ASBMR 2011 Annual Meeting San Diego Convention Center San Diego, California, USA September 16-20, 2011 TABLE OF CONTENTS ASBMR Council/Staff .......................................................................................... v Program Committee ............................................................................................. v Abstract Reviewers ............................................................................................. vi ASBMR Committee Members/Representatives ........................................................... viii Award Winners ................................................................................................. xii Supporters ...................................................................................................... xiv General Information ........................................................................................... xv ASBMR Policies ................................................................................................ xv Continuing Medical Education Credit .................................................................... xvii Meeting Resource Materials ................................................................................. xix Travel Resources ................................................................................................ xx ASBMR Networking Center .................................................................................. xx Information for Speaker and Poster Presenters ......................................................... xxii THURSDAY, SEPTEMBER 15, 2011 ASBMR Registration Open FRIDAY, SEPTEMBER 16, 2011 Day-at-a-Glance ............................................................................................2 ASBMR Registration Open ...............................................................................4 Plenary Symposium I - Muscle and Bone Interactions ............................................... 4 Meet-the-Professor Sessions ...............................................................................4 Regulatory Opportunities and Challenges in Osteoporosis .......................................... 5 Meeting Overview for Health Professionals ............................................................ 5 Grant-Writing Workshop: Navigating the NIH Resubmission Process ........................... 6 Symposium – Osteoblast/Osteoclast Coupling ......................................................... 6 Symposium - Controversies and Concepts in Musculoskeletal Frailty ............................ 7 Symposium - Autophagy in Bone Health and Disease ............................................... 7 Symposium - Systems Approaches to Secondary Fracture Prevention: Doing Something that Actually Works ..........................................................................................8 Welcome & Announcements ..............................................................................8 Presentation of the ASBMR Louis V. Avioli Memorial Founders Award ....................... 8 Presentation of the ASBMR William F. Neuman Award ........................................... 8 ASBMR/ECTS Clinical Debate - Calcium Supplementation is Safe and Effective .............. 9 State-of-the-Art Lectures – New Concepts in Bone Remodeling ................................... 9 Oral Poster Session: Diabetes and Bone as an Endocrine Organ ................................... 9 Oral Poster Session: Vitamin D and Muscle and Bone ............................................. 10 Oral Poster Session: Vascular Calcification and Renal Bone ...................................... 11 Oral Poster Session: Osteoarthritis and Mechanotransduction .................................... 12 Posters and Exhibits Open ............................................................................... 13 Welcome Reception & Plenary Poster Session ........................................................ 13 Minority Investigator Reception ........................................................................ 39 New Investigator/New Member/First Time Attendee Reception .................................. 39 Young Investigator/Minority Investigator Networking Hour ...................................... 40 Pediatric Bone and Mineral Working Group ......................................................... 40 Working Group on Skeletal Aging ..................................................................... 40 In Vivo Working Group .................................................................................. 41 i Muscle and Bone Working Group ...................................................................... 41 SATURDAY, SEPTEMBER 17, 2011 Day-at-a-Glance ........................................................................................... 43 ASBMR Networking Breakfast ......................................................................... 45 ASBMR Registration Open .............................................................................. 45 Posters Open ............................................................................................... 45 Louis V. Avioli Memorial Lecture - Osteocytes - The Great Communicators .................. 45 Exhibits Open .............................................................................................. 45 Presentation of the ASBMR Gideon A. Rodan Excellence in Mentorship Award ............ 45 Presentation of the ASBMR Lawrence G. Raisz Award ........................................... 45 Coffee Break ................................................................................................ 45 Concurrent Oral Session 01: Osteoblasts .............................................................. 46 Concurrent Oral Session 02: Bone, Cartilage and Connective Tissue Matrix ................... 46 Concurrent Oral Session 03: Genetic Disorders of Bone ........................................... 47 Concurrent Oral Session 04: Osteoporosis Epidemiology: Biomarkers for Fracture ........... 48 Concurrent Oral Session 05: New Approaches to Osteoporosis Treatment (Preclinical) ...... 50 Concurrent Oral Session 06: John H. Carsten’s Memorial Session for Osteoporosis .......... 51 Meet-the-Professor Sessions .............................................................................. 52 Poster Session I & Poster Tours ........................................................................ 53 Special Lecture on Sarcopenia ......................................................................... 116 Meet-the-Professor Sessions ............................................................................ 116 Career Development: Building Interdisciplinary Collaboration in Research .................. 117 Clinical Roundtable/Case Conference - Anabolic Agents for Fracture Repair ................ 117 Concurrent Oral Session 07: Osteocytes ............................................................. 118 Concurrent Oral Session 08: Osteoclasts ............................................................. 119 Concurrent Oral Session 09: Calciotropic and Phosphotropic Hormones ..................... 120 Concurrent Oral Session 10: Osteoporosis Assessment: Prediction of Fracture Risk ........ 121 Concurrent Oral Session 11: Osteoporosis Treatment (Clinical): Anti-resorptive Treatment 122 Concurrent Oral Session 12: Bone Biomechanics and Quality: Animal Models .............. 123 Coffee Break .............................................................................................. 124 Clinical Update for Health Professionals ............................................................ 124 State-of-the-Art Lectures – Bone-Hematopoietic Interactions ................................... 125 Clinical Evening at ASBMR ........................................................................... 126 ASBMR Social Event - California Dreamin’ ....................................................... 126 SUNDAY, SEPTEMBER 18, 2011 Day-at-a-Glance ......................................................................................... 127 ASBMR Registration Open ............................................................................ 130 Posters Open ............................................................................................. 130 Gerald D. Aurbach Memorial Lecture - MicroRNA Control of Muscle Development and Disease ................................................................................................. 130 Exhibits Open ............................................................................................ 130 Presentation of the ASBMR Fuller Albright Award ............................................. 130 Presentation of the ASBMR Frederic C. Bartter Award ......................................... 130 Coffee Break .............................................................................................. 130 Concurrent Oral Session 13: Bone - Hematopoietic Interactions ................................ 130 Concurrent Oral Session 14: Genetic Disorders of Bone and Mineral Metabolism .......... 131 Concurrent Oral Session 15: Cancer and Bone ..................................................... 133 Concurrent Oral Session 16: Osteoporosis Epidemiology: Fracture Risk in Specific Populations ............................................................................................ 134 Concurrent Oral Session 17: Disorders of Mineral Metabolism ................................. 135 Concurrent Oral Session 18: Human Studies in Bone Biomechanics and