Test Catalog 09/19/2021 OU MEDICAL CENTER Laboratory offers a listing of the clinical tests, as well as information regarding turn-around times, specimen requirements, reference ranges, patient requirements, etc in this test catalog. Microbiology testing follows the clinical listing. The test catalog is fully searchable via Adobe Reader's search functions (Adobe 5 or higher required). To search online for a test, click on the Search icon in the Adobe Reader Toolbar area....it looks like a pair of binoculars. Type the word or portion of the word that you would like to find and press the Enter key. Contact the Laboratory at (405)271-3260 to obtain further information. [11BPGD2U] Ur 11 beta-Prostaglandin F2 alpha SPECIMEN REQUIRED: Refrigerated or frozen urine (24-hour (collection) TUBE OR CONTAINER: Plastic urine container SPECIAL HANDLING: Collect 24-hour urine in "D" container (6N HCl) SPECIMEN VOLUME: 5 mL MINIMUM VOLUME: 1 mL TEST AVAILABILITY: Daily TURNAROUND TIME: 3-7 days REFERENCE RANGE: < 1382 pg/mg creatinine METHODOLOGY: Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) AACT: Enzymatic Colorimetric Assay CPT: 84150 [17HCS] UR 17 HYDROXYCORTICOSTEROIDS SPECIMEN REQUIRED: Frozen urine (24 hour collection) TUBE OR CONTAINER: Plastic urine container acid) or "P" container (no preservative). All drugs should be withheld for 72 hours prior to collection, if possible Sample pH must be between 5.0-7.0 SPECIMEN VOLUME: 12 mL MINIMUM VOLUME: 6 mL TEST AVAILABILITY: Daily TURNAROUND TIME: 4-8 days REFERENCE RANGE: 2.0-6.5 mg/g creatinine 4.0-14.0 mg/day OTHER NAMES: 17-OHCS, Urine; Porter-Silber Chromogens, Urine METHODOLOGY: Quantitative Colorimetry CLINICAL USE: Adrenal function test useful in evaluation of glucocorticoid production; increased in ectopic ACTH syndrome, Cushing syndrome and stress; decreased in Addison's disease, adrenogenital syndrome, pituitary insufficiency CPT: 83941 [17HYD] 17-Hydroxyprogesterone SPECIMEN REQUIRED: Refrigerated serum or plasma TUBE OR CONTAINER: Red, Gold or Lavender (EDTA) SPECIMEN VOLUME: 1 mL MINIMUM VOLUME: 0.5 mL (this volume does not allow for repeat testing) PEDIATRIC TEST INFO: Order PED17HYD for pediatric testing to be performed by Esoterix TEST AVAILABILITY: Daily TURNAROUND TIME: 2-3 days REFERENCE RANGE: Age-specific METHODOLOGY: Liquid chromatography/tandem mass spectrometry (LC/MS-MS) CLINICAL USE: Markedly elevated in patients with congenital adrenal hyperplasia (adrenogenital syndrome) due to 21-hydroxylase deficiency; evaluate hirsutism and/or infertility; assess certain adrenal or ovarian tumors with endocrine activity CPT: 83498 [17KET24] UR 17 KETOSTEROIDS TOTAL SPECIMEN REQUIRED: Refrigerated or frozen urine (24 hour collection), random sample is acceptable TUBE OR CONTAINER: Plastic urine container SPECIAL HANDLING: Collect urine in "P" or "D" container (30mLs 6N HCL) Refrigerate during collection; Final pH must be 2-4 SPECIMEN VOLUME: 5 mL MINIMUM VOLUME: 3 mL TEST AVAILABILITY: Daily TURNAROUND TIME: 3-7 days REFERENCE RANGE: 0-11 months: 0.0-1.0 mg/d 1-5 years: 1.0-2.0 mg/d 6-10 years: 1.0-4.4 mg/d (male) 1.4-3.9 mg/d (female) 11-12 years: 1.3-8.5 mg/d (male) 3.5-9.5 mg/d (female) 13-16 years: 3.4-9.8 mg/d (male) 4.5-17.1 mg/d (female) 17-50 years: 5.3-17.6 mg/d (male) 4.4-14.2 mg/d (female) 51 years and older: 4.1-12.1 mg/d (male) 3.2-10.6 mg/d (female) METHODOLOGY: Quantitative Spectrophotometry (Zimmerman) CLINICAL USE: Assess adrenal androgens CPT: 82570; 83586 [17OHPREG] 17-Hydroxy-Pregnenolone SPECIMEN REQUIRED: Frozen serum or plasma TUBE OR CONTAINER: Red, Gold or Lavender (EDTA) SPECIMEN VOLUME: 1 mL SPECIMEN VOLUME: 1 mL MINIMUM VOLUME: 0.3 mL (this volume does not allow for repeat testing) PEDIATRIC TEST INFO: Order PED17OHP for pediatric testing to be performed by Esoterix TEST AVAILABILITY: Daily REFERENCE RANGE: Male: 10-100 ng/dL Female: 10-250 ng/dL METHODOLOGY: Radioimmunoassay (RIA) CPT: 84143 [1P19QFISH] 1p & 19q IN SITU HYBRIDIZATION SPECIMEN REQUIRED: Formalin-fixed, paraffin-embedded (FFPE) tissue biopsy at room temperature or Unstained slides and H&E TUBE OR CONTAINER: Slides or blocks SPECIMEN VOLUME: 6 unstained slides and 1 H&E stained side at 10 uM or tissue block TEST AVAILABILITY: Daily METHODOLOGY: In situ hybridization CPT: 88368 x 4 [21HYDAB] 21-Hydroxylase Antibody SPECIMEN REQUIRED: Frozen serum or plasma TUBE OR CONTAINER: Red, Gold or Lavender (EDTA) SPECIAL HANDLING: Separate serum or plasma from cells within 1 hour of collection SPECIMEN VOLUME: 1 mL MINIMUM VOLUME: 0.2 mL TEST AVAILABILITY: Daily TURNAROUND TIME: 2-9 days METHODOLOGY: Radioimmunoassay Immunoprecipitation CLINICAL USE: Investigation of adrenal insufficiency; Aid in the detection of those at risk of developing autoimmune adrenal failure in the future CPT: 83519 [23DINOR] 11 beta-Prostaglandin F2 alpha [5FLUOR] 5-Fluorocytosine Level SPECIMEN REQUIRED: Refrigerated serum or plasma TUBE OR CONTAINER: Red (no gel) or Lavender (EDTA) SPECIMEN VOLUME: 1 mL MINIMUM VOLUME: 0.3 mL TEST AVAILABILITY: Daily TURNAROUND TIME: 7-10 days OTHER NAMES: 5FC; 5-Fluorouracil; 5-Fluorocytosine Ancobon Flucytosine METHODOLOGY: High Performance Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS) CPT: 80299 [5HIAA] UR HYDROXYINDOLEACETIC ACID QT SPECIMEN REQUIRED: Room temperature urine (24-hour collection) TUBE OR CONTAINER: Plastic urine container SPECIAL HANDLING: 24 hour urine collected in "P" container (no preservative); boric acid may be added as a preservative for other tests without harm to 5-HIAA however, pH can not be less than 2 SPECIMEN VOLUME: 30 mL MINIMUM VOLUME: 1 mL TEST AVAILABILITY: Daily TURNAROUND TIME: 2 days REFERENCE RANGE: 0.0-14.9 mg/24 hours OTHER NAMES: Serotonin Metabolite, Urine METHODOLOGY: Liquid chromatography/Tandem Mass Spectrometry (LC-MS/MS) CLINICAL USE: 5-HIAA is the major urinary metabolite of serotonin; both are produced in excess by most carcinoid tumors CPT: 83947 [5HIAARAN] HYDROXYINDOLEACETIC ACID RANDO SPECIMEN REQUIRED: Room temperature urine (random) TUBE OR CONTAINER: Plastic urine container SPECIAL HANDLING: Plastic urine container, no preservative. (Note: Boric acid may be added as a preservative for other tests without harm to 5-HIAA.) SPECIMEN VOLUME: 1 mL MINIMUM VOLUME: 0.3 mL TEST AVAILABILITY: Daily TURNAROUND TIME: 2-3 days REFERENCE RANGE: Pediatrics: 0-3 years: 0.0-16.2 mg/g creatinine 9-12 years: 0.0-8.7 mg/g creatinine 13-18 years: 0.0-5.5 mg/g creatinine > 18 years: 0.0-6.9 mg/g creatinine METHODOLOGY: Liquid chromatography/Tandem Mass Spectrometry (LC-MS/MS) CLINICAL USE: 5 -HIAA is the major urinary metabolite of serotonin; both are produced in excess by most carcinoid tumors CPT: 82570; 83947 [A1APH] ALPHA 1 ANTITRYPSIN PHENOTYPIN SPECIMEN REQUIRED: Room Temp serum; overnight fast preferred TUBE OR CONTAINER: Red or gold SPECIMEN VOLUME: 2 mL MINIMUM VOLUME: 1 mL TEST INCLUDES: Alpha-1-Antitrypsin, total; and phenotype TEST AVAILABILITY: Daily TURNAROUND TIME: 1-2 days REFERENCE RANGE: Interpretation accompanies report OTHER NAMES: A1A Phenotyping; A1AT Phenotype; AAT Phenotype; Pi Phenotype; Protease Inhibitors METHODOLOGY: Phenotype: Isoelectric Focusing (IEF) Total: Immunologic CLINICAL USE: Definitive analysis of hereditary alpha-1- antitrypsin deficiency, which is associated with chronic obstructive pulmonary disease (COPD) (panacinar emphysema), hepatic cirrhosis, and hepatoma CPT: 82103; 82104 [A1ASTL] Stool Alpha-1-Antitrypsin SPECIMEN REQUIRED: Frozen stool TUBE OR CONTAINER: Screw-cap container SPECIMEN VOLUME: 5 gram MINIMUM VOLUME: 1 gram TEST AVAILABILITY: Daily TURNAROUND TIME: 2-4 days REFERENCE RANGE: < 0.62 mg/g METHODOLOGY: Radial Immunodiffusion CPT: 82103 [A1GLY] Alpha-1-Acid Glycoprotein SPECIMEN REQUIRED: Frozen serum TUBE OR CONTAINER: Red or gold CAUSE FOR REJECTION: Gross lipemia that cannot be cleared by ultracentrifugation SPECIMEN VOLUME: 1 mL MINIMUM VOLUME: 0.5 mL TEST AVAILABILITY: Daily TURNAROUND TIME: 3-5 days REFERENCE RANGE: 18 years and older: 50-120 mg/dL METHODOLOGY: Immunologic CLINICAL USE: Decreased serum levels may be found in association with malnutrition, severe liver damage, and in women using estrogen-related oral contraceptives. Increased levels have been reported in conditions of acute and chronic inflammation, including myocardial infarction, rheumatoid arthritis, systemic lupus erythematosus, and malignancy CPT: 82985 [ACCEL] Accelerate Pheno Test [ACE] Angiotensin Converting Enzyme SPECIMEN REQUIRED: Refrigerated serum TUBE OR CONTAINER: Red or Gold icteric sample SPECIMEN VOLUME: 1 mL MINIMUM VOLUME: 0.5 mL TEST AVAILABILITY: Daily TURNAROUND TIME: 48 hours REFERENCE RANGE: 0-2 years: 18-95 units/L 3-14 years: 22-108 units/L 15 years or older: 14-82 units/L METHODOLOGY: Kinetic CLINICAL USE: High in sarcoidosis, more often when the disease is active; assessment of the response of sarcoidosis to corticosteroid therapy CPT: 82164 [ACECSF] CSF Angiotensin Converting Enzyme SPECIMEN REQUIRED: Frozen CSF TUBE OR CONTAINER: Sterile conical/capped tube SPECIMEN VOLUME: 0.5 mL MINIMUM VOLUME: 0.2 mL TEST AVAILABILITY: Daily TURNAROUND TIME: 3-7 days REFERENCE RANGE: 0.0-2.5 U/L METHODOLOGY: Spectrophotometry CLINICAL USE: May be used to support the diagnosis of sarcoidosis or neurosarcoidosis CPT: 82164 [ACET] Acetaminophen Level SPECIMEN REQUIRED: Refrigerated plasma or serum TUBE OR CONTAINER: Light Green (heparin) or Gold SPECIAL HANDLING: When evaluating for possible toxicity, a 4 to 6 post-ingestion sample should be drawn Collect a second sample