Safety Data Sheet according to 29CFR1910/1200 and GHS Rev. 3 Effective date : 12.22.2014 Page 1 of 8 Acetic Anhydride SECTION 1 : Identification of the substance/mixture and of the supplier Product name : Acetic Anhydride Manufacturer/Supplier Trade name: Manufacturer/Supplier Article number: S25119A Recommended uses of the product and uses restrictions on use: Manufacturer Details: AquaPhoenix Scientific 9 Barnhart Drive, Hanover, PA 17331 Supplier Details: Fisher Science Education 15 Jet View Drive, Rochester, NY 14624 Emergency telephone number: Fisher Science Education Emergency Telephone No.: 800-535-5053 SECTION 2 : Hazards identification Classification of the substance or mixture: Flammable Flammable liquids, category 3 Irritant Acute toxicity (oral, dermal, inhalation), category 4 Acute toxicity (oral, dermal, inhalation), category 3 Corrosive Skin corrosion, category 1B Serious eye damage, category 1 Flam Liq. 3 AcTox Oral 4 AcTox Inhaln 4 Skin corr. 1B Eye. Damage 1 Signal word :Danger Hazard statements: Flammable liquid and vapour Harmful if swallowed Causes severe skin burns and eye damage Causes serious eye damage Toxic if inhaled Precautionary statements: If medical advice is needed, have product container or label at hand Keep out of reach of children Read label before use Created by Global Safety Management, Inc. -Tel: 1-813-435-5161 - www.gsmsds.com Safety Data Sheet according to 29CFR1910/1200 and GHS Rev. 3 Effective date : 12.22.2014 Page 2 of 8 Acetic Anhydride Keep container tightly closed Do not eat, drink or smoke when using this product Wash skin thoroughly after handling Avoid breathing dust/fume/gas/mist/vapours/spray Keep away from heat/sparks/open flames/hot surfaces. No smoking Ground/bond container and receiving equipment Use explosion-proof electrical/ventilating/light/…/equipment Use only non-sparking tools Take precautionary measures against static discharge Use only outdoors or in a well-ventilated area Wear protective gloves/protective clothing/eye protection/face protection IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing Immediately call a POISON CENTER or doctor/physician IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing Immediately call a POISON CENTER or doctor/physician Wash contaminated clothing before reuse In case of fire: Use agents recommended in section 5 for extinction IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell Rinse mouth IF SWALLOWED: Rinse mouth. Do NOT induce vomiting Store in a well ventilated place. Keep cool Store locked up Store in a well ventilated place. Keep container tightly closed Dispose of contents and container as instructed in Section 13 Other Non-GHS Classification: WHMIS B3 D1A E NFPA/HMIS Created by Global Safety Management, Inc. -Tel: 1-813-435-5161 - www.gsmsds.com Safety Data Sheet according to 29CFR1910/1200 and GHS Rev. 3 Effective date : 12.22.2014 Page 3 of 8 Acetic Anhydride NFPA SCALE (0-4) HMIS RATINGS (0-4) SECTION 3 : Composition/information on ingredients Ingredients: CAS 108-24-7 Acetic Anhydride 100 % Percentages are by weight SECTION 4 : First aid measures Description of first aid measures After inhalation: Move exposed individual to fresh air. Loosen clothing as necessary and position individual in a comfortable position.Seek medical advice if discomfort or irritation persists.Give artificial respiration if necessary. If breathing is difficult, give oxygen. After skin contact: Rinse exposed skin with water for 20 minutes.Immediately enter emergency shower rinsing while removing contaminated clothing and shoes.Transport victim to the hospital. After eye contact: Protect unexposed eye. Flush exposed eye gently using water for 15-20 minutes.Remove contact lenses while rinsing.Immediately seek medical attention. After swallowing: Rinse mouth thoroughly. Do not induce vomiting. Dilute with water or milk.Immediately seek medical attention. Most important symptoms and effects, both acute and delayed: Irritation, Nausea,Headache, Shortness of breath.; Indication of any immediate medical attention and special treatment needed: If seeking medical attention, provide SDS document to physician.Physician should treat symptomatically. SECTION 5 : Firefighting measures Extinguishing media Suitable extinguishing agents: Use water, dry chemical, chemical foam, carbon dioxide, or alcohol-resistant foam.Use water spray to cool unopened containers. For safety reasons unsuitable extinguishing agents: Special hazards arising from the substance or mixture: Thermal decomposition may lead to release of irritating gases and vapor. Advice for firefighters: Protective equipment: Wear protective eyeware, gloves, and clothing. Refer to Section 8. Additional information (precautions): SECTION 6 : Accidental release measures Personal precautions, protective equipment and emergency procedures: Ensure adequate ventilation.Ensure that air-handling systems are operational.Use explosion - proof equipment. Environmental precautions: Prevent from reaching drains, sewer or waterway. Should not be released into environment. Methods and material for containment and cleaning up: Wear protective eyeware, gloves, and clothing. Refer to Section 8.Always obey local regulations.If necessary use trained response staff or contractor. Evacuate personnel to safe areas. Containerize for disposal. Refer to Section 13.Keep in suitable closed containers for disposal. Created by Global Safety Management, Inc. -Tel: 1-813-435-5161 - www.gsmsds.com Safety Data Sheet according to 29CFR1910/1200 and GHS Rev. 3 Effective date : 12.22.2014 Page 4 of 8 Acetic Anhydride Reference to other sections: SECTION 7 : Handling and storage Precautions for safe handling: Wear protective eyeware, gloves, and clothing. Refer to Section 8.Always obey local regulations.If necessary use trained response staff or contractor. Evacuate personnel to safe areas. Containerize for disposal. Refer to Section 13.Keep in suitable closed containers for disposal.Keep away from open flames, hot surfaces and sources of ignition. Conditions for safe storage, including any incompatibilities: Avoid contact with skin, eyes, and clothing.Follow good hygiene procedures when handling chemical materials. Refer to Section 8.Follow proper disposal methods. Refer to Section 13.Do not eat, drink, smoke, or use personal products when handling chemical substances. SECTION 8 : Exposure controls/personal protection Control Parameters: 108-24-7, Acetic Anhydride , NIOSH 5 ppm Ceiling; 20 mg/m3 Ceiling 108-24-7, Acetic Anhydride , NIOSH 200 ppm IDLH 108-24-7, Acetic Anhydride , ACGIH 3 ppm STEL; 1 ppm TWA Appropriate Engineering controls: Emergency eye wash fountains and safety showers should be available in the immediate vicinity of use/handling.Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapor and mists below the applicable workplace exposure limits (Occupational Exposure Limits-OELs) indicated above. Respiratory protection: Not required under normal conditions of use. Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls.When necessary use NIOSH approved breathing equipment. Protection of skin: Select glove material impermeable and resistant to the substance.Select glove material based on rates of diffusion and degradation.Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.Use proper glove removal technique without touching outer surface. Avoid skin contact with used gloves.Wear protective clothing. Eye protection: Safety glasses with side shields or goggles.Wear equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). General hygienic measures: Perform routine housekeeping.Wash hands before breaks and immediately after handling the product.Avoid contact with skin, eyes, and clothing.Before rewearing wash contaminated clothing. SECTION 9 : Physical and chemical properties Appearance (physical Explosion limit lower: 2.7 %(V) Clear, colorless liquid. state,color): Explosion limit upper: 10.3 %(V) Created by Global Safety Management, Inc. -Tel: 1-813-435-5161 - www.gsmsds.com Safety Data Sheet according to 29CFR1910/1200 and GHS Rev. 3 Effective date : 12.22.2014 Page 5 of 8 Acetic Anhydride Odor: Vinegar-like Vapor pressure: 5 hPa at 20 °C Odor threshold: Not Determined Vapor density: 3.52 - (Air = 1.0) pH-value: Not Determined Relative density: 1.08 g/cm3 Melting/Freezing point: -73 °C Solubilities: Soluble in water Boiling point/Boiling Partition coefficient (n- 137 °C log Pow : ca. - 0.27 range: octanol/water): Flash point (closed Auto/Self-ignition 52 °C 316 °C cup): temperature: Decomposition Evaporation rate: 0.46 Not Determined temperature: Flammability a. Kinematic:Not Determined Flammable Viscosity: (solid,gaseous): b. Dynamic: Not Determined Density: Not Determined SECTION 10 : Stability and reactivity Reactivity:Reacts violently with water. Chemical stability:May decompose if exposed to moist air or water. Substance is readily hydrolyzed. Reacts with water to form corresponding acid. Possible hazardous reactions: Conditions to avoid:Ignition sources, contact with