US 20040009245A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2004/0009245 A1 Vail, III et al. (43) Pub. Date: Jan. 15, 2004 (54) METHODS AND APPARATUS TO PREVENT, 60/449,379, filed on Feb. 21, 2003. Provisional appli TREAT AND CURE INFECTIONS OF THE cation No. 60/457,085, filed on Mar. 24, 2003. Pro HUMAN RESPRATORY SYSTEM BY visional application No. 60/457,849, filed on Mar. 26, PATHOGENS CAUSING SEVERE ACUTE 2003. Provisional application No. 60/460,985, filed RESPIRATORY SYNDROME (SARS) on Apr. 7, 2003. (76) Inventors: William Banning Vail III, Bothell, WA Publication Classification (US); Marilyn L. Vail, Bothell, WA (US) (51) Int. CI.7. ... A61K 35/78 (52) U.S. Cl. .............................................................. 424/742 Correspondence Address: WILLIAM BANNING WAIL III 3123 198TH PLACE SE (57) ABSTRACT BOTHELL WA 98.012 (US) Concentrated vapors from botanical essential oils are inhaled to prevent, treat and cure infections of the respira (21) Appl. No.: 10/429,077 tory pathogens causing Severe Acute Respiratory Syndrome Filed: May 2, 2003 (“SARS”). These vapors are inhaled as a practical method to (22) reduce the risks of infection by the pathogens causing SARS Related U.S. Application Data in crowded public places. These vapors are also inhaled as a practical method to reduce the risks of infection by (63) Continuation-in-part of application No. 10/269,891, unknown, and unpredictable, respiratory pathogens that may filed on Oct. 12, 2002, which is a continuation-in-part be present in public places. The essential oils have antiseptic of application No. 10/241,441, filed on Sep. 9, 2002, properties, are Safe to inhale, and include, but are not limited which is a continuation-in-part of application No. to, the essential oils from Eucalyptus globulus, Melaleuca 09/542,703, filed on Apr. 3, 2000, now Pat. No. alternifolia, Eucalyptus citriodora, and Eucalyptus radiata. 6,447,816. Convenient hand-held inhaler apparatus are provided for the inhalation of concentrated vapors from the antiseptic essen (60) Provisional application No. 60/328,912, filed on Oct. tial oils and other Substances. The antiseptic essential oils 12, 2001. Provisional application No. 60/377,177, have Selected antiviral, antibacterial, and antifungal proper filed on May 2, 2002. Provisional application No. ties. Patent Application Publication Jan. 15, 2004 Sheet 1 of 11 US 2004/0009245 A1 F.G. 1 Patent Application Publication Jan. 15, 2004 Sheet 2 of 11 US 2004/0009245 A1 -<> `````– FIG 2 Patent Application Publication Jan. 15, 2004 Sheet 3 of 11 US 2004/0009245 A1 80 \ 86 ----- 82 84 - OD3 - FIG 3 Patent Application Publication Jan. 15, 2004 Sheet 4 of 11 US 2004/0009245 A1 FIG 4 Patent Application Publication Jan. 15, 2004 Sheet 5 of 11 US 2004/0009245 A1 100 6 CO KQ H5 NNo. FIG 5 Patent Application Publication Jan. 15, 2004 Sheet 6 of 11 US 2004/0009245 A1 112 110 104 >>>OS -------E'sNS 114 F.G. 6 Patent Application Publication Jan. 15, 2004 Sheet 7 of 11 US 2004/0009245 A1 y | <<S>S( 12 O 66 68 FIG. 7 Patent Application Publication Jan. 15, 2004 Sheet 8 of 11 US 2004/0009245 A1 124 FG 9 Patent Application Publication Jan. 15, 2004 Sheet 9 of 11 US 2004/0009245 A1 136 XNON 134 122 116 FIT-TIT 138 140 |-rrrrrr Lo CO o sx,s,szºsz,SYSSEN« CO. 142 |N 80 &ZZZZZZ NNN „ºzzZZZZZZ FIG 10 Patent Application Publication Jan. 15, 2004 Sheet 10 of 11 US 2004/0009245 A1 No. 144 116 122 FITTITT 88 80 No.S&- FIG 11 Patent Application Publication Jan. 15, 2004 Sheet 11 of 11 US 2004/0009245 A1 s COr cC)CO r- ve O) US 2004/0009245 A1 Jan. 15, 2004 METHODS AND APPARATUS TO PREVENT, and Cure Severe Acute Respiratory Syndrome (“SARS”) TREAT AND CURE INFECTIONS OF THE HUMAN Caused by the Infection of One or More Coronaviruses in RESPRATORY SYSTEM BY PATHOGENS the Human Respiratory System. An entire copy of Provi CAUSING SEVERE ACUTE RESPRATORY sional Patent Application No. 60/457,849 is incorporated SYNDROME (SARS) herein by reference. 0009 And finally, this application also relates to Provi CROSS-REFERENCES TO RELATED sional Patent Application No. 60/460,985 filed on Apr. 7, APPLICATIONS 2003 that is entitled 'Methods and Apparatus to Prevent, 0001. This application is a Continuation-in-Part Applica Treat, and Cure Severe Acute Respiratory Syndrome tion of co-pending application Ser. No. 10/269,891, having (“SARS) Caused by the Infection of Two or More Asso the Filing Date of Oct. 12, 2002, that is entitled “Methods ciated Viruses, Bacteria and Fungi'. An entire copy of and Apparatus to Prevent, Treat and Cure Infections of the Provisional Patent Application No. 60/460,985 is incorpo Human Respiratory System from Inhaled Anthrax, Small rated herein by reference. pox, Botulism, Plague, Tularemia, Hemorrhagic Fever 0010 Applicant claims priority from the above U.S. Viruses, Tuberculosis and Other Inhaled Bioterrorism Patho patent application Ser. No. 10/269,891 having the Filing gens', an entire copy of which is incorporated herein by Date of Oct. 12, 2002. Applicant also claims priority from reference. the above U.S. patent application Ser. No. 10/241,441, 0002 Ser. No. 10/269,891 is a Continuation-in-Part having the Filing Date of Sep. 9, 2002. Applicant also claims Application of co-pending application Ser. No. 10/241,441, priority from U.S. patent application Ser. No. 09/542,703 having the Filing Date of Sep. 9, 2002, that is entitled having the Filing Date of Apr. 3, 2000. “Methods and Apparatus to Prevent Colds, Flus, Tubercu 0011 Applicant also claims any priority from Provisional losis and Opportunistic Infections of the Human Respiratory Patent Application No. 60/328,912 (now expired). Applicant System of Individuals Having Cystic Fibrosis”, an entire further claims priority from Provisional Patent Application copy of which is incorporated herein by reference. No. 60/377,177. Applicant also claims priority from Provi 0003) Ser. No. 10/241,441 is a Continuation-in-Part sional Patent Application No. 60/449,379. Applicant further application of Ser. No. 09/542,703, having the Filing Date of claims priority from Provisional Patent Application No. Apr. 3, 2000 that is entitled “Methods and Apparatus to 60/457,085. Applicant also claims priority from Provisional Prevent Colds, Flus, and Infections of the Human Respira Patent Application No. 60/457,849. Applicant further claims tory System”, that issued as U.S. Pat. No. 6,447,816 on the priority from Provisional Patent Application No. 60/460, date of Sep. 10, 2002, an entire copy of which is incorpo 985. rated herein by reference. 0012. This application is related to U.S. Disclosure Docu 0004. This application relates to Provisional Patent ment No. 528,070 that has the Filing Date of Mar. 17, 2003 Application No. 60/328,912 filed on Oct. 12, 2001 that is that is entitled 'Methods and Apparatus to Prevent, Treat, entitled “Methods and Apparatus to Prevent Infections of the and Cure Infections of Severe Acute Respiratory Syndrome Human Respiratory System from Inhaled Anthrax, Small (“SARS”), an entire copy of which is incorporated herein pox, Botulism, Plague, Tularemia, Tuberculosis and Other by reference. Inhaled Bioterrorism Pathogens”. An entire copy of Provi sional Patent Application No. 60/328,912 is incorporated BACKGROUND OF THE INVENTION herein by reference. 0013. One of the inventors has poor respiratory health, 0005. This application also relates to Provisional Patent has had repeated bouts with pneumonia, colds, flu, asthma, Application No. 60/377,177 filed on May 2, 2002 that is and has been recently diagnosed with the initial Stages of entitled “Methods and Apparatus to Prevent, Treat, and Cure emphysema-despite all that modern medicine has had to Infections of the Human Respiratory System Including the offer. This first inventor also comes from a family known for Sinus Cavities, the Nasal Cavities, and the Throat'. An a long history of respiratory problems. Therefore, the inven entire copy of Provisional Patent Application No. 60/377, tors decided to look beyond conventional “modern medi 177 is incorporated herein by reference. cine' to help the first inventor, and as a result, have con ceived methods to Substantially prevent colds, flus, and 0006. This application further relates to Provisional infections of the human respiratory System. These methods Patent Application No. 60/449,379 filed on Feb. 21, 2003 include the inhalation of the vapors from eucalyptus oil that is entitled “Hand Held Inhalers”. An entire copy of and/or tea tree oil that are theorized to form a protective, and Provisional Patent Application No. 60/449,379 is incorpo infection-preventing, thin layer within the entire respiratory rated herein by reference. System, including the lungs, bronchial tubes, and the nasal cavities. This thin layer maintains its anti-pathogenic prop 0007. This application also relates to Provisional Patent erties for a period of time following the inhalation of the Application No. 60/457,085 filed on Mar. 24, 2003 that is Vapors for at least one-half hour, and perhaps longer. This entitled 'Methods and Apparatus to Prevent, Treat, and Cure thin anti-pathogenic layer Substantially prevents the initial Infections of Severe Acute Respiratory Syndrome infection of colds, flus, and other pathogens for a period of (“SARS”). An entire copy of Provisional Patent Application time following inhalation. The inventors also propose the No. 60/457,085 is incorporated herein by reference. prophylactic use of inhaled eucalyptus oil and/or tea tree oil 0008. This application further relates to Provisional to prevent additional tuberculosis, which is becoming a Patent Application No.