Common Name: THALLIUM ACETATE CAS Number: 563-68-8 RTK Substance number: 3062 DOT Number: UN 1707 Date: December 2000 --------------------------------------------------------------------------- --------------------------------------------------------------------------- HAZARD SUMMARY * Thallium Acetate can affect you when breathed in and by * If you think you are experiencing any work-related health passing through your skin. problems, see a doctor trained to recognize occupational * Contact can irritate the skin and eyes. Repeated eye diseases. Take this Fact Sheet with you. contact can cause damage with loss of vision. * High exposure to Thallium Acetate can cause headache, WORKPLACE EXPOSURE LIMITS fatigue, weakness, mood changes, confusion, convulsions, The following exposure limits are for soluble Thallium coma and death. compounds (measured as Thallium): * Exposure to Thallium Acetate can cause poor appetite, nausea, vomiting, diarrhea, loss of hair, sleeplessness and OSHA: The legal airborne permissible exposure limit weight loss. (PEL) is 0.1 mg/m3 averaged over an 8-hour * Thallium Acetate may damage the nervous system workshift. causing numbness, "pins and needles," and/or weakness in the hands and feet. NIOSH: The recommended airborne exposure limit is * Thallium Acetate may affect the liver and kidneys. 0.1 mg/m3 averaged over a 10-hour workshift. IDENTIFICATION ACGIH: The recommended airborne exposure limit is Thallium Acetate is a silk white, sand-like powder. It is used 0.1 mg/m3 averaged over an 8-hour workshift. to separate ore constituents by flotation and as a medication. * The above exposure limits are for air levels only. When REASON FOR CITATION skin contact also occurs, you may be overexposed, even * Thallium Acetate is on the Hazardous Substance List though air levels are less than the limits listed above. because it is regulated by OSHA and cited by ACGIH, DOT, NIOSH, DEP, HHAG and EPA. WAYS OF REDUCING EXPOSURE * Definitions are provided on page 5. * Where possible, enclose operations and use local exhaust ventilation at the site of chemical release. If local exhaust HOW TO DETERMINE IF YOU ARE BEING ventilation or enclosure is not used, respirators should be EXPOSED worn. The New Jersey Right to Know Act requires most employers * Wear protective work clothing. to label chemicals in the workplace and requires public * Wash thoroughly immediately after exposure to Thallium employers to provide their employees with information and Acetate and at the end of the workshift. training concerning chemical hazards and controls. The * Post hazard and warning information in the work area. In federal OSHA Hazard Communication Standard, 1910.1200, addition, as part of an ongoing education and training requires private employers to provide similar training and effort, communicate all information on the health and information to their employees. safety hazards of Thallium Acetate to potentially exposed workers. * Exposure to hazardous substances should be routinely evaluated. This may include collecting personal and area air samples. You can obtain copies of sampling results from your employer. You have a legal right to this information under OSHA 1910.1020. THALLIUM ACETATE page 2 of 6 This Fact Sheet is a summary source of information of all Any evaluation should include a careful history of past and potential and most severe health hazards that may result from present symptoms with an exam. Medical tests that look for exposure. Duration of exposure, concentration of the damage already done are not a substitute for controlling substance and other factors will affect your susceptibility to exposure. any of the potential effects described below. --------------------------------------------------------------------------- Request copies of your medical testing. You have a legal right to this information under OSHA 1910.1020. HEALTH HAZARD INFORMATION Mixed Exposures Acute Health Effects * Because more than light alcohol consumption can cause The following acute (short-term) health effects may occur liver damage, drinking alcohol may increase the liver immediately or shortly after exposure to Thallium Acetate: damage caused by Thallium Acetate. * Contact can irritate the skin and eyes. WORKPLACE CONTROLS AND PRACTICES * High exposure to Thallium Acetate can cause headache, fatigue, weakness, mood changes, confusion, convulsions, Unless a less toxic chemical can be substituted for a hazardous coma and death. substance, ENGINEERING CONTROLS are the most effective way of reducing exposure. The best protection is to Chronic Health Effects enclose operations and/or provide local exhaust ventilation at The following chronic (long-term) health effects can occur at the site of chemical release. Isolating operations can also some time after exposure to Thallium Acetate and can last reduce exposure. Using respirators or protective equipment is for months or years: less effective than the controls mentioned above, but is sometimes necessary. Cancer Hazard * According to the information presently available to the In evaluating the controls present in your workplace, consider: New Jersey Department of Health and Senior Services, (1) how hazardous the substance is, (2) how much of the Thallium Acetate has not been tested for its ability to substance is released into the workplace and (3) whether cause cancer in animals. harmful skin or eye contact could occur. Special controls should be in place for highly toxic chemicals or when Reproductive Hazard significant skin, eye, or breathing exposures are possible. * According to the information presently available to the New Jersey Department of Health and Senior Services, In addition, the following control is recommended: Thallium Acetate has not been tested for its ability to affect reproduction. * Where possible, automatically transfer Thallium Acetate from drums or other storage containers to process Other Long-Term Effects containers. * Repeated eye contact can cause damage with loss of vision. Good WORK PRACTICES can help to reduce hazardous * Exposure to Thallium Acetate can cause poor appetite, exposures. The following work practices are recommended: nausea, vomiting, diarrhea, loss of hair, sleeplessness and weight loss. * Workers whose clothing has been contaminated by * Thallium Acetate may damage the nervous system Thallium Acetate should change into clean clothing causing numbness, "pins and needles," and/or weakness in promptly. the hands and feet. * Do not take contaminated work clothes home. Family * Thallium Acetate may affect the liver and kidneys. members could be exposed. * Contaminated work clothes should be laundered by MEDICAL individuals who have been informed of the hazards of exposure to Thallium Acetate. Medical Testing * Eye wash fountains should be provided in the immediate For those with frequent or potentially high exposure (half the work area for emergency use. TLV or greater), the following are recommended before * If there is the possibility of skin exposure, emergency beginning work and at regular times after that: shower facilities should be provided. * On skin contact with Thallium Acetate, immediately * Liver and kidney function tests. wash or shower to remove the chemical. At the end of the workshift, wash any areas of the body that may have If symptoms develop or overexposure is suspected, the contacted Thallium Acetate, whether or not known skin following are recommended: contact has occurred. * Vision testing * Exam of the nervous system. THALLIUM ACETATE page 3 of 6 * Do not eat, smoke, or drink where Thallium Acetate is * If while wearing a filter or cartridge respirator you can handled, processed, or stored, since the chemical can be smell, taste, or otherwise detect Thallium Acetate, or if swallowed. Wash hands carefully before eating, drinking, while wearing particulate filters abnormal resistance to smoking, or using the toilet. breathing is experienced, or eye irritation occurs while * Use a vacuum or a wet method to reduce dust during wearing a full facepiece respirator, leave the area clean-up. DO NOT DRY SWEEP. immediately. Check to make sure the respirator-to-face seal is still good. If it is, replace the filter or cartridge. If PERSONAL PROTECTIVE EQUIPMENT the seal is no longer good, you may need a new respirator. * Be sure to consider all potential exposures in your WORKPLACE CONTROLS ARE BETTER THAN workplace. You may need a combination of filters, PERSONAL PROTECTIVE EQUIPMENT. However, for prefilters or cartridges to protect against different forms of some jobs (such as outside work, confined space entry, jobs a chemical (such as vapor and mist) or against a mixture of done only once in a while, or jobs done while workplace chemicals. controls are being installed), personal protective equipment * Where the potential for high exposure exists, use a may be appropriate. MSHA/NIOSH approved supplied-air respirator with a full facepiece operated in a pressure-demand or other positive- OSHA 1910.132 requires employers to determine the pressure mode. For increased protection use in appropriate personal protective equipment for each hazard and combination with an auxiliary self-contained breathing to train employees on how and when to use protective apparatus operated in a pressure-demand or other positive- equipment. pressure mode. * Exposure to 15 mg/m3 (as Thallium) is immediately The following recommendations are only guidelines and may dangerous to life and health. If the possibility of exposure not apply to every situation.