1 Profiles. August 13 2015 CHRISTIAN H. FIBIGER LIST OF PUBLICATIONS REFEREED PUBLICATIONS (a) Journals 1. Fibiger, H.C. and S. Balagura. Tube feeding: intestinal factors in gastric loading. Psychol. Sci. 10:373-375 (1968). 2. Campbell, B.A., Lytle, L.D. and Fibiger, H.C. Ontogeny of adrenergic arousal and cholinergic inhibitory mechanisms in the rat. Science 166:637-638 (1969). 3. Klonoff, H., Fibiger, H.C. and Hutton, G. Neuropsychological patterns in chronic schizophrenia. J. Nerv. Ment. Dis. 150:291-300 (1970). 4. Campbell, B.A. and Fibiger, H.C. The effects of insulin on spontaneous activity during food deprivation. J. Comp. Physiol. Psychol. 71:341-346 (1970). 5. Fibiger, H.C. and Campbell, B.A. Effect of adrenal demedullation on starvation induced behavioral arousal. Physiol. Behav. 71:341-346 (1970). 6. Fibiger, H.C. and Campbell, B.A. The effect of para-chlorophenylalanine on spontaneous locomotor activity in the rat. Neuropharmacology 10:25-32 (1971). 7. Fibiger, H.C., Lytle, L.D. and Campbell, B.A. Cholinergic modulation of adrenergic arousal in the developing rat. J. Comp. Physiol. Psychol. 72:384-389 (1970). 8. Fibiger, H.C., Lynch, G.S. and Cooper, H.P. A biphasic action of central cholinergic stimulation on behavioral arousal in the rat. Psychopharmacologia 20:366-382 (1971). 9. Fibiger, H.C., Fox, M., McGeer, E.G. and McGeer, P.L. The effect of amantadine on spontaneous locomotor activity in the rat. J. Pharm. Pharmacol. 23:724-725 (1971). 10. McGeer, E.G., Fibiger, H.C. and Wickson, V. Differential development of caudate enzymes in the neonatal rat. Brain Res. 32:433-440 (1971). 11. Campbell, B.A. and Fibiger, H.C. Potentiation of amphetamine-induced arousal by starvation. Nature 233:424-425 (1971). 12. Fibiger, H.C., Lonsbury, B., Cooper, H.P. and Lytle, L.D. Early behavioural effects of intraventricular administration of 6-hydroxydopamine in the rat. Nature 236:209-211 (1972). 13. Fibiger, H.C., Mertz, P. and Campbell, B.A. The effect of para-chlorophenylalanine on aversion thresholds and reactivity to shock. Physiol. Behav. 8:259-263 (1972). 2 14. Fibiger, H.C., Trimbach, C. and Campbell, B.A. Enhanced stimulant properties of d- amphetamine after chronic reserpine treatment in the rat: Mediation by hypophagia and weight loss. Neuropharmacology 11:57-67 (1972). 15. Fibiger, H.C. and McGeer, E.G. Effect of acute and chronic methamphetamine treatment on tyrosine hydroxylase activity in brain and adrenal medulla. Eur. J. Pharmacol. 16:176-180 (1971). 16. McGeer, E.G., Fibiger, H.C., McGeer, P.L. and Wickson, V. Aging and brain enzymes. Exp. Geron. 6:391-396 (1971). 17. McGeer, P.L., McGeer, E.G., Fibiger, H.C. and Wickson, V. Neostriatal choline acetylase and cholinesterase following selective brain lesions. Brain Res. 35:308-314 (1971). 18. Fibiger, H.C., Pudritz, R.E., McGeer, P.L. and McGeer, E.G. Axonal transport in nigral neurons. Nature 237:177-179 (1972). 19. Fibiger, H.C., Pudritz, R.E. McGeer, P.L. and McGeer, E.G. Axonal transport in nigro- striatal and nigro-thalamic neurons: Effects of medial forebrain bundle lesions and 6- hydroxydopamine. J. Neurochem. 19:1697-1708 (1972). 20. McGeer, E.G., Fibiger, H.C. and McGeer, P.L. Brain enzymes in amantadine-treated rats. Biochemical Med. 6:189-191 (1972). 21. McGeer, E.G., Fibiger, H.C., McGeer, P.L. and Brooke, S. Temporal changes in amine synthesizing enzymes of rat extra-pyramidal structures after hemitransections or 6- hydroxydopamine administration. Brain Res. 52:289-300 (1973). 22. Fibiger, H.C., Fibiger, H.P. and Zis, A. Attenuation of amphetamine induced motor stimulation and stereotypy by 6-hydroxydopamine in the rat. Br. J. Pharmacol. 47:683-692 (1973). 23. Fibiger, H.C., Zis, A.P. and McGeer, E.G. Feeding and drinking deficits after 6- hydroxydopamine administration in the rat: Similarities to the lateral hypothalamic syndrome. Brain Res. 55:135-148 (1973). 24. Phillips, A.G. and Fibiger, H.C. Dopaminergic and noradrenergic substrates of positive reinforcement: Differential effects of d- and l-amphetamine. Science 179:575-577 (1973). 25. Hattori, T., Fibiger, H.C., McGeer, P.L. and McGeer, E.G. On the source of GABA containing terminals in the substantia nigra: Electron microscopic autoradiographic and biochemical studies. Brain Res. 54:103-114 (1973). 26. Fibiger, H.C., McGeer, E.G. and Atmadja, S. Axoplasmic transport of dopamine in nigro-striatal neurons. J. Neurochem. 21:373-385 (1973). 3 27. Corcoran, M.E., Fibiger, H.C., McGeer, E.G. and Wada, J.A. Potentiation of leptazol seizures by 6-hydroxydopamine. J. Pharm. Pharmacol. 25:497-499 (1973). 28. Phillips, A.G. and Fibiger, H.C. Substantia nigra: Self-stimulation and post-stimulation feeding. Physiological Psychol. 1:233-236 (1973). 29. Maler, L., Fibiger, H.C. and McGeer, P.L. Demonstration of the nigro-striatal projection by silver staining after nigral injections of 6-hydroxydopamine. Exp. Neurol. 40:505-515 (1973). 30. McGeer, P.L., McGeer, E.G. and Fibiger, H.C. Choline acetylase and glutamic acid decarboxylase in Huntington's chorea: A preliminary study. Neurology 23:912-917 (1973). 31. McGeer, P.L., McGeer, E.G. and Fibiger, H.C. Glutamic acid decarboxylase and choline acetylase in Huntington's chorea and Parkinson's disease. Lancet, Sept. 15, p. 623 (1973). 32. Fibiger, H.C. and McGeer, E.G. Increased axoplasmic transport of 3H-dopamine in nigro-neostriatal neurons after reserpine. Life Sci. 13:1565-1571 (1973). 33. Hattori, T., Fibiger, H.C., McGeer, P.L. and Maler, L. Analysis of the fine structure of the dopaminergic nigro-striatal projection by electron microscopic autoradiography. Exp. Neurol. 41:599-611 (1973). 34. Fibiger, H.C., Phillips, A.G. and Clouston, R.A. Regulatory deficits after unilateral electrolytic or 6-OHDA lesions of the substantia nigra. Am. J. Physiol. 225:1282-1287 (1973). 35. Phillips, A.G. and Fibiger, H.C. Deficits in stimulation-induced feeding after intraventricular administration of 6-hydroxydopamine in rats. Behav. Biol. 9:749-754 (1973). 36. Singh, V.K., Fibiger, H.C., McGeer, E.G. and McGeer, P.L. Analysis of proteins undergoing axonal transport in nigrostriatal neurons in the rat. J. Neurochem. 22:119-124 (1974). 37. Fibiger, H.C. and McGeer, E.G. Accumulation and axoplasmic transport of dopamine but not of amino acids by axons of the nigro-neostriatal projection. Brain Res. 72:366-369 (1974). 38. Fibiger, H.C., Phillips, A.G. and Zis, A.P. Deficits in instrumental responding after 6- hydroxydopamine lesions of the nigro-neostriatal dopaminergic projection. Pharmacol. Biochem. Behav. 2:87-96 (1974). 39. Singh, V.K., Fibiger, H.C. and McGeer, P.L. Effects of 6-hydroxydopamine on the nature of proteins undergoing axoplasmic transport in nigro-neostriatal neurons. J. Neurochem. 23:601-604 (1974). 4 40. Grewaal, D.S., Fibiger, H.C. and McGeer, E.G. 6-Hydroxydopamine and striatal acetylcholine levels. Brain Res. 73:372-375 (1974). 41. Zis, A.P., Fibiger, H.C. and Phillips, A.G. Reversal by L-DOPA of impaired learning due to destruction of the dopaminergic nigro-neostriatal projection. Science 185:960-962 (1974). 42. Fibiger, H.C. and Grewaal, D.S. Neurochemical evidence for denervation supersensitivity: The effect of unilateral substantia nigra lesions on apomorphine-induced increases in neostriatal acetylcholine levels. Life Sci. 15:57-63 (1974). 43. Corcoran, M.E., Fibiger, H.C., McCaughran, J.A. and Wada, J.A. Potentiation of amygdaloid kindling and metrazol-induced seizures by 6-hydroxydopamine in rats. Exp. Neurol. 45:118-133 (1974). 44. McGeer, E.G., Searl, K. and Fibiger, H.C. Chemical specificity of dopamine transport in the nigro-neostriatal projection. J. Neurochem. 24:283-288 (1975). 45. Price, M.T.C. and Fibiger, H.C. Apomorphine and amphetamine stereotypy after 6- hydroxydopamine lesions of the substantia nigra. Eur. J. Pharmacol. 29:249-252 (1974). 46. Fibiger, H.C., Zis, A.P. and Phillips, A.G. Haloperidol-induced disruption of conditioned avoidance responding: Attenuation by prior training or by anticholinergic drugs. Eur. J. Pharmacol. 30:309-314 (1975). 47. Price, M.T.C. and Fibiger, H.C. Discriminated escape learning and response to electric shock after 6-hydroxydopamine lesions of the nigro-neostriatal dopaminergic projection. Pharmacol. Biochem. Behav. 3:285-290 (1975). 48. Phillips, A.G., Brooke, S.M. and Fibiger, H.C. Effects of amphetamine isomers and neuroleptics on self-stimulation from the nucleus accumbens and dorsal noradrenergic bundle. Brain Res. 85:13-22 (1975). 49. Brooke, S.M. and Fibiger, H.C. Differential rates of increase in pontine tyrosine hydroxylase and dopamine b-hydroxylase activities after reserpine. Brain Res. 85:532-534 (1975). 50. Hattori, T. Fibiger, H.C. and McGeer, P.L. Demonstration of a pallido-nigral projection innervating dopaminergic neurons. J. comp. Neurol. 162:487-504 (1975). 51. Fibiger, H.C. and Phillips, A.G. The role of dopamine and norepinephrine in the chemistry of reward. J. Psychiat. Res. 11:135-144 (1974). 52. Roberts, D.C.S., Zis, A.P. and Fibiger, H.C. Ascending catecholamine pathways and amphetamine-induced locomotor activity: Importance of dopamine and apparent non- involvement of norepinephrine. Brain Res. 93:441-454 (1975). 5 53. Zis, A.P. and Fibiger, H.C. Neuroleptic induced deficits in food and water regulation: Similarities to the lateral hypothalamic syndrome. Psychopharmacologia 43:63-68 (1975). 54. Roberts, D.C.S., Price, M.T.C. and Fibiger, H.C. The dorsal tegmental noradrenergic projection: An analysis of its role in learning. J. Comp. Physiol. Psychol. 90:363-372 (1976). 55. Zis, A.P. and Fibiger, H.C. Functional evidence for postsynaptic supersensitivity of central noradrenergic receptors after denervation.