CFHR5 Antibody

CFHR5 Antibody

Efficient Professional Protein and Antibody Platforms CFHR5 Antibody Basic information: Catalog No.: UMA21128 Source: Mouse Size: 50ul/100ul Clonality: Monoclonal 3A10A5 Concentration: 1mg/ml Isotype: Mouse IgG2a Purification: The antibody was purified by immunogen affinity chromatography. Useful Information: WB:1:500 - 1:2000 IHC:1:200 - 1:1000 Applications: ICC:1:200 - 1:1000 FCM:1:200 - 1:400 ELISA:1:10000 Reactivity: Human, Mouse Specificity: This antibody recognizes CFHR5 protein. Purified recombinant fragment of human CFHR5 (AA: 344-569) expressed in Immunogen: E. Coli. This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having hepa- rin binding and C reactive protein binding properties, and the C-terminal Description: repeats being similar to a complement component 3 b (C3b) binding do- main. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulo- nephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). Uniprot: Q9BXR6 BiowMW: 64.4kDa Buffer: Purified antibody in PBS with 0.05% sodium azide Storage: Store at 4°C short term and -20°C long term. Avoid freeze-thaw cycles. Note: For research use only, not for use in diagnostic procedure. Data: Gene Universal Technology Co. Ltd www.universalbiol.com Tel: 0550-3121009 E-mail: [email protected] Efficient Professional Protein and Antibody Platforms Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Figure 2:Western blot analysis using CFHR5 mAb against human CFHR5 (AA: 344-569) recombinant protein. (Expected MW is 51.8 kDa) Figure 3:Western blot analysis using CFHR5 mAb against HEK293 (1) and CFHR5 (AA: 344-569)-hIgGFc transfected HEK293 (2) cell ly- sate. Figure 4:Western blot analysis using CFHR5 mouse mAb against HepG2 (1), K562 (2), L-02 (3), SK-Hep-1 (4), SMMC-7721 (5), and NIH/3T3 (6) cell lysate. Gene Universal Technology Co. Ltd www.universalbiol.com Tel: 0550-3121009 E-mail: [email protected] .

View Full Text

Details

  • File Type
    pdf
  • Upload Time
    -
  • Content Languages
    English
  • Upload User
    Anonymous/Not logged-in
  • File Pages
    2 Page
  • File Size
    -

Download

Channel Download Status
Express Download Enable

Copyright

We respect the copyrights and intellectual property rights of all users. All uploaded documents are either original works of the uploader or authorized works of the rightful owners.

  • Not to be reproduced or distributed without explicit permission.
  • Not used for commercial purposes outside of approved use cases.
  • Not used to infringe on the rights of the original creators.
  • If you believe any content infringes your copyright, please contact us immediately.

Support

For help with questions, suggestions, or problems, please contact us