Anti-MOCOS (aa 243-359) polyclonal antibody (DPABH-02998) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Antigen Description Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. In vitro, the C-terminal domain is able to reduce N-hydroxylated prodrugs, such as benzamidoxime. Immunogen Recombinant fragment, corresponding to amino acids 243-359 of Human MOCOS. Isotype IgG Source/Host Rabbit Species Reactivity Human Purification Immunogen affinity purified Conjugate Unconjugated Applications WB, IHC-P Format Liquid Size 100 μl Buffer pH: 7.20; Constituents: 59% PBS, 40% Glycerol Preservative 0.02% Sodium Azide Storage Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. GENE INFORMATION Gene Name MOCOS molybdenum cofactor sulfurase [ Homo sapiens ] Official Symbol MOCOS Synonyms MOCOS; molybdenum cofactor sulfurase; MCS; MOS; HMCS; moCo sulfurase; molybdenum cofactor sulfurtransferase; 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Entrez Gene ID 55034 Protein Refseq NP_060417.2 UniProt ID Q96EN8 Pathway Defective AMN causes hereditary megaloblastic anemia 1; Defective CD32 causes methylmalonic aciduria; Defective GIF causes intrinsic factor deficiency; Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF. Function Mo-molybdopterin cofactor sulfurase activity; Mo-molybdopterin cofactor sulfurase activity; lyase activity; molybdenum ion binding 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved.