KIN Antibody Cat. No.: 27-540 KIN Antibody Specifications HOST SPECIES: Rabbit SPECIES REACTIVITY: Dog, Human, Rat Antibody produced in rabbits immunized with a synthetic peptide corresponding a region IMMUNOGEN: of human KIN. TESTED APPLICATIONS: ELISA, WB KIN antibody can be used for detection of KIN by ELISA at 1:312500. KIN antibody can be APPLICATIONS: used for detection of KIN by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. POSITIVE CONTROL: 1) Cat. No. 1205 - Jurkat Cell Lysate PREDICTED MOLECULAR 45 kDa WEIGHT: Properties PURIFICATION: Antibody is purified by protein A chromatography method. CLONALITY: Polyclonal CONJUGATE: Unconjugated PHYSICAL STATE: Liquid September 27, 2021 1 https://www.prosci-inc.com/kin-antibody-27-540.html Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% BUFFER: sucrose. CONCENTRATION: batch dependent For short periods of storage (days) store at 4˚C. For longer periods of storage, store KIN STORAGE CONDITIONS: antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. Additional Info OFFICIAL SYMBOL: KIN ALTERNATE NAMES: KIN, BTCD, KIN17 ACCESSION NO.: NP_036443 PROTEIN GI NO.: 13124883 GENE ID: 22944 USER NOTE: Optimal dilutions for each application to be determined by the researcher. Background and References Kin is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by the human ortholog.The protein BACKGROUND: encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by this human ortholog. REFERENCES: 1) le Acta Crystallograph. Sect. F Struct. Biol. Cryst. Commun. 62 (PT. ANTIBODIES FOR RESEARCH USE ONLY. For additional information, visit ProSci's Terms & Conditions Page. September 27, 2021 2 https://www.prosci-inc.com/kin-antibody-27-540.html.