RHODE ISLAND M EDiCAL J ournal ZOOM – It’s a Match! Virtual National Match Day is largest on record See page 75 R SPECIAL SECTION, PART II BIOMEDICAL/TRANSLATIONAL RESEARCH in RI GUEST EDITORS: JAMES PADBURY, MD; BONGSUP CHO, PhD ApRiL 2021 VOLUME 104 • NUMBER 3 iSSN 2327-2228 REINVENTING WHAT YOU EXPECT FROM A MEDICAL PROFESSIONAL LIABILITY PROVIDER. With Coverys, you can reduce the distractions that come between diagnosis and outcomes. By leveraging claims data and analytics plus innovative educational resources, we’re helping doctors and administrators reduce distractions and focus on improving clinical, operational, and financial outcomes.Visit coverys.com Insurance products issued by ProSelect® Insurance Company (NE, NAIC 10638) and Preferred Professional Insurance Company® (NE, NAIC 36234). RHODE ISLAND M EDICAL J OURNAL 15 Translational Research: The Time is Now JAMES F. PADBURY, MD BONGSUP P. CHO, PhD GUEST EDITORS James F. Padbury, MD Bongsup Cho, PhD 17 The Time is NOW: Filling the Gaps in Treatment of Opioid-Exposed Infants: A Prospective, Pragmatic, Randomized Control Drug Trial ADAM J. CZYNSKI, DO; ABBOT R. LAPTOOK, MD 22 COBRE on Opioid and Overdose: A Collaborative Research-Based Center Addressing the Crises in Rhode Island and Beyond TRACI C. GREEN, PhD, MSc; ELIANA KAPLOWITZ, BA; KIRSTEN LANGDON, PhD; JACLYN M.W. HUGHTO, PhD, MPH; WILLIAM C. GOEDEL, PhD; ADAM J. CZYNSKI, DO; GAYLE FRASER, BS; JOSIAH RICH, MD, MPH 27 Brown University COBRE Center for Addiction and Disease Risk Exacerbation PETER M. MONTI, PhD; JENNIFER W. TIDEY, PhD; JASJIT S. AHLUWALIA, MD 32 The Center of Biomedical Research Excellence (COBRE) for Perinatal Biology – Accomplishments, Impact, and Long-term Results SUNIL K. SHAW, PhD 36 Rhode Island COBRE Center for Central Nervous System Function: Progress and Perspectives JEROME N. SANES, PhD 41 Advance-CTR: Statewide Infrastructure to Improve Health in Rhode Island through Clinical and Translational Research VALERIE ZABALA, PhD; GABRIELLE STRANIERI, BA; HEATHER FOURNIER, MA; EDWARD HAWROT, PhD; JAMES F. PADBURY, MD 3 RHODE ISLAND M EDICAL J OURNAL 8 VINTAGE COMMENTARY Searching for a Lost Cousin during the Depression and War Years Tribute to an Israeli physician STANLEY M. ARONSON, MD 10 COMMENTARY New Rules for Patient Data Sharing Risk Harm to our Most Vulnerable JESSICA J. POURIAN, MD; DANIEL COGHLIN, MD Cognitive Sinks & the Bermuda Triangle of fMRI Cognitive Studies JOSEPH H. FRIEDMAN, MD 14 LETTER TO THE EDITORS ‘Man Therapy’ website addresses suicide risk in men Program introduced in Washington County ROBERT HARRISON, Jr., MD AMA statement on CMS decision to update Medicare payments for administrating COVID-19 vaccine SUSAN R. BAILEY, MD 66 RIMS NEWS Working for You 70 RIMJ OUT OF THIS WORLD Jezero Crater, Mars 71 SPOTLIGHT ‘Smart Bandage’ detects, could prevent infections URI chemical engineering professor embeds nanosensors in microfibers to create ‘smart bandage’ 4 RHODE ISLAND M EDICAL J OURNAL IN THE NEWS VACCINATION IN RI 72 77 BUTLER HOSPITAL new State-run sites open investigational drug for AD treatment shows significant results in slowing symptoms VACCINE ELIGIBILITY 72 expands for Veterans, spouse, caregivers 77 PROVIDENCE VA heart failure with reduced ejection fraction CDC REAL-WORLD STUDY 73 treatment study funded confirms protective benefits of mRNA COVID-19 vaccines 78 RHODE ISLAND HOSPITAL memory disorders researcher launches landmark RI DEPArtmENT OF HEALTH 73 study of brain health following major surgeries updates monoclonal antibody treatment regimens 78 HASBRO HOSPITAL WORLD HEALTH ORGANIZATION (WHO) 74 PRoMPT BOLUS study measures potential calls for further studies, data on origin of SARS-CoV-2 improvement in children with sepsis virus, reiterates that all hypotheses remain open 79 URI COLLEGE OF PHARMACY VirtUAL MATCH DAY 75 among best in nation in postdoctoral at Brown residency placement rate 2021 RESIDENCY MATCH 76 79 RHODE ISLAND HEALTH CARE PROVIDERS largest on record join nationwide movement to improve older adults’ care PEOPLE/PLACES MArthA L. WOFFORD 80 81 JAMES K. SULLIVAN, MD, PhD named BCBSRI president named CMO at and CEO CNE Medical Group TRACEY M. GUTHRIE, MD 80 82 NIKOS TAPINOS, MD, PhD named Chair-Elect, American Association of earns Bruce M. Selya Award Directors of Psychiatric for Excellence in Research Residency Training 83 Ortho RHODE ISLAND celebrates opening of flagship LINDA L. CARPENTER, MD 81 campus in Warwick named President-Elect of the Society of 83 ROGER WILLIAMS MEDICAL CENTER Biological Psychiatry opens Behavioral Health and Substance Use Emergency Treatment Unit STAR HAMPTON, MD 81 named Chief Education 84 OBITUARIES Officer at CNE William D. Graham, MD Howard Sturim, MD Leonard Jason Triedman, MD Robin Wallace, MD 5 ApRiL 2021 VOLUME 104 • NUMBER 3 RHODE ISLAND Rhode Island Medical Society R I Med J (2013) M EDiCAL J ournal PUBLISHER 2327-2228 RHODE ISLAND MEDICAL SOCIETY 104 PRESIDENT CATHERINE A. CUMMINGS, MD 3 PRESIDENT-ELECT 2021 ELIZABETH B. LANGE, MD VICE PRESIDENT THOMAS A. BLEDSOE, MD April IMAGES IN MEDICINE Secretary 46 Spontaneous Pneumomediastinum in a Healthy 25-Year-Old Male KARA STAVROS, MD 1 JULIE WOODSIDE, PA-C; RICHARD V. MORGERA, MD TREASURER KWAME DAPAAH-AFRIYIE, MD, MBA 49 Pneumomediastinum in a Patient with EXECUTIVE DIRECTOR Cannabinoid Hyperemesis Syndrome NEWELL E. WARDE, PhD MARC J. VECCHIO, MD; WILLIAM D. BINDER, MD, FACEP EDITORS-IN-CHIEF WILLIAM BINDER, MD EDWARD FELLER, MD CASE Report ASSociate EDITOR 51 Chin Numbness as a Presenting Symptom of Malignancy KENNETH S. KORR, MD CHRISTIAN E. BUSTAMANTE, MD; KYLE DENISON MARTIN, DO, MPH, DTM&H; EDITOR-IN-CHIEF EMERITUS JOSEPH H. FRIEDMAN, MD EMILY COLYER, DO PUBlication Staff MANAGING EDITOR CONTRIBUTIONS MARY KORR 53 Characterizing the Symptoms of Patients with Persistent [email protected] Post-Treatment Lyme Symptoms: A Survey of Patients GRAPHIC DESIGNER at a Lyme Disease Clinic in Rhode Island MARIANNE MIGLIORI SARA E. VARGAS, PhD; MEGHAN MCCARTHY, ScB; MATTHEW BOUDREAU, BA; ADvertiSING ADMINIStrator DYLAN CANFIELD, BA; REBECCA REECE, MD; TIMOTHY FLANIGAN, MD DULCINEIA COSME [email protected] 58 How to Build It So They’ll Come: Faculty Opinion on Faculty Development JENNIFER JEREMIAH, MD; KELLY MCGARRY, MD; JOAO FILIPE MONTEIRO, PhD; DOMINICK TAMMARO, MD PUBLIC HEALTH 62 HEALTH BY NUMBERS The Association between Exercise in the Last Trimester of Pregnancy and Low Infant Birthweight among Rhode Island Mothers, 2016–2018 SCARLETT BERGAM, BA; KARINE MONTEIRO, MPH; MORGAN ORR, MPH; ANNIE GJELSVIK, PhD RHODE ISLAND MEDICAL JOURNAL (USPS 464-820), a monthly publication, is owned and published by the Rhode Island Medical Society, 405 Promenade Street, Suite 65 Vital Statistics A, Providence RI 02908, 401-331-3207. All ROSEANN GIORGIANNI, DEPUTY STATE REGISTRAR rights reserved. ISSN 2327-2228. Published articles represent opinions of the authors and do not necessarily reflect the official policy of the Rhode Island Medical Society, unless clearly specified. Advertisements do not im- ply sponsorship or endorsement by the Rhode Island Medical Society. © COPyright 2013–2021, RHODE ISLAND MEDICAL SOCIETY, ALL RIGHTS RESERVED. 6 Your patient care model has evolved. Has your risk management kept pace? Telemedicine creates new opportunities for healthcare organization, but it also comes with a whole new set of hidden risks, including increased cybersecurity, liability claims, and compliance gaps. You need a partner who can help you keep up with emerging risks. HUB can help. Our insurance and risk management specialists can keep you protected — so you can continue to focus on patient care. hubinternational.com/rimed Put our resources to work for you. Daniel Nissi, LIA 508-259-9480 [email protected] Risk & Insurance | Employee Benefits | Retirement & Private Wealth VINTAGE Commentary [Editor’s Note: The following commentary was written by the late Stanley M. Aronson, MD, founding dean of the Alpert Med- ical School of Brown University, who served as Editor-in-Chief of the Rhode Island Medical Journal for more than a decade.] Searching for a Lost Cousin during the Depression and War Years Tribute to an Israeli physician STANLEY M. ARONSON, MD 8 9 EN IF THEY ACHIEVED LITTLE to purchase postal money get to Turkey, where he was currently else, the Depression years orders, which were then living or whether his parents were yet of the 20th Century left us faithfully mailed to the alive. The family had no way of commu- with enduring memories. old country. And each nicating with him and the weeks that hor Stanley M. Aronson, MD, Found- Those early Depression month we received word followed were weeks of anguish. ing dean of the Alpert Medical years witnessed bank fail- from Europe of Cousin Months passed with no further word School of Brown University; for- mer Editor-in-Chief of the Rhode ures, families evicted from Hugo’s educational prog- from Hugo and during that interval we Island Medical Journal for more their homes for failure to ress, how well he did and learned from other sources that Hugo’s than a decade.] pay rent, soup kitchens on finally, in 1936, when he family back in Czernowitz were all major street corners and was admitted to medical victims of the Holo- In the early spring ill-clad men wandering school in the city of Cluj, caust. Hugo’s letter, the streets at midday seek- in northern Romania. by then a precious of 1946, when I was ing itinerant employment. But there family document, returning from the was also a fragile sense of hope that the September 1939: was read and reread Army, I received a recent election of President Franklin War breaks out in Europe during the months D. Roosevelt might counteract the When war arrived in Europe on the first of silence. Early call from my mother economic and emotional despondency day of September 1939, my family lost in 1947 we finally excitedly exclaiming, which gripped the nation in 1932. contact with Hugo and his family.