancer antigen 33 Hs.337774 2 ARHGEF2 rho/rac guanine nucleotide exchange factor (GEF) 2 Hs.51133 2 PTK6 PTK6 protein tyrosine kinase 6 Homo sapiens transcribed sequence with strong similarity to protein sp:P07478 (H.sapiens) TRY2_HUMAN Trypsin II precursor (Anionic Hs.447753 2 --- trypsinogen) v-maf musculoaponeurotic fibrosarcoma oncogene Hs.460889 2 MAFF homolog F (avian) Hs.47313 2 KIAA0258 KIAA0258 gene product Hs.31210 2 BCL3 B-cell CLL/lymphoma 3 Hs.94392 2.1 LOC51157 LDL induced EC protein Hs.146233 2.1 NEURL neuralized-like (Drosophila) Hs.376792 2.1 CDH4 cadherin 4, type 1, R-cadherin (retinal) Hs.296638 2.1 PLAB prostate differentiation factor Hs.370771 2.1 CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) Hs.348802 2.1 NMA putative transmembrane protein Hs.100194 2.1 ALOX5AP arachidonate 5-lipoxygenase-activating protein Hs.301664 2.1 RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 Hs.438862 2.1 EPS8L1 EPS8-like 1 Hs.83169 2.2 MMP1 matrix metalloproteinase 1 (interstitial collagenase) cytochrome P450, family 1, subfamily B, Hs.154654 2.2 CYP1B1 polypeptide 1 Hs.86947 2.2 ADAM8 a disintegrin and metalloproteinase domain 8 matrix metalloproteinase 3 (stromelysin 1, Hs.375129 2.2 MMP3 progelatinase) J. Qian: Supplementary Table 2 2 Hs.2030 2.2 THBD thrombomodulin Hs.512648 2.2 C6orf59 chromosome 6 open reading frame 59 Homo sapiens transcribed sequence with strong similarity to protein ref:NP_073729.1 (H.sapiens) microtubule-associated proteins 1A/1B light chain Hs.506947 2.2 --- 3 [Homo sapiens] Hs.73793 2.2 VEGF vascular endothelial growth factor Hs.435699 2.2 PRSS3 protease, serine, 3 (mesotrypsin) Hs.437647 2.2 FLJ10415 hypothetical protein FLJ10415 prostaglandin-endoperoxide synthase 2 Hs.196384 2.3 PTGS2 (prostaglandin G/H synthase and cyclooxygenase) Homo sapiens cDNA clone IMAGE:3880075, Hs.400876 2.3 --- partial cds Hs.81008 2.3 FLNB filamin B, beta (actin binding protein 278) Hs.103915 2.3 KIAA0346 KIAA0346 protein solute carrier family 1 (glutamate/neutral amino Hs.323878 2.3 SLC1A4 acid transporter), member 4 Hs.212892 2.3 PRLR prolactin receptor Hs.46679 2.3 C14orf34 chromosome 14 open reading frame 34 Hs.250632 2.3 FLJ11078 hypothetical protein FLJ11078 diphtheria toxin receptor (heparin-binding Hs.799 2.3 DTR epidermal growth factor-like growth factor) Hs.127826 2.3 EPOR erythropoietin receptor Hs.356061 2.3 MAP1LC3B microtubule-associated protein 1 light chain 3 beta Hs.65135 2.3 KIAA0913 KIAA0913 protein serine (or cysteine) proteinase inhibitor, clade B Hs.75716 2.3 SERPINB2 (ovalbumin), member 2 Hs.276916 2.3 NR1D1 nuclear receptor subfamily 1, group D, member 1 Hs.217754 2.3 FLJ22202 hypothetical protein FLJ22202 Hs.79432 2.4 FBN2 fibrillin 2 (congenital contractural arachnodactyly) Hs.73853 2.4 BMP2 bone morphogenetic protein 2 potassium voltage-gated channel, subfamily G, Hs.118695 2.4 KCNG1 member 1 Hs.155651 2.4 FOXA2 forkhead box A2 Hs.172851 2.4 ARG2 arginase, type II Hs.135183 2.4 CENTA1 centaurin, alpha 1 Hs.41502 2.4 C14orf139 chromosome 14 open reading frame 139 Hs.77768 2.4 DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 Hs.103527 2.4 SH2D2A SH2 domain protein 2A diphtheria toxin receptor (heparin-binding Hs.799 2.5 DTR epidermal growth factor-like growth factor) Hs.6846 2.5 LPPR2 lipid phosphate phosphatase-related protein type 2 J. Qian: Supplementary Table 2 3 Hs.126256 2.5 IL1B interleukin 1, beta Hs.246381 2.5 CD68 CD68 antigen Hs.73793 2.5 VEGF vascular endothelial growth factor chromobox homolog 4 (Pc class homolog, Hs.5637 2.5 CBX4 Drosophila) Hs.110571 2.5 GADD45B growth arrest and DNA-damage-inducible, beta wingless-type MMTV integration site family, Hs.512714 2.5 WNT7B member 7B Hs.126256 2.5 IL1B interleukin 1, beta Hs.232770 2.5 ALOXE3 arachidonate lipoxygenase 3 dolichyl-p-mannose:Man7GlcNAc2-PP-dolichyl Hs.77575 2.5 ALG12 mannosyltransferase Hs.128071 2.6 FLJ21302 hypothetical protein FLJ21302 Hs.446644 2.6 PSG1 pregnancy specific beta-1-glycoprotein 1 fucosyltransferase 3 (galactoside 3(4)-L- Hs.169238 2.7 FUT3 fucosyltransferase, Lewis blood group included) Hs.436943 2.7 SOCS3 suppressor of cytokine signaling 3 Hs.13011 2.7 GTPBP2 GTP binding protein 2 Hs.171003 2.8 CBS cystathionine-beta-synthase Hs.155109 2.9 HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 Hs.282209 3 PON1 paraoxonase 1 Hs.73853 3 BMP2 bone morphogenetic protein 2 Hs.73793 3.1 VEGF vascular endothelial growth factor Hs.110571 3.2 GADD45B growth arrest and DNA-damage-inducible, beta Hs.106070 3.2 CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) Hs.171695 3.3 DUSP1 dual specificity phosphatase 1 Hs.321164 3.3 NPAS2 neuronal PAS domain protein 2 Hs.411311 3.4 IL24 interleukin 24 Hs.318567 3.5 NDRG1 N-myc downstream regulated gene 1 Hs.2258 3.5 MMP10 matrix metalloproteinase 10 (stromelysin 2) Hs.2050 3.5 PTX3 pentaxin-related gene, rapidly induced by IL-1 beta Hs.105434 3.6 ISG20 interferon stimulated gene 20kDa Hs.7972 3.7 RIPX rap2 interacting protein x solute carrier family 7 (cationic amino acid Hs.14846 3.7 SLC7A1 transporter, y+ system), member 1 Hs.417050 4 CCNA1 cyclin A1 nuclear factor of kappa light polypeptide gene Hs.73090 4.1 NFKB2 enhancer in B-cells 2 (p49/p100) Hs.336046 4.1 IL13RA2 interleukin 13 receptor, alpha 2 Hs.155651 4.2 FOXA2 forkhead box A2 Hs.419 4.4 DLX2 distal-less homeo box 2 J. Qian: Supplementary Table 2 4 Hs.66 4.4 IL1RL1 interleukin 1 receptor-like 1 death effector filament-forming Ced-4-like Hs.511937 4.6 DEFCAP apoptosis protein Hs.171695 4.9 DUSP1 dual specificity phosphatase 1 .