Vardenafil Better Choice for Premature Ejaculation

Vardenafil Better Choice for Premature Ejaculation

August 15, 2005 • www.familypracticenews.com Men’s Health 47 Vardenafil Better Choice for Premature Ejaculation BY ROBERT FINN (24%) of the men and was secondary (in On a self-rating scale of 0-8, where 0 Center but is now at the University of San Francisco Bureau most cases to erectile dysfunction) in the means PE almost never, 4 means PE about Hamburg. remaining 26 men (77%). half the time, and 8 means PE almost al- Self-ratings of sexual satisfaction, on a 0- S AN A NTONIO — Vardenafil improved After a 4-week run-in period, 17 men ways, the mean score was 6.14 at baseline, 5 scale, where 0 means not at all satisfied premature ejaculation more than sertra- were given 10-mg vardenafil 10 minutes 4.28 with sertraline, and 3.2 with varde- and 5 means extremely satisfied, averaged line, Frank Sommer, M.D., reported at the before intercourse for 6 weeks. The other nafil. 1.4 at baseline, 3.2 with sertraline, and 4.2 annual meeting of the American Urolog- 17 received 50 mg of sertraline 4 hours be- IVELT, as measured by a stopwatch, with vardenafil. In addition, the partners’ ical Association. fore intercourse. averaged 0.54 minutes at baseline, 2.87 sexual satisfaction showed significant in- Both vardenafil (Levitra), a phosphodi- After a 1-week washout period, the men minutes with sertraline, and 5.23 minutes creases for sertraline and even more so for esterase-5 inhibitor, and sertraline (Zoloft), who had been receiving sertraline with vardenafil, reported Dr. Sommer, vardenafil. a selective serotonin reuptake inhibitor, re- switched to vardenafil and vice versa for who conducted the research at the Dr. Sommer stated that he had no con- sulted in significant improvements in sev- an additional 6 weeks. Cologne (Germany) University Medical flicts of interest related to his study. ■ eral measures of premature ejaculation (PE) over baseline, but vardenafil proved significantly better than sertraline on all measures. The relatively small, crossover study in- #1 RECOMMENDED METER* volved 34 heterosexual men who report- ed PE more than half the time and who had intravaginal ejaculatory latency times (IVELT) of less than 1.5 minutes at base- line. PE was the primary complaint in 8 FDA: Vision Loss Reported With ED Drug Use he Food and Drug Administration has Tapproved revised labeling for Cialis (tadalafil), Levitra (vardenafil), and Viagra (sildenafil) to reflect a small number of postmarketing reports of sudden vision loss. The sudden loss of eyesight is attributed to nonarteritic ischemic optic neuropathy, in which blood flow is blocked to the op- tic nerve. It’s not known if these erectile dysfunction medications cause this condi- tion. People with a higher chance of de- veloping this condition include those who: Ǡ Have heart disease. Ǡ Are older than 50 years. Ǡ Have diabetes. Ǡ Have high blood pressure. Ǡ Have high cholesterol. Ǡ Smoke. Ǡ Have certain eye problems. Patients taking these medications are advised to discontinue use and contact their physician immediately if they expe- rience sudden vision loss or decreased vi- sion in one or both eyes. In addition, pa- tients taking or considering these products UNLESS HE TESTS WITH ONETOUCH® ULTRA.® should inform their physician if they have ever had severe loss of vision, which could The blues are in his blood. Fortunately, OneTouch® Ultra® requires so little that B.B. reflect a prior episode of nonarteritic is- can also test on his arm† when he wants to save those sensitive fingers for what they chemic optic neuropathy. Such patients do best. Either way, he’ll get a less painful test** with results in just five seconds. have an increased risk of developing the condition again. Less pain. Less blood. Less time. More compliance. For additional information about la- More info? Call 1-800-524-7226 or visit www.LifeScan.com. beling changes to Cialis, visit www.fda. gov/cder/drug/infopage/cialis/ default.htm. For additional information about la- beling changes to Levitra, visit www.fda. gov/cder/drug/infopage/vardenafil/ default.htm. *Recommended by Diabetologists, Endocrinologists, Diabetes Educators, and Pharmacists, PET Tracking Study, Fall 2002. †Whenting ontes the arm, patients should read the owner’s booklet and talk to their healthcare professional. **Allows for a less painful stick when used with OneTouch® UltraSoft® Adjustable Blood Sampler For additional information about la- and OneTouch® UltraSoft® Lancets. © 2005 LifeScan, Inc. Milpitas, CA 95035 1/05 AW 058-882B beling changes to Viagra, visit www. fda.gov/cder/consumerinfo/Viagra/ Viagra.htm. —Kerri Wachter.

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