CURRICULUM VITAE Karen E. Burke, M.D., Ph.D. River Court, 429 East 52 Street, New York, NY 10022 Tel: (212) 754-1100 Fax: (212) 754-1943 email: [email protected] EDUCATION: B.A. (1967) Cornell University, Ithaca, N.Y.: Chemistry Major, Physics and French Minor M.A. (1969) Cornell University, Ithaca, N.Y.: Biophysics and Chemistry (Dr. Harold Scheraga) 1972 N.I.H. Predoctoral Fellowship, Department of Biophysical Research, The Weizmann Institute of Science, Rehovot, Israel (Dr. Harold Scheraga) Ph.D. (1973) Cornell University, Ithaca, N.Y.: Biophysics (Dr. Harold Scheraga) 1972-1973 N.I.H. Postdoctoral Fellowship, Department of Biochemistry, Cornell University Medical College, New York, N.Y. (Dr. Alton Meister) 1973-1974 N.I.H. Postdoctoral Fellow, Department of Cellular Immunology, The Rockefeller University, New York, N.Y. (Dr. Samuel C. Silverstein) M.D. (1978) New York University Medical College, New York, N.Y. 1978-1979 Internship in Internal Medicine, Montefiore Hospital, Bronx, N.Y. 1979-1980 N.I.H. Training Grant, Department of Dermatology, New York University Medical Center, New York, N.Y. (Dr. Irma Gigli) 1980-1983 Resident, Dermatology, New York University Medical Center, New York, N.Y. ACADEMIC APPOINTMENTS: 1986-1989 Clinical Investigator and Research Associate, Department of Orthopedics, Mount Sinai Medical Center, New York, N.Y. 1989-1990 Visiting Investigator, Memorial Sloan-Kettering Cancer Foundation, New York, N.Y. 1991-1996 Clinical Member, Scripps Clinic and Research Foundation, La Jolla, Ca. 2004-Present Department of Dermatology, Mount Sinai Medical Center, New York, N.Y. 2004-8 Clinical Investigator; 2008-15 Assistant Clinical Investigator; 2015-Present Associate Clinical Professor HOSPITAL APPOINTMENTS: 1983-2008 Attending Physician, Assistant Clinical Professor, Department of Medicine, Cabrini Medical Center, New York, N.Y. 2004-Present Department of Dermatology, Icahn School of Medicine at Mount Sinai Medical Center, New York, N.Y., Associate Clinical Professor since 2015 CERTIFICATION: 1979 National Board of Medical Examiners 1985 National Board of Dermatology LICENSURE: 1979 New York Medical License 139006 1984 California Medical License G-52287 1985 North Carolina Medical License 29081 DEA Registration AB2161468 APPOINTMENTS/EMPLOYMENT: 1985-1993 Clinical Research Director, Wilson Dermatology Clinic, Wilson, N.C. 1986-1989 Clinical Investigator and Research Associate, Department of Orthopedics, Mount Sinai Medical Center, New York, N.Y. 1987-1997 Clinical Research Director, Greensboro Specialty Surgical Center, Greensboro, N.C. CV FDA (4/12/17) 1 KAREN E. BURKE, M.D., Ph.D. 1989-1990 Visiting Investigator, Department of Dermatology, Memorial Sloan-Kettering Cancer Foundation, New York, N.Y. 1991-1996 Clinical Member, Scripps Clinic and Research Foundation, La Jolla, Ca. 1998-2001 Scientific Research Consultant, Helena Rubinstein, L’Oréal, Paris, France 2012-2015 Scientific Research Consultant, Klox Technologies, Laval, Quebec, Canada 2016-Present Scientific Research Consultant, THEVAX Genetics Vaccine USA, Inc., Cape Canaveral, FL HONORS/AWARDS: 1963-1967 Cornell University Dean’s List 1967 Cornell University Magna Cum Laude with Honors in Chemistry and with Distinction in all Subjects 1969 Citation for Excellent Research from Sigma Delta Epsilon, Women in Science 1983 Resident’s Research Publications, Journal of Dermatology and Oncology, Second Prize 1983 American Academy of Dermatology, Exchange Fellowship Award 1992 Singular Sensations Achievement Award 2001, 2003 New York Magazine The Best Doctors in New York 2001-2017 Castle Connolly Top Doctors New York Metro Area 2009 Honorary Life Governor, New York Academy of Sciences 2009 Police Athletic League (PAL) Women of the Year Award, New York 2010 Distinguished Women Award, Northwood University 2014 Elected to American Dermatological Association 2014 Presidential Citation from the American Academy of Dermatology 2016 Elected to the Board of the American Dermatological Association 2016 Award from UNDWC (United Nations Delegates Welcoming Committee) for the Balsam Project (which provides health and educational support to Syrian refugee women and children living in six villages on the Syrian/Turkish border) PATENTS: US Patent Number: 4,865,840 TOPICAL COMPOSITION CONTAINING SELENOAMINO ACIDS FOR THE PREVENTION OF ULTRAVIOLET RADIATION-INDUCED SKIN DAMAGE Date of Patent: April 29, 1987 US Patent Number: 5,330,757 METHOD FOR THE PREVENTION AND REVERSAL OF THE EXTRINSIC AGING OF THE SKIN BY TRANSDERMAL APPLICATION OF SELENOAMINO ACIDS AND COMPOSITIONS THEREFORE Date of Patent: July 19, 1994 This patent is also in Canada, Europe (Austria, Denmark, France, Germany, Great Britain, Ireland, Belgium, Italy, Luxemburg, Monaco, Netherland, Portugal, Sweden), Asia (Australia, Japan, Korea, Singapore) OTHER PROFESSIONAL ROLES: Memberships in Professional Organizations with Leadership or Active Role: 1998- Member, Board of Directors, Parkinson’s Disease Foundation 2004- Member, Antoinette Circle, The Skin Cancer Foundation 2005- Member, Nominating Committee, Women’s Dermatologic Society 2007- Member, General and Plastic Surgery Devices Panel Advisory Committee, FDA 2009- Honorary Life Governor, New York Academy of Sciences 2009- Member, Board of Directors, New York Stem Cell Foundation CV FDA (4/12/17) 2 KAREN E. BURKE, M.D., Ph.D. 2014- Scientific Advisory Council, MDSolarSciences 2014- Member, Melanoma Research Alliance Dermatology Council 2016- Scientific Research Consultant, THEVAX Genetics Vaccine USA, Inc. 2016- Member, Board of Directors, American Dermatological Association 1987-1994 Member, Board of Directors, United Nations Affiliated World Transfer, Inc 1999-2003 Member, Committee of International Affairs, American Academy of Dermatology 2000-2006 Member, President’s Council, New York Academy of Sciences 2005-2008 Member, Board of Directors, Women’s Dermatologic Society 1999-2009 Member, Board of Governors of the New York Academy of Sciences 2012-2015 Scientific Research Consultant, Klox Technologies, Laval, Quebec, Canada Memberships in Professional Organizations: (*Uncertain of exact dates) 1983- Member, American Academy of Dermatology 1986- Member, Women’s Dermatologic Society 1987- Member, American Society of Dermatologic Surgery 1988-* Member, American Medical Association 1994- Member, The Dermatology Foundation 2013- Member, New York County Medical Society 2014- Member, American Dermatological Association 2016- Member, Bellevue Alumni Society 1983-2014* Member, Society of Investigative Dermatology 1992-2014 Member, American Association for the Advancement of Science 2007-2014* Member, International Society of Dermatology Elected membership in honor societies: 2009-present Honorary Life Governor, New York Academy of Sciences 2014-present Elected to American Dermatological Association 2016-present Member, Board of Directors, American Dermatological Association Appointed memberships to editorial boards: 1998- Member, Editorial Board, Cutis 2007- Member, Editorial Board, Aesthetic Dermatology News 2007- Member, Editorial Board, Cosmetics in Dermatology 2007- Associate Editor, Journal of Drugs in Dermatology 1989-2000 Medical and Science Editor, Diplomatic World Bulletin, United Nations, New York, N.Y. and author of “Health Update” column and other articles Extramural service: 1994- President, The Karen E. Burke Research Foundation, Inc. 1994- Founder and President, Longévité, Ltd. 1995- Member, United Nations Women’s International Forum 2005- Volunteer Service to Police Athletic League (PAL) 2008- Member, Advisory Board, One Bright World (builds schools in Africa) 2008- Member, Advisory Council, Fisher Pei LLC (Lifestyle Design Services) 2010- Member, President’s Council of Cornell Women, Cornell University 2016- Member, Board of Directors, United Nations Delegates Welcome Committee 2016- Member, UN Women for Peace 2017- Trustee Emeritus, Poly Prep Country Day School 1995-2014* Member, Committee of Human Rights, New York Academy of Sciences CV FDA (4/12/17) 3 KAREN E. BURKE, M.D., Ph.D. 2002-2016 Trustee, Poly Prep Country Day School 2011-2012 Served in medical brigade: Nestros Pequeños Hermanos, Honduras 2015- Sponsor of the Vienna ACUNS (Academic Council on the United Nations System) which focuses on issues related to human rights (especially prevention of violence toward women (including femicide) and equal opportunities for women and youth) 2015- Sponsor of the Balsam Project (which provides health and educational support to Syrian refugee women and children living in six villages on the Syrian/Turkish border) PUBLICATIONS: Peer Reviewed Original Contributions 1. Burke Platzer, Karen E. and Scheraga, Harold A. “The NH2-terminal Amino Acid of Bovine Prothrombin,” Biophys. Acta. 207, 262-267, 1970. 2. Burke Platzer, Karen E., Momany, Frank A. and Scheraga, Harold A. “Conformational Energy Calculations of Enzyme-Substrate Interactions. I. Computation of Preferred Conformations of Some Substrates with Chymotrypsin.” Internat. J. Peptide Protein Research 4, 187-193, 1972. 3. Burke Platzer, Karen E., Momany, Frank A. and Scheraga, Harold A. “Conformational Energy Calculations of Enzyme-Substrate Interactions. II. Computation of the Binding Energy for Substrates in the Active Site of Chymotrypsin.” Internat. J. Peptide Protein Research 4, 201-209, 1972. 4. Burke Platzer, Karen E., Momany, Grank A. and Scheraga, Harold A. “Conformational Energy Calculations of Enzyme-Substrate Interactions. III. Computation of the Binding Energy for Substrates