HSC! hps://edrolo.com.au/subjects/biology/biology/search-be"er-health/pasture- Biology! and-koch/lesson-yourturn/ Biology 9.4! [Search for Better Health]! HSC! Biology! 3. During the second half of the 19th century, ! the work of Pasteur and Koch and other scientists! stimulated the search for microbes as causes! of disease! ! Pasteur and Koch! Louis Pasteur (1822-1895)! French Chemist! - Developed the germ theory of disease" -! Developed a process called Pasteurisation " -! Disproved the theory of spontaneous generation with his ‘classic experiment’" Pasteurs classic experiment www.studyblue.com Louis Pasteur en.wikipedia.org Robert Koch (1843-1910)! German Doctor! -! Proposed Koch’s Postulates " ___________________________________" ___________________________________" -! Koch’s Postulates " 1.! The organism a thought to cause the disease _______________________________" 2.! This organism is isolated ____________________________________________" 3.! This growth is _____________________________________________________" 4.! Organisms must be re-isolated from the second host and _______________________________________________" Robert Koch www.rugusavay.com Practice Problem! The work of which of the following scientist led to the understanding of the orle of microbes in decay?" " (A)!Ronald Ross" (B)!MacFarlane Burnet" (C)!Robert Koch" (D)!Louis Pasteur " Your Turn! Eight sick animals were found to be suffering from the same symptoms. Blood tests showed they were infected with the same type of bacterium. Which of the following strategies would be best to determine if this parGcular type of bacterium is the cause of the disease? (A)! Find other animals with the same symptoms. A"empt to isolate the same type of bacterium from their blood (B)! Inject blood from animals with the symptoms into suitable host individuals. If they develop the same symptoms, this proves this type of bacterium caused the disease (C)! Use bacterium from the blood of the animals with the symptoms to infect suitable host individuals. If they develop the disease, aempt to isolate the same type of bacterium from their blood (D)! Treat all eight animals with anGbioGcs known to kill this type of bacterium. They will recover if this type of bacterium is the cause of the disease. .