Immunoassay Workflow Solutions Antibody Arrays, Luminex® Assays, ELISAs and Simple Plex™ Assays Table of Contents 4 Immunoassay Workflow Solutions 6 Immunoassay Offering by Molecule 27 Proteome Profiler® Antibody Arrays 34 Luminex® High Performance Assays 37 Luminex® Preconfigured Panels Human XL Cytokine Discovery Luminex ® High Performance Assay ✔ Broad selection choose any combination from all 45 analytes ✔ Superior accuracy tested side-by-side with other leading suppliers ✔ Flexible x Effects order any combination of analytes tri within the panel a y Sele M od ct tib io n n ✔ Easy to order A select analytes directly from r Formula the product datasheet ffe tio u n B tion a QC Tes d tin li g a alibr V C a t o r s rity y ea in a L s s A Learn more | rndsystems.com/human-xl From Screening to Validation, We Have Your Total Workflow Solution screening validation Inexpensive, Easy-to-use Screening Tool Untreated Proteome Profiler™ Antibody Arrays • Analyze up to 119 proteins simultaneously • Quickly assess complex signaling responses Treated Instrumentation: Only standard Western blotting equipment Learn more | rndsystems.com/proteomeprofiler Quantitative Multiplexing Luminex® Assays • The most accurate and flexible offering on the market • Measure up to 50 analytes simultaneously FLEXMAP 3D® Instrumentation: MAGPIX®, Luminex® 200™, FlexMAP 3D® Luminex® High Performance Assays • Rigorously validated for accuracy, precision, and reproducibility MAGPIX® • XL Discovery Cytokine Panel now available Luminex® 100/200™ Learn more | rndsystems.com/luminex Uncoated ELISAs DuoSet® ELISA Development Systems • Economical and adaptable to multiple platforms • Over 1,000 available covering 8 species Instrumentation: Dependent on the platform being utilized Learn more | rndsystems.com/elisa 4 screening validation Gold Standard Coated ELISA Kits Quantikine® ELISA Kits • Exhaustively validated for superior performance and reproducibility • The most referenced ELISAs in the literature Instrumentation: Any 96-well plate reader Learn more | rndsystems.com/elisa Automated, Highly Reproducible ELISA Platform Simple Plex™ Assays • Unprecedented reproducibility • Wide dynamic range and sensitivity • Hands-free, fast results 16×4 Cartridge 32×4 Cartridge 72×1 Cartridge Instrumentation: Ella™ Learn more | proteinsimple.com/ella 5 Immunoassay Offering by Molecule Luminex® Proteome Profiler® Luminex® Uncoated Coated Simple Plex™ Molecule High Performance Arrays Assays ELISA Kits ELISA Kits Assays Assays 4-1BB/TNFRSF9/CD137 H H M 14-3-3z H 20S Immunoproteasome H 25-OH Vitamin D H ACE/CD143 H H Acetylcholinesterase/ACHE H Activin A H H H M R ADAM8 H H ADAM9 H H ADAM10 H ADAM12 H H ADAM15 H H ADAMTS1 H M H ADAMTS4 H ADAMTS5 H ADAMTS13 H H H H Adiponectin/Acrp30 H M H M H H M R H M R H Afamin H Aggrecan H H Agrin R AgRP/ART H H H Akt, Phospho (S473) Pan Specific H M R Akt1 H H M R Akt1, Phospho (S473) H M Akt2 H Akt3 H Albumin H ALCAM/CD166 H M Aldehyde Dehydrogenase 1-A1/ H ALDH1A1 Aldosterone MS ALK-1 H M a1-Acid Glycoprotein H H a1B-Glycoprotein H a1-Microglobulin H a2-Macroglobulin H a-Defensin 1 H a-Fetoprotein/AFP H H M H M a-N-acetylglucosaminidase/ H NAGLU a-Synuclein H H AMICA/JAML H Aminoacylase/ACY1 H Aminopeptidase N/CD13 H H Amphiregulin H M H M H H AMPK a1 H M R AMPK a1, Phospho (T183) H Amyloid b H Amyloid b aa 1–42 H Angiogenin H M H H H H KEY Human H Mouse M Rat R Canine C Primate Pr Porcine P Multi-Species MS Viral V Bovine B C. botulinum Cb Cotton Rabbit CR Equine E Guinea Pig G Rabbit Rb *In Development 6 Learn more | rndsystems.com/immunoassays Luminex® Proteome Profiler® Luminex® Uncoated Coated Simple Plex™ Molecule High Performance Arrays Assays ELISA Kits ELISA Kits Assays Molecule Offering by Immunoassay Assays Angiopoietin-1 H M H H H H Angiopoietin-2 H M H M H H M R H Angiopoietin-3 M M Angiopoietin-4 H Angiopoietin-like 4 H Angiopoietin-like Protein 3/ H H M ANGPTL3 Angiopoietin-like Protein 4/ H H ANGPTL4 Angiopoietin-like Protein 6/ H H ANGPTL6 Annexin A2 H Annexin V H Apolipoprotein A-I/ApoA1 H H H Apolipoprotein B/ApoB H Apolipoprotein E/ApoE H APP H H H APRIL/TNFSF13 H H Artemin H H M ASC H ATF4 H Atrial Natriuretic Peptide/ANP H Attractin H H Axl H M H M H Axl, Phospho H B7-1/CD80 H M B7-H1/PD-L1 H H B7-H3 H H BACE-1 H H Bad H BAFF R/TNFRSF13C M BAFF/BLyS/TNFSF13B H M H H M H M H Bax H Bax-a H Bcl-2 H M H Bcl-10 H Bcl-x H M Bcl-xL H M BCMA/TNFRSF17 H H M H BDNF H H H M H H BDNF, Pro H b2-Microglobulin H H bIG-H3 H M b-Catenin H H Betacellulin/BTC H M b-NGF H M H R H Bikunin H BLC/BCA-1/CXCL13 H BMP-2 H H H M R H BMP-4 H H H H BMP-5 H BMP-6 H BMP-7 H H H KEY Human H Mouse M Rat R Canine C Primate Pr Porcine P Multi-Species MS Viral V Bovine B C. botulinum Cb Cotton Rabbit CR Equine E Guinea Pig G Rabbit Rb *In Development Learn more | rndsystems.com/immunoassays 7 Luminex® Proteome Profiler® Luminex® Uncoated Coated Simple Plex™ Molecule High Performance Arrays Assays ELISA Kits ELISA Kits Assays Assays BMP-9 H H M H BMP-10 H H M BoNT-A Cb BTLA H Butyrylcholinesterase/BCHE H H C1q R1/CD93 M H M CA15-3/MUC-1 H CA125/MUC16 H H H H Cadherin-11 H H Cadherin-13 H Cadherin-17 M Calbindin D H H H cAMP M R MS Carbonic Anhydrase IX/CA9 H H H H CARD6 H Cardiotrophin-1/CT-1 M Caspase-1 H H Caspase-3 H Caspase-3, Cleaved (Asp175) M H M Caspase-8 H Catalase H M Cathepsin A H Cathepsin B H H H Cathepsin B, Pro H Cathepsin D H Cathepsin E H Cathepsin L H H Cathepsin S H H H Cathepsin S, Pro H Cathepsin V H H Cathepsin X/Z/P H CBL H CCL1/I-309/TCA-3 H H M CCL2/JE/MCP-1 H M H H M R C H CCL3/MIP-1a H M H H M C H M H CCL4/MIP-1b H M H H M C H M H CCL5/RANTES H M H H M R H CCL6/C10 M CCL7/MCP-3/MARC H M H H H CCL8/MCP-2 H M H M H CCL9/10/MIP-1g M CCL11/Eotaxin H M H H M H M CCL12/MCP-5 M M M CCL13/MCP-4 H H H CCL14/HCC-1/HCC-3 H CCL14a/HCC-1 H CCL15/MIP-1d H H CCL16/HCC-4 H H CCL17/TARC H H M H CCL18/PARC H H H CCL19/MIP-3b H M H H M CCL20/MIP-3a H M H H M R H M H KEY Human H Mouse M Rat R Canine C Primate Pr Porcine P Multi-Species MS Viral V Bovine B C. botulinum Cb Cotton Rabbit CR Equine E Guinea Pig G Rabbit Rb *In Development 8 Learn more | rndsystems.com/immunoassays Luminex® Proteome Profiler® Luminex® Uncoated Coated Simple Plex™ Molecule High Performance Arrays Assays ELISA Kits ELISA Kits Assays Molecule Offering by Immunoassay Assays CCL21/6Ckine H M H M M CCL22/MDC H M H H M H M H CCL23/MPIF-1/Ckb8-1 H CCL24/Eotaxin-2/MPIF-2 H H M H CCL25/TECK H H M CCL26/Eotaxin-3 H H H CCL27/CTACK H H M H CCL28 H M H H M CD3e H CD5 H CD6 H CD8 H CD9 H CD14 H M H H H M H M H CD21/ Complement receptor H H type 2/CR2 CD23/Fce RII H H M H CD25/IL-2 Ra H H M H H CD27 Ligand/TNFSF7 M CD27/TNFRSF7 H H H M H CD28 H H CD30 Ligand/TNFSF8 M CD30/TNFRSF8 H H H M CD31/PECAM-1 H H CD36/SR-B3 H M CD38 H CD40 Ligand/TNFSF5 H H H H M H CD40/TNFRSF5 H H H H M H CD43 H CD44 H H CD44 s H CD47 H CD48/SLAMF2 H CD59 H CD97 H H CD99 H CD117/c-kit H H H CD117/c-kit, Phospho H CD163 H H H M H H CD200 H CD300a/LMIR1 H CDCP1 H CEACAM-1 H H H CEACAM-5/CD66e H H H H* CEACAM-6/CD66c H cGMP MS Chemerin H M H H M H M Chitinase 3-like 1 M H M H M H M H Chk2 (T68), Phospho H Chordin M Chorionic Gonadotropin b Chain H (HCG b) KEY Human H Mouse M Rat R Canine C Primate Pr Porcine P Multi-Species MS Viral V Bovine B C. botulinum Cb Cotton Rabbit CR Equine E Guinea Pig G Rabbit Rb *In Development Learn more | rndsystems.com/immunoassays 9 Luminex® Proteome Profiler® Luminex® Uncoated Coated Simple Plex™ Molecule High Performance Arrays Assays ELISA Kits ELISA Kits Assays Assays Chromogranin A H H cIAP-1 H cIAP-2 H Cited-2 H Claspin H M CLEC-1 H CLEC-2 H Clusterin H H M H M CNTF R H R H Coagulation Factor III H (Tissue Factor)/CD142 Coagulation Factor XIV/Protein C H COCO H Collagen I a1 H H Collagen II, Pro H Collagen IV a1/COL4A1 H Common g Chain/IL-2 Rg H COMP/Thrombospondin-5 H H H Complement Component C2 H Complement Component C3a H Complement Component C5/C5a H M H H M Complement Component C9 H Complement Factor D/Adipsin H M H M H H M H Complement Factor H H Contactin-1 H Contactin-2/TAG1 H Corin H H Corticosterone MS Cortisol MS COX-2 H H M C-Peptide H C-Reactive Protein/CRP H H M H H M H Creatinine MS CREB H CREB (S133), Phospho H M R c-Rel H CRELD2 H Cripto H H CRISP-1 M CRTAM H H CTGF/CCN2 H CTLA-4 M CTRP3/C1qTNF3/CORS26 H CTRP9/C1qTNF9 H CX3CL1/Fractalkine H H H M R H M H CXCL1/GROa/KC/CINC-1 H M H H M R H M R CXCL2/GROb/MIP-2/CINC-3 H M R H H M R M R CXCL3/GROg/CINC-2/DCIP-1 R R R CXCL4/PF4 H H M H M CXCL5/ENA-78 H H H H H CXCL6/GCP-2 H H H CXCL7/NAP-2 H H KEY Human H Mouse M Rat R Canine C Primate Pr Porcine P Multi-Species MS Viral V Bovine B C.