A1 HRI London 2019—Cutting Edge Research in Homeopathy: Presentation Abstracts June 14–16, 2019 London Homeopathy 2020;109:A1–A28. Oral Abstracts Conclusion: These recommendations are part of a program to improve good practice in supportive care. They A001. Homeopathy and Expert Consensus are indicative and do not replace in any way an individualised Recommendations – Unlikely Bedfellows? New Research in homeopathic consultation. They are very safe to use as there Homeopathy and Expert Consensus Recommendations in are no medicine interactions and no significant side effects of Oncological Supportive Care homeopathic medicine. This is the first time that such an Jean-Lionel Bagot1,2,3, Jean-Claude Karp4, Christiane approach has been implemented in homeopathy circles. The Messerschmitt5, Véronique Lavallée6, Ingrid Theunyssen7, same methodology could be used for other pathologies. Two Jean-Philippe Wagner8 years’ hindsight has shown that they are indeed comfortable 1Dept of Integrative Medicine, Saint Anne Hospital, Strasbourg, France bedfellows. 2Robertsau Radiotherapy Center, Strasbourg, France Keywords: Expert consensus, oncological supportive 3Main General Practice Surgery, Strasbourg, France care, homeopathy 4Troyes Hospital Centre, Dept of Oncology-Radiotherapy, Troyes, France 5Pharmacy des Grisettes, Montpellier, France A002. Homeopathy and Environmental Challenges 6General Practice Surgery, Résidence Pasteur, Le Haillan, France Leoni V. Bonamin1 7Breast Unit, City-Clinic Louise, Bruxelles, Belgium 1Graduation Program on Environmental and Experimental 8Andrée Dutreix Cancer Institute, Dunkerque, France Pathology, Universidade Paulista, São Paulo, Brazil Context: Homeopathy is the integrative medicine Homeopathy is growing in areas beyond human medi- most widely used by patients with cancer in France. However, cine because of its capacity to act on all living systems. In there were as yet no supportive care guidelines for this agriculture and cattlefarms,especially those oriented to organic therapy. The International Homeopathic Society of Support- production, homeopathy has been a very useful tool and works ive Care in Oncology (www.shisso-info.com) aimed to make in harmony with the concept of sustainability, including its recommendations in order to propose to all health profes- application in biodynamic agriculture and agro-forestry. sionals concerned with supportive care, a homeopathic pre- In Brazil, more than 15 companies are established to scription tool respecting the principles of similitude, manufacture homeopathic products for animal and vegetal individualisation and of the infinitesimal dose. use. The use of homeopathy has been present in zoos and Method: We used the method of expert consensus protective organizations for wild animals, mainly in epidemic proposed by the French High Health Authority (HAS). It is a situations. This new perspective points towards a putative consensus method for writing a small number of concise, ecological role of homeopathy. unambiguous recommendations, answering the questions In a recent study, we verified the protective role of asked. This method is proposed when there is a paucity of isotherapy in Artemia salina exposed to pesticides and heavy scientific argument on the subject, which is the case here. metals, highlighting that this crustacean is a known experi- Seven steering groups studied respectively cancer mental model of eco-toxicology. The treatment of Artemia disclosure, surgery, chemotherapy, targeted therapies, radia- cysts exposed to glyphosate and lead with the respective tion therapy, hormone therapy and the post-cancer period. isotherapeutic, induced better adaptation of these animals to This document was downloaded for personal use only. Unauthorized distribution is strictly prohibited. These recommendations were presented during the plenary the harmful medium, reducing the level of egg hatching and session which brought together some fifty physicians, phar- the incidence of malformations in the newborn nauplii. macists, oncologists or surgeons specializing in homeopathic Other parameters, like motility and general activity, supportive care. also improved after the treatment. Physicochemical analyses Results: Thirty recommendations were discussed, of the water are still in progress, to provide some understand- amended and unanimously adopted or not during the plenary ing about the mechanisms involved in this protection. In session. Some side effects, such as fatigue for example, are another set of experiments performed in vitro, the corre- common to every patient, because the effects of cancer spondence between changes in the dipole moment of ho- medication are stronger than an individual’s reaction. Certain meopathic medicines and of the culture medium of situations, however, require an individualised homeopathic responsive single cells could also be observed, using solva- consultation. tochromic dyes. This suggests that electric resonance could be Copyright © 2020 The Faculty of DOI https://doi.org/ISSN 1475-4916. Homeopathy 10.1055/s-0037- 1608960 A2 Presentation Abstracts a possible mechanism involved in the homeopathic treat- Conclusion: An activating effect of the intestinal mi- ment of an aqueous medium. crobiome's resistance can be postulated for both Okou. moth- Under this hypothesis, another field study was set up, er tincture and 3x. using the same method. The treatment of a natural water Keywords: Okoubaka, microbiome, SHIME®, in vitro source with Phos 30 cH produced significant changes of the dipole moment in water samples harvested from different and distant locales of the same environment. That was similar A004. Immobilisation of Solvatochromic Dyes on to those effects observed in the medicine itself. The samples Transparent Membranes; a Simple and Effective Method for were taken before, and at different times after, water treat- Investigating the Physics of Homeopathic Potencies ment. The same signals could be measured, even in distant Steven J. Cartwright1 points of the water flow, up to 72 hours after the immersion 1Cherwell Innovation Centre, Oxford, United Kingdom of Phos 30 cH into the source. These studies show the importance of knowing how Background and Aims: Solvatochromic dyes have far the homeopathic signal can reach in nature, mainly in demonstrated themselves to be effective detectors of homeo- water, and unveils the putative role of homeopathy in recov- pathic potencies. Current research is directed at the immobi- ering environmental disturbances. lisation of solvatochromic dyes onto transparent membranes Keywords: Environmental sciences, basic research, in order to examine in detail the primary interaction between physicochemical models, high dilutions technology a range of different homeopathic medicines across potency scales. Methods: It has been found that a number of solvato- A003. In-vitro Evaluation of the Anti-pathogenic Activity of chromic dyes can be covalently immobilised onto cellulose Okoubaka aubrevillei Mother Tincture/3x in the Human membranes, thereby allowing a direct examination of the Gastrointestinal Tract Using the SHIME Technology primary interaction between homeopathic potencies and Platform molecular detectors. Immobilisation means that dye aggre- Susann Buchheim-Schmidt1, Uwe Peters2, Cindy Duysburgh3, gation cannot occur and therefore a much clearer picture is Pieter Van den Abbeele3, Massimo Marzorati3, Thomas Keller4, beginning to emerge with respect to the kinetics and ther- Petra Klement1, Stephan Baumgartner5 modynamics of potency-dye interactions. 1Deutsche-Homöopathie-Union DHU-Arzneimittel GmbH & Co. KG, Results: One surprising finding already emerging is Karlsruhe, Germany that the interaction between dyes and potencies is hysteretic 2AMT e.V., Breitscheid, Germany or S-shaped. This behaviour is characteristic of positive feed- 3Prodigest, Gent, Belgium back loops or auto-catalytic processes where a process self- 4ACOMED Statistik, Leipzig, Germany strengthens over time before eventually reaching a maxi- 5Institute of Integrative Medicine, University of Witten/Herdecke, mum. Results suggest some kind of resonant interaction Herdecke, Germany between potencies and dyes is taking place, the strength and development of which is dependent upon starting con- Background/Aim: Okoubaka aubrevillei (Okou.) is ditions and the electronic and structural features of the dye known in homeopathy for its action on the gastrointestinal used. Further findings indicate that potencies are not con- tract, e.g. in gastroenteritis and traveler’s diarrhea. Within a stant in their strength but fluctuate over time. Simulator of the Human Intestinal Microbial Ecosystem Conclusions: What the possible causes of both the (SHIME® the modulating effect of Okou. on the activity of hysteretic behaviour of potencies and the fluctuations in physiological human proximal colon microbiota and its pre- potency strength over time are, and what they mean for ventive effect against gastrointestinal infections was homeopathy in general, will be discussed, along with what evaluated. these results may be telling us about the likely identity of Methods: Upon inoculation with fecal microbiota potencies. from a healthy donor, 4 parallel proximal colon compart- Keywords: Solvatochromism, immobilisation, feed- ments of the SHIME® were treated either with Okou. mother back, hysteresis, resonance tincture or 3x in therapeutic doses, blank and ethanol control for one week. Using the “Okoubaka-adapted” microbial com- munity from SHIME®, 48 hours “challenge