Isopropyl Palmitate/White Soft Paraffin 2031 Light Liquid Paraffin Preparations Yellow Soft Paraffin Dünnflüssiges Paraffin; Hígan folyó paraffin; Huile de Vaseline Flu- BP 2008: Cetomacrogol Emulsifying Ointment; Cetrimide Emulsifying Keltavaseliini; Minkštasis geltonas parafinas; Paraff. Moll. Flav.; Par- Ointment; Emulsifying Ointment; Light Liquid Paraffin Eye Drops; Liquid ide; Light Liquid Petrolatum; Light Mineral Oil; Light White Min- Paraffin and Magnesium Hydroxide Oral Emulsion; Liquid Paraffin Oral affinum Molle Flavum; Petrolatum; Petroleum Jelly; Sárga vazelin; eral Oil; Paraff. Liq. Lev.; Paraffin, lättflytande; Paraffine liquide Emulsion; Simple Eye Ointment; Wool Alcohols Ointment; Vaselin, gult; Vaselina Amarela; Vaselina amarilla; Vaselina filante légère; Paraffinum Liquidum Leve; Paraffinum Liquidum Tenue; USP 31: Bland Lubricating Ophthalmic Ointment; Mineral Oil Emulsion; amarilla; Vaseline jaune; Vaselinum flavum; Vazelína žlutá; Wazeli- Mineral Oil, Rectal; Topical Light Mineral Oil. Paraffinum perliquidum; Parafiini, kevyt nestemäinen; Parafin na z˙ółta; Yellow Petrolatum; Yellow Petroleum Jelly. tekutý lehký; Skystasis lengvas parafinas; Spray Paraffin; Vaselina Proprietary Preparations (details are given in Part 3) Arg.: Babix; Lansoyl; Lax Ewe Jalea; Laxante Arceli; Laxuave Enteral; Laxuave Жёлтый Вазелин líquida. Jalea; Lexavite†; Lubritina Franklin; Modaton NI; Oilatum; Austral.: Agarol; CAS — 8009-03-8. ATC — A06AA01. Hamilton Skin Therapy; Oilatum Bar; Oilatum Emollient; Oilatum Shower ATC Vet — QA06AA01. Gel; Belg.: Lansoyl; Braz.: Nujol; Canad.: Fleet Enema Mineral Oil; Lan- Pharmacopoeias. In Chin., Eur. (see p.vii), Int., Jpn, and US. soyl; Nujol; Chile: Laxonarol; Cz.: Oilatum Emollient; Oilatum Gel; Fr.: Lan- Many pharmacopoeias use the title Vaselinum Flavum; in some In Eur. (see p.vii) and Jpn. Also in USNF. soyl; Laxamalt†; Lubentyl; Oilatum Emollient; Oilatum Soap†; Restrical; Pharmacopoeias. countries the name ‘Vaseline’ is a trade-mark. US also includes Topical Light Mineral Oil . Ger.: Agarol N†; Obstinol M; Gr.: Agarol Plain; Nujol; Paragel; Hong Ph. Eur. 6.2 (Paraffin, Yellow Soft). A purified mixture of semi- . A purified mixture of liquid Kong: Agarol; Hamilton Body Wash; Keri; Oilatum Bar; Oilatum Emollient; Ph. Eur. 6.2 (Paraffin, Light Liquid) Oilatum Gel; Vigarol; Indon.: Oilatum Bar; Oilatum Gel; Irl.: Alcoderm†; solid hydrocarbons obtained from petroleum. A yellow, translu- saturated hydrocarbons obtained from petroleum. It is a transpar- Oilatum Gel; Oilatum Junior; Oilatum Soap; Ital.: Agarol CM†; Duratirs†; cent, unctuous mass, slightly fluorescent in daylight when melt- ent, colourless, oily liquid, free from fluorescence in daylight. Malaysia: Balneum; Egozite Protective Baby Lotion; Laxaron†; Oilatum; ed. It has a drop point of 40° to 60°. Practically insoluble in wa- Relative density 0.810 to 0.875. Viscosity 25 to 80 mPa s. Prac- NZ: Fleet Mineral Enema†; Oilatum; Philipp.: Oilatum; Pol.: Oilatum; S.Afr.: Oilatum Bar; Oilatum Emollient; Singapore: Balneum; Laxarol; Nu- ter, in alcohol, and in glycerol; slightly soluble in tically insoluble in water; slightly soluble in alcohol; miscible traderm†; Oilatum Bar; Oilatum Emollient; Oilatum Gel; Spain: Emuliquen dichloromethane. Protect from light. with hydrocarbons. Protect from light. Simple; Hodernal; Switz.: Lansoyl; Laxamalt; Paragol N; Thai.: Agarol; Oil- USP 31 (Petrolatum). A purified mixture of semi-solid hydro- . A purified mixture of liquid hy- atum Bar; Oilatum Emollient; Oilatum Gel; Turk.: Duratears; Sokol; UK: USNF 26 (Light Mineral Oil) carbons obtained from petroleum. It may contain a suitable sta- drocarbons obtained from petroleum. It may contain a suitable Cetraben Emollient; Dermamist; Keri; Oilatum Bath Formula; Oilatum Fra- grance Free; Oilatum Gel; Oilatum Junior; Oilatum Soap; Zerobase; USA: biliser. It is an unctuous yellowish to light amber mass, having stabiliser. It has similar characteristics to Mineral Oil but a lower Kondremul; Liqui-Doss. not more than a slight fluorescence even after being melted. It is kinematic viscosity. Store in airtight containers. Protect from Multi-ingredient: Arg.: Agarol; Alcon Lagrimas; Aqualane; Cold Cream transparent in thin layers. It is free or practically free from odour. light. Naturel†; Mil-Par; Usar Fibras†; Austral.: Alpha Keri; DermaVeen Shower & Bath; Dermeze; Duratears; E45; Egozite Baby Cream; Granugen; Hamil- M.p. 38° to 60°. Insoluble in water; practically insoluble in cold Adverse Effects and Precautions ton Body Lotion†; Hamilton Cleansing Lotion†; Hamilton Dry Skin; Lacri- or hot alcohol and in cold dehydrated alcohol; freely soluble in Excessive oral or rectal dosage with liquid paraffin may result in Lube; Oilatum Plus; Parachoc; Pinetarsol; Rikoderm†; Soov Prickly Heat; benzene, in carbon disulfide, in chloroform, and in turpentine oil; anal seepage and irritation, excessive purgation, and watery diar- Austria: Balneum F; Neda Fruchtewurfel; Belg.: Duratears; Lacrytube; soluble in ether, in petroleum spirit, and in most fixed and vola- Tulle Vaseline†; Braz.: Agarol; Balmex; Fenogar†; Parapsyl; Canad.: Agarol rhoea. Liquid paraffin is absorbed to a slight extent and may give Plain; Akwa Tears; Alpha Keri†; Duolube; Duratears†; Episec; Huile de Bain tile oils. rise to foreign-body granulomatous reactions. Similar reactions Therapeutique; Hypotears; Lubriderm Advanced Moisture†; Lubriderm†; have followed the injection of liquid paraffin and may be consid- Magnolax; Oilatum; Optilube; Penederm†; Puralube†; Refresh Lacri-Lube; Adverse Effects erably delayed in onset. Injection may also cause vasospasm and Tears Naturale PM; Therapeutic Bath Oil†; Therapeutic Skin Lotion†; Adverse effects of soft paraffin are rare when used in topical prompt surgical removal may be required to prevent severe dam- Chile: Acnaid; Acnoxyl Jabon†; Agarol; Cold Cream Avene; Durasolets; preparations, but sensitivity reactions and acne have been report- Duratears; Lacri-Lube; Cz.: Balmandol; Balneum Hermal F; Oilatum Plus; ed after topical use. Granulomatous reactions after absorption or age. Lipoid pneumonia has been reported after aspiration of liq- Denm.: Ojensalve Neutral; Fin.: Lacri-Lube; Fr.: Cerat Inalterable; Cold uid paraffin. Because of the risk of aspiration, oral liquid paraffin Cream Naturel; Dexeryl; Lubentyl a la Magnesie; Melaxose; Oilatum Body injection and lipoid pneumonia after aspiration have occurred. should not be given to patients who have difficulty swallowing, Oil†; Oilatum Cream†; Parapsyllium; Transulose; Ger.: Allergika†; Balneum Fire risk. Burns to the scalp, face, and hands have been F; Cellosorb; Coliquifilm; Excipial; Gleitgelen; Oleobal; Parfenac Basisbad†; 1 or to those with impaired neurodevelopment. Vita-POS; Windol Basisbad†; Gr.: Duratears; Hong Kong: Alpha Keri; Bal- reported in 5 patients who accidentally ignited their hair after Some licensed product information warns that chronic ingestion neum; Duratears; Ego Skin Cream; Egozite Baby Cream; Hydromol†; Oila- the application of paraffin-based hair grease. Four patients suf- of liquid paraffin may rarely be associated with impaired absorp- tum Cream; Oilatum Plus; Polytar Emollient; Soov Prickly Heat; India: Aga- fered inhalation injury, 2 of whom required intubation. The death tion of fat-soluble vitamins and possibly other compounds. rol†; Cetraben; Cremaffin; Easylax; Indon.: Laxadine; Oilatum Plus; Yanthi of a patient who, while smoking, ignited bandages covering a Baby Oil; Irl.: Emulsiderm; Hydromol†; Lacri-Lube; Oilatum Emollient; Oil- 2 There is little published evidence to support this. Prolonged use atum Junior; Oilatum Junior Flare-Up; Oilatum Plus; Polytar Emollient†; Is- paraffin-based ointment for psoriasis, prompted the BNF to rec- should, however, be avoided. Liquid paraffin should not be used rael: Balneum F; CleanEars; Duratears; Emulsiderm; Lacrimol; Ital.: Bal- ommend that patients should be told not to smoke and to keep when abdominal pain, nausea, or vomiting is present. The UK neum Hermal Forte; Duolaxan†; Lacrilube; Malaysia: Balneum; Duratears away from flames when using paraffin-based emollients. Naturale; Ego Skin Cream; Egozite Baby Cream; Lacrilube†; Oilatum; Oila- CSM considers that it should not be used in children under 3 tum Plus Antibacterial; QV Flare Up; Soov Prickly Heat†; Mex.: Acuafil†; 1. Bascom R, et al. Inhalation injury related to use of petrolatum- years of age. Milpar; Neth.: Duratears Z; Transulose; Norw.: Simplex; NZ: Alpha Keri; based hair grease. J Burn Care Rehabil 1984; 5: 327–30. BK; DP; DP Lotion - HC; Ego Skin Cream; Egozite Baby; Hydroderm; Kari- 2. National Patient Safety Agency. Skin treatment fire risk. Patient Granuloma. References. care Breast and Body Cream†; Lacrilube; Oilatum Plus; Poly-Visc; Polytar Safety Bulletin 2007 (Jan.); 4. Available at: http:// 1. Di Benedetto G, et al. Paraffin oil injection in the body: an obso- Emollient; Philipp.: Oilatum; Oilatum Plus; Pol.: Amfobase; Balneum Her- www.npsa.nhs.uk/EasySiteWeb/GatewayLink.aspx?alId=6341 lete and destructive procedure. Ann Plast Surg 2002; 49: 391–6. mal F; Diprobase; E45; Mentho-Paraffinol; Oilatum Plus; Unibasis; Port.: (accessed 29/08/08) Banholeum Gele; Betacade†; Melaxose; Oleoban Gel†; S.Afr.: Oilatum Lipoid pneumonia. References. Plus; Singapore: Balneum; DermaVeen Shower & Bath; Duratears; Ego Hypersensitivity. The allergenicity of soft paraffin products 1. Becton DL, et al. Lipoid pneumonia in an adolescent girl second- Skin Cream; Egozite