Product Name: CCDC70 Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated Catalog No. : TAP01-93077R-A594 Intended Use: For Research Use Only. Not for used in diagnostic procedures. Size 100ul Concentration 1ug/ul Gene ID 83446 ISO Type Rabbit IgG Clone N/A Immunogen Range Conjugation ALEXA FLUOR® 594 Subcellular Locations Applications IF(IHC-P) Cross Reactive Species Human, Mouse, Rat Source KLH conjugated synthetic peptide derived from human CCDC70 Applications with IF(IHC-P)(1:50-200) Dilutions Purification Purified by Protein A. Background Comprising nearly 4% of human DNA, chromosome 13 contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes,polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficultyeating and vulnerability to serious respiratory infections. The gene encoding CCDC70 (Coiled-coil domain-containing protein 70), a 233 amino acid secreted protein, exists on human chromosome 13. Synonyms CCDC 70; Coiled coil domain containing 70; Coiled coil domain containing protein 70; FLJ25853; CCD70_HUMAN. Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months. If unexpected results are observed which cannot be explained by variations in laboratory procedures and a problem with the reagent is suspected, contact Technical Support at [email protected] or your distributor service. .