Ministry of Health Essential Medicines List for Uganda EMLU 2007 Essential Medicines List for Uganda 2007 © 2007 Ministry of Health All parts of this publication may be reproduced in any form, provided due acknowledgement is given Copies may be obtained from: The Principal Pharmacist Ministry of Health PO Box 7272, Kampala Uganda Ministry of Health Building Room C 105 Plot 6 Lourdel Road Wandegeya, Kampala Tel: 077-2512975 Email: [email protected] or [email protected] Printed and Bound by: Table of Contents Foreword............................................................................viii Preface................................................................................ xi Acknowledgements ............................................................xiii Essential Medicines Review committee ............................ xiv Contributing Clinical Specialists ......................................... xv Presentation of Information............................................... xvi Abbreviations and Units ...................................................xviii Summary of Main Changes in EDLU 2007 ..........................1 1. ANAESTHETICS .............................................................4 1.1 General anaesthetics and oxygen....................4 1.2 Local anaesthetics ...........................................4 1.3 Preoperative and peri-operative medication.....5 2. ANALGESICS, ANTIPYRETICS......................................5 2.1 Non-opioids......................................................5 2.2 Medicines used for gout...................................5 2.3 Opioid analgesics.............................................5 3. ANTI-ALLERGICS & MEDICINES USED IN ANAPHYLAXIS ...........................................................6 4. ANTIDOTES ....................................................................6 4.1 General ............................................................6 4.2 Specific ............................................................6 5. ANTIEPILEPTICS AND ANTICONVULSANTS................7 6. ANTI-INFECTIVE MEDICINES........................................7 6.1 Anthelmintics....................................................7 6.1.1 Intestinal anthelminthics................................7 6.1.2 Antifilarials.....................................................7 6.1.3 Antischistosomals .........................................8 6.2 Antibacterials ...................................................8 6.2.1 Beta Lactam Medicines.................................8 6.2.2 Other antibacterial medicines........................8 EMLU 2007 iii 6.2.3 Antileprosy medicines ...................................9 6.2.4 Antituberculosis medicines............................9 6.3 Antifungal medicines........................................9 6.4 Antiprotozoal medicines.................................10 6.4.1 Antiamoebic medicines ...............................10 6.4.2 Antileishmaniasis medicines .......................10 6.4.3 Antimalarial medicines ................................10 6.4.4 Antitrypanosomal medicines (African trypanosomiasis).......................................10 6.4.5 Antitrichomoniasis medicines......................10 6.4.6 Medicines used in toxoplasmosis................10 6.5 Antiviral medicines .........................................11 7. ANTIMIGRAINE MEDICINES ........................................11 7.1 Treatment of Acute Attacks............................11 7.2 Prophylaxis ....................................................11 8. ANTINEOPLASTIC & IMMUNOSUPPRESSIVE MEDICINES ..............................................................11 8.1 Immunosuppressive medicines......................11 8.2 Cytotoxic medicines .......................................11 8.3 Hormones and antihormones.........................12 9. ANTI-PARKINSONISM MEDICINES .............................12 10. MEDICINES AFFECTING THE BLOOD ......................12 10.1 Antianaemia medicines ................................12 10.2 Anticoagulants and antagonists ...................12 10.3 Fibrinolytic Medicines...................................13 11. BLOOD PRODUCTS & PLASMA SUBSTITUTES.......13 11.1 Plasma expanders .......................................13 11.2 Plasma extracts ...........................................13 12. CARDIOVASCULAR MEDICINES...............................13 12.1 Antianginal medicines ..................................13 12.2 Antidysrhythmic medicines...........................13 12.3 Antihypertensive medicines .........................13 iv EMLU 2007 12.4 Medicines used in heart failure ....................14 12.4.1 Cardiac glycosides ....................................14 12.4.2 Medicines used in vascular shock.............14 13. DERMATOLOGICAL MEDICINES...............................14 13.1 Topical antifungals .......................................14 13.2 Topical antiinfectives....................................14 13.3 Topical antiinflammatories and antipruritics .15 13.4 Keratoplastics and keratolytics.....................15 13.5 Scabicide .....................................................15 13.6 Pediculicide..................................................15 13.7 Other topical preparations............................15 14. DIAGNOSTIC MEDICINES..........................................15 14.1 Ophthalmic diagnostic medicines1 ...............15 14.2 Radiocontrast media ....................................16 15. DISINFECTANTS and ANTISEPTICS .........................16 15.1 Antiseptics....................................................16 15.2 Disinfectants ................................................16 16. DIURETICS..................................................................16 17. GASTROINTESTINAL MEDICINES ............................17 17.1 Antacids and other antiulcer medicines........17 17.2 Antiemetics ..................................................17 17.3 Antihaemorrhoidals ......................................17 17.4 Antispasmodics............................................17 17.5 Laxatives......................................................17 17.6 Medicines used in diarrhoea ........................17 17.6.1 For oral rehydration...................................17 17.6.2 Antidiarrhoeals1.........................................18 18. HORMONES, OTHER ENDOCRINE MEDICINES & CONTRACEPTIVES .................................................18 18.1 Adrenal hormones & synthetic substitutes ...18 18.2 Androgens....................................................18 18.3 Hormonal contraceptives .............................18 v EMLU 2007 18.4 Oestrogens ..................................................19 18.5 Insulins and other antidiabetic medicines.....19 18.6 Ovulation inducers .......................................19 18.7 Progestogens...............................................19 18.8 Thyroid hormones and antithyroid medicines19 19. IMMUNOLOGICALS2...................................................19 19.1 Immunological diagnostic medicines............19 19.2 Sera and immunoglobulins...........................19 19.3 Vaccines ......................................................20 19.3.1 Vaccines for routine immunisation ............20 19.3.2 Vaccines for specific groups of individuals 20 20. MUSCLE RELAXANTS & CHOLINESTERASE INHIBITORS .............................................................20 21. OPHTHALMOLOGICAL PREPARATIONS..................21 21.1 Antiinfective medicines.................................21 21.1.1 Antiinfective + antiinflammatory Medicines1 .................................................................21 21.2 Antiinflammatory medicines1 ........................21 21.3 Local anaesthetics1 ......................................22 21.4 Miotics and antiglaucoma medicines1 ..........22 21.5 Mydriatics.....................................................22 21.6 Astringents1..................................................22 22. OXYTOCICS & ANTI-OXYTOCICS .............................22 22.1 Oxytocics .....................................................22 22.2 Antioxytocics ................................................22 23. PERITONEAL & HAEMODIALYSIS SOLUTIONS .......22 24. PSYCHOTHERAPEUTIC MEDICINES........................23 25. MEDICINES ACTING ON THE RESPIRATORY TRACT ..................................................................................23 25.1 Antiasthmatic medicines ..............................23 25.2 Antitussive Medicines...................................24 25.3 Cough soothing preparation.........................24 vi EMLU 2007 26. SOLUTIONS CORRECTING WATER, ELECTROLYTE, & ACID-BASE DISTURBANCES ..............................24 26.1 For oral rehydration......................................24 26.2 Parenterals...................................................24 26.3 Miscellaneous ..............................................24 27. VITAMINS & MINERALS .............................................24 28. EAR, NOSE & OROPHARYNGEAL PREPARATIONS25 28.1 Ear preparations ..........................................25 28.2 Nasal preparations.......................................25 28.3 Oropharygeal preparations ..........................25 29. MEDICINES FOR NEUROSURGICAL USE ................26 29.1 For cerebral metabolism/perfusion...............26 30 ANTIRETROVIRAL MEDICINES ..............................26 30.1 Nucleoside reverse transcriptase inhibitors (NRTI) ..26 30.2 Protease Inhibitors (PI) ............................................26 30.3 Non – Nucleoside Reverse Transcriptase