10th Glasgow Paediatric Research Day Friday 8h November 2019 Teaching and Learning Centre, Queen Elizabeth University Hospital Campus 0900 – 0920 Registration 0920 – 0930 Welcome: Dr Chris Halsey 0930 – 1020 Session 1 Long oral communications Chair Dr Helen McDevitt 0930 – 0940 Childhood constipation is inherited and not caused by low fibre David Tappin, School of Medicine, Dentistry & Nursing, University of Glasgow 0940 – 0950 A quick PEWS (qPEWS) : a viable alternative to the PEWS in the pre-hospital and resource limited settings Kevin Rooney, School of Health & Life Sciences, University of the West of Scotland 0950 – 1000 Gestational diabetes and altered placental vascular function : a potential mechanism for adverse pregnancy outcome Sharon Mackin, Institute of Cardiovascular & Medical Sciences, University of Glasgow 1000 – 1010 Real world estimates of adrenal insufficiency related adverse events in congenital adrenal hyperplasia Salma Rashid Ali, School of Medicine, Dentistry & Nursing, University of Glasgow 1010 – 1020 What is the relationship between placement stability and disturbances of attachment in infants in foster care Orla MacPherson, Institute of Health & Wellbeing, University of Glasgow 1020 – 1050 Coffee Break 1050 – 1250 Invited Speakers Session: Implementing Rare Disease Plans Chair Professor Faisal Ahmed 1050 – 1130 Professor Agnes Linglart, Bicêtre Hospital, Paris-Sud University, Paris "Supporting expert centres for rare diseases - A Challenge’” 1130 – 1210 Professor Tim Barrett, Centre for Rare Disease, Birmingham Children’s Hospital, UK “Bringing research into the clinic – The Birmingham Rare Disease Network” 1210 – 1250 Dr Martina Rodie, Office for Rare Conditions, Glasgow “The Office for Rare Conditions – Progress so far” 1250 – 1300 Presentation of Yorkhill prizes – Professor Faisal Ahmed 1300 – 1400 Lunch & poster presentations @UofGChildHealth #GPRD19 10th Glasgow Paediatric Research Day Friday 8h November 2019 Teaching and Learning Centre, Queen Elizabeth University Hospital Campus 1400 – 1500 Session 2 Long oral communications Chair Dr James Paton 1400 – 1410 Establishing risk of STEC-HUS into adulthood; paediatric long-term outcome (up to 40 years) in Scotland; 1967-2018 Victoria Harkins, Royal Hospital for Children, NHS Greater Glasgow & Clyde 1410 – 1420 Can heterozygous PKHD1 variants cause polycystic kidney disease Rebecca Jackson, Royal Free Hospital, London 1420 – 1430 The role of the bone marrow microenvironment in childhood AML Alison Laing, Institute of Cancer Sciences, University of Glasgow 1430 – 1440 Vascular dysfunction in boys with hypospadias Angela Lucas-Herald, Institute of Cardiovascular & Medical Sciences, University of Glasgow 1440 – 1450 Evaluation of CCL17 (TARC) as a diagnostic biomarker for classic Hodgkin lymphoma: interim results from the CANDEL study Annette Lake, Institute of Infection, Immunity and Inflammation, University of Glasgow 1450 – 1520 Coffee Break 15.25 – 16.10 Session 3 Short oral communications Chair Dr Martina Rodie 1520 – 1525 Age and gender-specific reference data for high resolution magnetic resonance based musculoskeletal parameters In healthy children and young people Huda El Sharkasi, School of Medicine, Dentistry & Nursing, University of Glasgow 1525 – 1530 Should children presenting with a first episode of status epilepticus have genetic testing? Joseph Symonds, Royal Hospital for Children, NHS Greater Glasgow & Clyde 1530 – 1535 Ultrasound and microbubble gene delivery for targeting altered placental microRNAs Sonya Frazier, Institute of Cardiovascular & Medical Sciences, University of Glasgow 1535 – 1540 Longitudinal changes in external masculinisation scores in boys with XY disorder of sex development Malika Alimussina, School of Medicine, Dentistry & Nursing, University of Glasgow 1540 – 1545 Deprivation, time to presentation and risk of perforation in paediatric acute appendicitis : Ross Bogle, Royal Hospital for Children, NHS Greater Glasgow & Clyde @UofGChildHealth #GPRD19 10th Glasgow Paediatric Research Day Friday 8h November 2019 Teaching and Learning Centre, Queen Elizabeth University Hospital Campus 15.45 – 16.10 Continuation of Session 3 Short oral communications Co-Chaired Dr Angela Lucas-Herald & Dr Alison Laing 1545 – 1550 Reversion to baseline microbiome during food-reintroduction, after successful course of exclusive enteral nutrition (EEN) in paediatric Crohn’s disease (CD), parallels with exacerbation of gut inflammation Michael Logan, School of Medicine, Dentistry & Nursing, University of Glasgow 1550 – 1555 Interactions among influenza and other respiratory viruses: implications for the impact of the childhood influenza immunisation programme in Scotland Sema Nickbakhsh, Institute of Infection, Immunity and Inflammation, University of Glasgow 1555 – 1600 Comorbidity and mortality in SCN1A positive Dravet syndrome – a 10-year follow-up study Benjamin Dunwoody, Royal Hospital for Children, NHS Greater Glasgow & Clyde 1600 – 1605 Association and independent effect of individual Childsmile interventions with child oral health Jamie Brian Rutherford Kidd, School of Medicine, Dentistry & Nursing, University of Glasgow 1605 – 1610 Pre-hospital PEWS is not a useful predictor of the need for hospital admission from ED Kate Booth, School of Health & Life Sciences, University of the West of Scotland 16:10 - 16:15 Online Feedback of GPRD 2019 16.15 - 16.20 GPRD prize winners & close of meeting – Dr Chris Halsey @UofGChildHealth #GPRD19 .