Chemical and Biochemical Engineering 1 Chemical and Facilities Biochemical Undergraduate Core Materials Science Laboratory Engineering The Materials Science Laboratory is equipped with optical microscopes and facilities for metallographic preparation. Chair Mechanical tensile testing instruments, heat treatment and • C. Allan Guymon sintering furnaces, and hardness testing machines also are available. Teaching aids include metallography specimen kits Undergraduate major: chemical engineering (B.S.E.) and crystallography packages. Graduate degrees: M.S. in chemical and biochemical engineering; Ph.D. in chemical and biochemical engineering Required Undergraduate Faculty: https://cbe.engineering.uiowa.edu/people Website: https://cbe.engineering.uiowa.edu/ Laboratories Chemical and biochemical engineers combine engineering Chemical Engineering Laboratory principles with knowledge of mathematics and specific The Chemical Engineering Laboratory provides instruction sciences—chemistry, the biological sciences, and physics— for undergraduate students in CBE:3150 Thermodynamics/ to develop and operate processes that convert raw materials Transport Laboratory and CBE:3155 Chemical Reaction into products that benefit society. For example, biochemical Engineering/Separations Laboratory. It is equipped for engineers might develop and operate processes to convert experimentation in thermodynamics, fluid flow, heat switchgrass into biofuels or to mass produce an antibiotic. transfer, mass transfer, chemical reaction engineering, and Chemical and biochemical engineers engage in a wide variety separations. The lab includes pilot plant equipment, such of activities that benefit the global community. Fuel cells, as a distillation column, wiped film evaporator, shell-and- solar energy, and biorenewable fuels (e.g., biodiesel or tube heat exchanger, jacketed kettle, and agitated extractor. ethanol) fall within the realm of chemical engineering. Other equipment includes a concentric tube heat exchanger, reciprocating plate extractor, membrane gas separator, Chemical engineering distinguishes itself from other fluid friction apparatus, and heat conduction apparatus. engineering professions with its reliance on chemical Analytical equipment includes gas chromatographs, UV-visible reactions and physicochemical transformations to produce a spectrophotometers, polarimeters, and refractometers. wide variety of important materials and products. Biochemical engineers are involved in a wide variety of industrial The lab is continuously updated to reflect advances at the biocatalytic, fermentation, and cell culture processes that forefront of chemical engineering technology. Additionally, generate products ranging from the high fructose corn syrup a wide array of small equipment is available to support in soft drinks to recombinant human insulin. laboratory projects and demonstrations in chemical engineering courses and for use by students performing As part of their training, chemical and biochemical engineers independent investigations. learn ethical design and a respect for the larger issues in any design, such as community health, employee safety, Chemical Process Safety Laboratory and the global implications of the design. The University of Iowa's curriculum emphasizes chemical process safety and The Chemical Process Safety Laboratory is an integral part environmentally conscious chemical engineering design. of CBE:3125 Chemical Process Safety. It is equipped with two MiniFlash automatic flash point testers (closed cap), an advanced reactive system screening tool (ARSST), a Programs minimum ignition energy (MIE) apparatus, a flammability chamber, a modified Hartmann tube, a Hartmann bomb, Undergraduate Program of Study a liquid conductivity apparatus, a powder changeability apparatus, a powder volume resistivity apparatus, a Van Major de Graaff generator, two high impedance electrometers, a • Major in Chemical Engineering (Bachelor of Science in field meter, a Faraday cage, and relief sizing software. This Engineering) equipment is used in a series of experiments to demonstrate the principles of flammability, reactivity, explosions, relief Graduate Programs of Study valve sizing, and electrostatics relevant to industry. Majors Biochemical Engineering Laboratory • Master of Science in Chemical and Biochemical The Biochemical Engineering Laboratory is an integral part Engineering of CBE:3205 Introduction to Biochemical Engineering. It is equipped with two controlled New Brunswick BioFlo/CelliGen • Doctor of Philosophy in Chemical and Biochemical 115 bioreactors, three New Brunswick C76 Water Bath Engineering Shakers, a UV-visible spectrometer, a Thermo Scientific NanoDrop 3300 fluorospectrometer, and a YSI 2700 Select Biochemistry Analyzer. This equipment is used to study the growth and metabolism of microorganisms and recombinant protein production. 2 Chemical and Biochemical Engineering Process Control Laboratory Laboratory and field equipment includes aerosol samplers, including scanning mobility particle sizers for aerosols from The Process Control Laboratory is a modern, computer-based 3 nanometer to 1 micron with time resolution to 30 seconds; instructional laboratory that is integral to CBE:4105 Process aerosol particle sizers for aerodynamic measurements of in Dynamics and Control in Design. The lab consists of computer situ particles with time resolution to 1 second; and varied control of a shell-and-tube heat exchanger and a level-and- condensation particle counters for measuring total particle flow control process rig with state-of-the art industrial control counts. Several hygroscopic tandem differential mobility interfaces. analyzers are used, as well as varied aerosol generation The Computer Control Laboratory offers an ensemble of devices and unique aerosol inlets for relative humidity (RH) learning experiences with the same equipment. Additional and temperature modification and control. Cloud droplet laboratories provide instruction in the use of process number can be measured in the lab or in the field using simulators that provide analogies and better insight into a Droplet Measurement Technologies cloud condensation the control process. Topics include determination of the nuclei detector. Advanced computer control of instruments is gain and time constants for single-capacitance systems; available through LabVIEW. determination of gain, time constant, and damping factor Selected instruments are field deployable in a custom air- of second-order processes; determination of open-loop and conditioned trailer. Through collaboration with the IIHR— closed-loop response to step-and-ramp changes in input Hydroscience & Engineering, access to micrometeorology for single-capacitance and multicapacitance processes; sensors, 1D and 2D elastic and Raman lidar, and gas sensors approximations of multicapacitance systems as first- is available, including multichannel ammonia monitors. and second-order processes with dead time; analysis of instrumentation characteristics and transfer functions; tuning Biochemical Engineering and optimization of feedback control parameters (P, PI, PID); Biochemical engineering laboratories provide facilities for system identification through frequency response methods; preparation of biological media and cultivation of organisms and determination of system stability. as well as for separation and analysis of biomolecules. This Experimental arrangements in the lab are simple enough in equipment includes biological incubators and floor incubator design to be easily understood, yet complicated enough to shakers, agitated and airlift bioreactors, light microscopes, help students appreciate system characteristics inherent in autoclaves, Vi-Cell cell counter, thermocycler for polymerase industrial processes (e.g., large time lags, error in parameter chain reaction (PCR) amplification of DNA, high- and low- estimation). speed centrifuges, UV-Vis spectrophotometers, a lyophilizer, biological safety cabinets, and an anaerobic glove box. Phase- Graduate Facilities and contrast and epifluorescence microscopes, gel electrophoresis systems, gas chromatography units with flame ionization and Laboratories electron capture detectors, and several high performance The department offers a wide variety of facilities to support liquid chromatography systems with refractive index and and develop research activities. photodiode array detectors are available for characterization of microorganisms and constituent biomolecules. Air Pollution Computational, Field, and Through collaborative research agreements, graduate Laboratory Studies students also have access to specialized facilities for electron The department maintains extensive facilities for microscopy, large-scale fermentation, protein structure, computational, field, and laboratory studies of air pollution, recombinant DNA research, and tissue culture/hybridoma; carbon cycle gases, aerosols, and nanoparticles at the Center the Flow Cytometry Facility; and the High Resolution Mass for Global and Regional Environmental Research (CGRER). Spectrometry Facility. The center occupies 5,000 square feet of lab and office space on the fourth floor of the Iowa Advanced Technology Biomedical Engineering Laboratories. The biomedical engineering laboratories house particle technology equipment including microemulsion equipment CGRER houses one R2 ImmersaDesk Portable Large Scale for drug encapsulation, sonicators, benchtop scale spray Visualization System and is linked on campus to two more R2