Anti-KIF20A monoclonal antibody (DCABH-15860) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Antigen Description Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along. Immunogen A synthetic peptide of human KIF20A is used for rabbit immunization. Isotype IgG Source/Host Rabbit Species Reactivity Human Purification Protein A Conjugate Unconjugated Applications Western Blot (Transfected lysate); ELISA Size 1 ea Buffer In 1x PBS, pH 7.4 Preservative None Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. GENE INFORMATION Gene Name KIF20A kinesin family member 20A [ Homo sapiens ] Official Symbol KIF20A Synonyms KIF20A; kinesin family member 20A; RAB6 interacting, kinesin like (rabkinesin6) , RAB6KIFL; kinesin-like protein KIF20A; GG10_2; rabkinesin-6; mitotic kinesin-like protein 2; rab6-interacting kinesin-like protein; RAB6 interacting, kinesin-like (rabkinesin6); MKLP2; RAB6KIFL; FLJ21151; Entrez Gene ID 10112 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Protein Refseq NP_005724 UniProt ID O95235 Chromosome Location 5q31 Pathway Aurora B signaling, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; DNA Replication, organism-specific biosystem; Factors involved in megakaryocyte development and platelet production Function ATP binding; microtubule motor activity; nucleotide binding; protein kinase binding; transporter activity; 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved.