Influenza Virus Non-Structural Protein NS1 Cooperatively Binds Virus-Specific (+)-Strand RNA Sequences Daniel Marc, Denis Soubieux

Influenza Virus Non-Structural Protein NS1 Cooperatively Binds Virus-Specific (+)-Strand RNA Sequences Daniel Marc, Denis Soubieux

Influenza virus non-structural protein NS1 cooperatively binds virus-specific (+)-strand RNA sequences Daniel Marc, Denis Soubieux To cite this version: Daniel Marc, Denis Soubieux. Influenza virus non-structural protein NS1 cooperatively binds virus- specific (+)-strand RNA sequences. 15. International Conference on Negative Strand Viruses (NSV 2013), Jun 2013, Grenade, Spain. hal-02744878 HAL Id: hal-02744878 https://hal.inrae.fr/hal-02744878 Submitted on 3 Jun 2020 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. 1 The front cover shows a middle optical section of MDCK cells infected with Sendai virus in the process of forming a limited syncytium. The red stain corresponds to the nucleocapsid protein and the greento a M protein mutated so it does not reach the cell plasma membrane. The nuclei are colored with DAPI. 2 15th International Negative Strand Virus Meeting NSV 2013 16 - 21 June 2013, Granada, Spain 3 4 Table of Contents General information ...................................................................... 4 Social programme ...........................................................................5 Program sumary ..............................................................................6 Programe ..........................................................................................9 Abstracts ..........................................................................................45 Authors .........................................................................................223 Registered participants ...............................................................237 5 General Information: Badges All participants and accompanying persons must wear the oficial badges in order to get Access to the lecture halls and/or social activities. Official Language The official language of the Conference is English. Simultaneous translation will not be provided. Audiovisuals All presentations are to be uploaded in the conference room. Hand in your PowerPoint presentations to the technicians at least one hour before your talk . Poster Presentations Posters in sessions I to V: These posters are to be mounted between 14.00 hrs and 19.00 hrs on Sunday afternoon, June 16. These posters are to be removed during the morning coffee break ( 11:30- 12:30 ) on Wednesday, June 19. Posters in Sessions VI to VIII : These posters are to be mounted during the lunch break ( 13:50 – 15:20) on Wednesday, June 19. These posters are to removed between 12:00 and 14:00 on Friday , June 21. Conference Documents Participants will receive a badge , a certificate of attendance and a conference bag with conference- related documents at the registration desk. Meals Lunches will be provided in the Palacio de Congresos , as indicated in the programme. Evening meals will be provided as part of the social programme. The cost of these are included in the registration fee. Non-Smoking Policy In Spain you are only allowed to smoke outside buildings. Granada’s city buses general information Granada’s urban bus network is managed by the Transportes Rober bus company. Bus network maps, timetables, fares, and also buses to the Alhambra and Albayzin etc are available on Granada’s city buses such. Granada’s taxis You can find taxis at exit of bus stations, trains and airports. Granada is a small city, and it is easy to get around, taxis are not very expensive. Tele - Radio - Taxi Granada Telephone: +34 958 28 06 54 Radio Taxi Company: Telephone: +34 958 13 23 23 Spanish timing and habits 6 Breakfast: Between 8am - 10am Lunch: Kitchen service is usually open in restaurants between 1pm - 4pm, although some offer food even earlier Dinner: Usually from 8.30pm until 11pm Climate The climate in Granada is Continental Mediterranean. Temperatures are fresh in Winter, and hot in summertime, reaching maximuns above 35ºC (95ºF). Check the weather in the Spanish Agency of Meteorology Social Programme Opening Reception on Sunday , June 16 The Opening Reception will take place at Palacio de Congresos at 20.00 hrs. social programme Address : Walking Guided Tour of Granada on Monday , June 17. And free evening. The walking tour will start from the Palacio de Congresos at 19.30 hrs. And will end at approx 21.00 hrs. Alhambra’s visit + dinner in the gardens overlooking Granada by night. The Alhambra visit start from Palacio de Congresos at 19.30 hrs. Gala Dinner on Thursday , June 20 The Gala Dinner will take place in “La Mamounia”. Buses start from Palacio de Congre- sos at 20.00 hrs. 7 Program Sumary: Sunday June 16 14:00 - 19 :00 Registration Palacio de Congresos, Put up posters for sessions 1-4 19:00-23 :00 Opening reception Palacio de Congresos 20:00 Flamenco concert: roof of Palacio de Congresos Monday June 17 09:45-10:00: Welcome and introductory information Session I:In and Out and Moving About (10:10- 13:50) 10:00 -10:10 Chairpersons’s remarks 11:30 -12:30 Coffee break-Poster session 13:50 -15:20 Lunch- Poster session Session II: RNA synthesis and gene expression (15:30-18:50) 15:20-15:30: Chairpersons’s remarks 16:50 -17 :50 Coffee break-Poster session 19:30 Guided tour of Granada and free evening Tuesday June 18 Session III:Structure and Function ( 10:10-13:50) program sumary program 10:00-10:10: Chairpersons’s remarks 11:30 -12 :30 Coffee break-Poster session 13:50-15:20 Lunch- Poster session Session IV:Host-cell interactions (15:30-19:10) 15:20-15:30: Chairpersons’s remarks 16:50 -17 :50 Coffee break-Poster session 20:00 Alhambra’s visit + dinner in the gardens overlooking Granada by night Wednesday June 19 09:00-10:00 Put up posters for sessions V-VIII Session V: Antiviral response (10:10-13:50) 8 10:00-10:10: Chairpersons’s remarks 11:30 -12:30 Coffee break-Poster session 13:50-15:20 Lunch- Poster session Session VI: Pathogenesis (15:30-19:00) 15:20-15:30 Chairpersons’s remarks 17:00 -18:00 Coffee break-Poster session Free evening Thursday June 20 Session VII: Vaccines and antivirals (10:10-13:20) sumary program 10:00-10:10: Chairpersons’s remarks 11:30 -12 :30 Coffee break-Poster session 13:20-15:00 Lunch- Poster session Session VII:Vaccines and antivirals continued (15:10-17:50) 15:00-15:10 Chair persons’s remarks 16:10 -17 :10 Coffee break-Poster session 20:00 Gala dinner . Friday June 21 Session VIII: Natural and unnatural virus evolution (09:10-12:10) 09:00 - 09:10 Chair persons’s remarks 10:00 -11 :00 Coffee break-Poster session 12:10 Lunch and beer session 9 Program Sunday June 16 14:00- 19 :00 Registration Palacio de Congresos, Put up posters for sessions 1-4 19:00-23 :00 Opening reception Palacio de Congresos 20:00 Flamenco concert: roof of Palacio de Congresos 10 Monday June 17 09:45-10:00: Welcome and introductory information Session I:In and Out and Moving About Chairpersons :Christina Spirolopulo and Benhur Lee 10:00-10 :10:Chairpersons’s remarks 10:10-10:30 1 Fusion activation by parainfluenza virus HN protein Sayantan Bose, Theodore S. Jardetzky and Robert A. Lamb 10:30-10:50 2 Unraveling a 3-step Mechanism of Nipah Virus Receptor- Induced Membrane FusionTriggering Qian Liu, Jacqueline A. Stone, Birgit Bradel-Tretheway, Jeffrey Dabundo, Javier A. Benavides, Montano, Jennifer Santos- Montanez, Scott B. Biering1, Xiaonan Lu, Hector C. Aguilar 10:50-11 :10 3 PVRL4 (Nectin-4) is the epithelial cell for measles and canine distemper viruses and is a target for oncolytic therapy Christopher Richardson, Ryan Noyce, SebastienDelpeut, Ricky Siu programe 11:10-11:20 4 The measles virus hemagglutininβ4-β5 hydrophobic groove governs the interactions with nectin-4 and CD46 but not with SLAM Mathieu Mateo, Sabriya Syed, ChanakhaNavaratnarajah, Roberto Cattaneo 11:20-11:30 5 Conversion of the parainfluenza virus 5 F protein to a simian virus 41 HN-specific protein by amino acid substitutions Talk Masato Tsurudome , Morihiro Ito , MachikoNishio, Tetsuya Nosaka 11:30 -12 :30 Coffee break-Poster session 12:30-12:50 6 Vesiculovirus glycoprotein intermediate structures during the fusion associated conformational change. Talk Eduard Baquero , Aurélie A. Albertini , MalikaOuldali, Linda Buonocore , John K. Rose , Jean Lepault, Stéphane Bressanelli, Yves Gaudin 12:50-13:00 7 Host cell entry of Respiratory Syncytial Virus involves macropinocytosis followed by proteolytic activation of the F protein Magdalena Krzyzaniak, Ari Helenius 13:00-13:10 8 Acid-activated structural reorganization of the Rift Valley fever virus Gc fusion protein Matthijn de Boer, Jeroen Kortekaas, LotteSpel, Peter Rottier, Rob Moormann, Berend Jan Bosch’ 13:10-13:20 9 Insights into transport of Marburg virus nucleocapsids in living cells Schudt Gordian, Kolesnikova Larissa, Dolnik Olga, Becker Stephan 11 13:20-13:30 10 Essential role of the Sendai virus fusion (F) protein in the formation of virus particles Manel Essaidi-Laziosi, Anastasia Shevtsova, Carole Bampi, Laurent Roux 13:30-13:40 11 Orientations of the influenza A viral ribonucleoprotein complexes Yukihiko Sugita, Hiroshi Sagara, Takeshi Noda, Yoshihiro Kawaoka 13:40-13:50 12 Diverse Morphologies of Influenza Filament Budding: an Ultrastructural

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