Melanie S. Sanford Department of Chemistry University of Michigan Ann Arbor, MI 48109 Tel. (734) 615-0451 Fax (734) 647-4865 [email protected] Research Group: http://www.umich.edu/~mssgroup/ EDUCATION: Ph.D., Chemistry June 2001 California Institute of Technology, Pasadena, CA Thesis Title: Synthetic and Mechanistic Investigations of Ruthenium Olefin Metathesis Catalysts B.S.; M.S. cum laude with Distinction in Chemistry June 1996 Yale University, New Haven, CT CURRENT POSITION: University of Michigan, Ann Arbor, MI Moses Gomberg Distinguished University Professor of Chemistry September 2016 – present Arthur F. Thurnau Professor of Chemistry July 2011 – present PREVIOUS POSITIONS: University of Michigan, Ann Arbor, MI Moses Gomberg Collegiate Professor of Chemistry January 2012 – Sept 2016 Professor of Chemistry September 2010 – June 2011 Associate Professor of Chemistry May 2007 – August 2010 William R. Roush Assistant Professor of Chemistry October 2006 – May 2007 Assistant Professor of Chemistry July 2003 – October 2006 Princeton University, Princeton, NJ NIH NRSA Postdoctoral Fellow August 2001 – June 2003 Advisor: Professor John T. Groves California Institute of Technology, Pasadena, CA Graduate Student August 1997 – July 2001 Advisor: Professor Robert H. Grubbs Yale University, New Haven, CT Undergraduate Student September 1994 – June 1996 Advisor: Professor Robert H. Crabtree Naval Research Laboratory, Washington, DC Summer Intern Summer 2003, 2004, 2005 Advisor: Dr. David W. Conrad AWARDS: Honorary Doctorate, University of South Florida (2018); Blavatnik Award (2017); ACS Fellow (2016); Distinguished University Professor (2016); Elected Member, National Academy of Sciences (2016); Elected Fellow, American Academy of Arts and Sciences (2016); SABIC Young Catalysis Investigator Award (2015); OMCOS Award (2015); UM Faculty Recognition Award (2014); ACS Sierra Nevada Section: Distinguished Chemist Award (2013); Raymond and Beverly Sackler Prize in Chemistry (2013); Tetrahedron Young Investigator Award in Synthetic Chemistry (2013); ACS Ipatieff Prize (2013); Thieme-IUPAC Prize (2012); Moses Gomberg Collegiate Chair (2012); Paul N. Rylander Award (2012); Classical High School Distinguished Alumni Award (2012); MacArthur Foundation Fellowship (2011); Royal Society of Chemistry Fluorine Prize (2011); Fellow of American Association for Advancement of Science (2011); ACS Award in Pure Chemistry (2011); Arthur F. Thurnau Professorship (2011); National Fresenius Award (2010); Melanie S. Sanford p. 2 AWARDS (CONT): John Dewey Award for Undergraduate Education (2010); LSA Excellence in Teaching Award (2010); BASF Catalysis Award (2009); ACS Arthur C. Cope Scholar Award (2008); Dupont Young Investigator Award (2007); Roche Excellence in Chemistry Award (2007); GlaxoSmithKline Chemistry Scholars Award (2006); Abbott Young Investigator Award (2006); Presidential Early Career Award for Scientists and Engineers (2006); AstraZeneca Excellence in Chemistry Award (2006); Research Corporation Cottrell Scholar Award (2006); Alfred P. Sloan Research Fellow (2006); National Science Foundation CAREER Award (2006); Bristol Myers Squibb “Freedom to Discover” Award (2006); Eli Lilly Grantee Award (2005); Amgen Young Investigator Award (2005); Boehringer Ingelheim New Investigator Award in Organic Synthesis (2005); Beckman Young Investigator Award (2004); Camille and Henry Dreyfus Foundation New Faculty Award (2003); NIH NRSA Postdoctoral Fellowship (2001); Herbert Newby McCoy Award for Graduate Research (2001); Arthur Fleischer Award for Undergraduate Research (1996); East Coast Athletic Conference Scholar-Athlete Award (1996); National Science Scholar (1993); NCAA Gymnastics Academic All-American (1993-1996) EDITORIAL and EDITORIAL ADVISORY BOARDS: Journal of the American Chemical Society (Associate Editor) 2014-present Accounts of Chemical Research (Advisory Board) 2014-present Asian Journal of Organic Chemistry (Advisory Board) 2012-present Advanced Synthesis and Catalysis (Advisory Board) 2011-present ACS Catalysis (Advisory Board) 2011-present Synthesis and Synlett (Advisory Board) 2009-present Tetrahedron/Tetrahedron Letters (Advisory Board) 2015-present RESEARCH PUBLICATIONS [*] represents independent publication; undergraduate co-authors are underlined *(179) Roy, P.; Bour, J. R.; Sanford, M. S. “Synthesis and Reactivity of Ni(II) and Ni(III) Aminoquinoline 3 Complexes for C(sp )–H Amination to form β-Lactams,” 2019, manuscript in preparation. *(178) Roberts, C. R.; Camasso, N. M.; Bowes, E. G.; Sanford, M. S. “Reactivity and Selectivity Towards C–C versus C–O Bond Formation at High Valent Nickel Alkyl Complexes,” 2019, manuscript submitted. *(177) Meucci, E. A.; Sanford, M. S. “Aryl–Fluoride Bond-Forming Reactions at Nickel(IV) Centers,” 2019, manuscript submitted. *(176) Lee, S. J.; Brooks, A. F.; Ichiishi, N.; Makaravage, K. J.; Mossine, A. V.; Sanford, M. S.; Scott, P. J. H. “C– H [18F]Fluorination of 8-Methylquinolines with Ag18F,” Chem. Commun. 2019, asap article. *(175) Ferguson, D. M.; Malapit, C. M.; Bour, J. R.; Sanford, M. S. “Palladium-Catalyzed Difluoromethylation of Aryl Chlorides and Bromides with TMSCF2H,” J. Org. Chem. 2019, in press. *(174) Lee, M.; Adams, A.; Cox, P. B.; Sanford, M. S. “Access to 3D Alicyclic Amine-Containing Fragments through Transannular C–H Arylation,” Synlett 2019, asap article. *(173) Melvin, P. R.; Ferguson, D. M.; Schimler, S. D.; Bland, D. C.; Sanford, M. S. “Room Temperature Deoxyfluorination of Benzaldehydes and α-Ketoesters with Sulfuryl Fluoride and Tetramethylammonium Fluoride,” Org. Lett. 2019, asap article. *(172) Lee, S. J.; Makaravage, K. J.; Brooks, A. F.; Sanford, M. S.; Scott, P. J. H. “Cu-Mediated Aminoquinoline- Directed Radiofluorination of Aromatic C–H Bonds with KF,” Angew. Chem. Int. Ed. 2019, asap article. *(171) Ferguson, D. M.; Bour, J. R.; Canty, A. J.; Kampf, J. W.; Sanford, M. S. “Aryl–CF3 Coupling from Phosphinoferrocene-Ligated Palladium(II) Complexes,” Organometallics 2019, asap article. Melanie S. Sanford p. 3 *(170) Aguilera, E. Y.; Sanford, M. S. “Model Complexes for the Palladium-Catalyzed Transannular C–H Functionalization of Alicyclic Amines,” Organometallics 2019, 38, 138-142. *(169) Yang, L.; Brooks, A.; Makaravage, K.; Zhang, H.; Sanford, M. S.; Scott, P.; Shao, X. “Radiosynthesis of [11C]LY2795050 for Preclinical and Clinical PET Imaging Using Cu(II)-mediated Cyanation,” ACS Med. Chem. Lett. 2018, 9, 1274-1279. *(168) Schimler, S. D.; Froese, R. D. J.; Bland, D. C.; Sanford, M. S. “Reactions of Arylsulfonate Electrophiles with NMe4F: Mechanistic Insight, Reactivity, and Scope,” J. Org. Chem. 2018, 83, 11178-11190. R *(167) Mantell, M. A.; Kampf, J. W.; Sanford, M. S. “Improved Synthesis of [Cp RhCl2]2 Complexes,” Organometallics 2018, 37, 3240-3242. *(166) Malapit, C. A.; Bour, J. R.; Brigham, C. E.; Sanford, M. S. “Base-Free Nickel-Catalysed Suzuki-Miyaura Couplings of Carboxylic Acid Fluorides,” Nature 2018, 563, 100-104. *(165) Cabrera, P. J.; Lee, M.; Sanford, M. S. “Second Generation Palladium Catalyst System for Transannular C–H Functionalization of Azabicycloalkanes,” J. Am. Chem. Soc. 2018, 140, 5599-5606. *(164) Makaravage, K. J.; Shao, X.; Brooks, A. F.; Sanford, M. S.; Scott, P. J. H. “Copper(II) Mediated [11C]Cyanation of Arylboronic Acids and Aryl Stannanes,” Org. Lett. 2018, 20, 1530-1533. *(163) James, B. R.; Boissonnault, J. A.; Wong-Foy, A. G.; Matzger, A. J.; Sanford, M. S. “Structure Activity Relationships in Metal-Organic Framework Catalysts for the Synthesis of Propylene Carbonate from CO2 and Propylene Oxide,” RSC Adv. 2018, 8, 2132-2137. *(162) Shrestha, A.; Lee, M.; Dunn, A. L.; Sanford, M. S. “Palladium-Catalyzed C–H Bond Acetoxylation via Electrochemical Oxidation,” Org. Lett. 2018, 20, 204-207. *(161) Hendriks, K. H.; Robinson, S. G.; Braten, M. N.; Sevov, C. S.; Helms, B. A.; Sigman, M. S.; Minteer, S. D.; Sanford, M. S. “High Performance Oligomeric Catholytes for Effective Macromolecular Separation in Nonaqueous Redox Flow Batteries,” ACS Cent. Sci. 2018, 4, 189-196. *(160) Mossine, A.; Brooks, A.; Bernard-Gauthier, V.; Bailey, J.; Ichiishi, N.; Schirmacher, R.; Sanford, M. S.; Scott, P. J. H. “Synthesis of PET Radiotracers by Copper-Mediated 18F Radiofluoronation of Organoborons: Importance of Order of Addition and Copeting Protodeborylation,”J. Lab. Comp. Radiopharm. 2018, 61, 228-236. *(159) Ichiishi, N.; Malapit, C. A.; Wozniak, L.; Sanford, M. S. “Palladium and Nickel-Catalyzed Decarbonylative C–S Coupling to Convert Thioesters to Thioethers,” Org. Lett. 2018, 20, 44-47. *(158) Camasso, N. M.; Canty, A. J.; Ariafard, A.; Sanford, M. S. “Experimental and Computational Studies of High Valent Nickel and Palladium Complexes,” Organometallics, 2017, 36, 4382-4393. *(157) Sevov, C. S.; Hendriks, K. H.; Sanford, M. S. “A Low Potential Pyridinium Anolyte for Aqueous Redox Flow Batteries,” J. Phys. Chem. C 2017, 121, 24376-24380. *(156) Malapit, C. A.; Ichiishi, N.; Sanford, M. S. “Pd-Catalyzed Decarbonylative Cross-Couplings of Aroyl Chlorides,” Org. Lett. 2017, 19, 4142-4145. *(155) Hendriks, K. H.; Sevov, C. S.; Cook, M. E.; Sanford, M. S. “Multi-Electron Cycling of a Low Potential Anolyte in Inexpensive Alkalai Metal Electrolytes for Non-Aqueous Redox Flow Batteries,” ACS Energy Lett. 2017, 2, 2430-2435. *(154) McCammant, M. S.; Thompson, S.; Krska, S. W.; Scott, P. J. H.; Sanford, M. S. “Copper-Mediated C(sp2)–H Nucleophilic Radiofluorination of Electron Rich (Hetero)Arenes,” Org. Lett. 2017, 19, 3939-3942. *(153) Ferguson,