OriGene Technologies, Inc. 9620 Medical Center Drive, Ste 200 Rockville, MD 20850, US Phone: +1-888-267-4436 [email protected] EU: [email protected] CN: [email protected] Product datasheet for TA327110 RFC1 Rabbit Polyclonal Antibody Product data: Product Type: Primary Antibodies Applications: IF, IHC, WB Recommended Dilution: WB 1:500 - 1:2000, IHC 1:50- 1:200, IF 1:50- 1:200 Reactivity: Human, Mouse, Rat Host: Rabbit Isotype: IgG Clonality: Polyclonal Immunogen: Recombinant protein of human RFC1 Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3 Concentration: lot specific Purification: Affinity purification Conjugation: Unconjugated Storage: Store at -20°C as received. Stability: Stable for 12 months from date of receipt. Gene Name: replication factor C subunit 1 Database Link: NP_002904 Entrez Gene 19687 MouseEntrez Gene 89809 RatEntrez Gene 5981 Human P35251 Background: This gene encodes the large subunit of replication factor C, a five subunit DNA polymerase accessory protein, which is a DNA-dependent ATPase required for eukaryotic DNA replication and repair. The large subunit acts as an activator of DNA polymerases, binds to the 3 end of primers, and promotes coordinated synthesis of both strands. It may also have a role in telomere stability. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Mar 2011] Synonyms: A1; MHCBFB; PO-GA; RECC1; RFC; RFC140 Protein Families: Transcription Factors This product is to be used for laboratory only. Not for diagnostic or therapeutic use. View online » ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 1 / 3 RFC1 Rabbit Polyclonal Antibody – TA327110 Protein Pathways: DNA replication, Mismatch repair, Nucleotide excision repair Product images: Western blot analysis of extracts of MCF-7 cell lines, using RFC1 antibody. Immunohistochemistry of paraffin-embedded human lung cancer using RFC1 antibody at dilution of 1:200 (400x lens). This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 2 / 3 RFC1 Rabbit Polyclonal Antibody – TA327110 Immunohistochemistry of paraffin-embedded rat lung using RFC1 antibody at dilution of 1:200 (400x lens). Immunofluorescence analysis of MCF7 cell using RFC1 antibody. Blue: DAPI for nuclear staining. This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 3 / 3.