th Anniversary 5 Respiratory diseases h water outbreaks food studies modelling STI vaccine care tuberculosis resistance a hiv health water-borne s preventable s zoonoses surveillancetopic ou or molecular influenza Resp fi elds vector ethods novel investigations appraoches demology diseases ABSTRACT water care vaccine BOOK ethodological health cell European Scientifi c Conference on Applied Infectious Disease Epidemiology WATERFRONT CONGRESS CENTRE 6–8 NOVEMBER 2011, STOCKHOLM www.escaide.eu EUROPEAN CENTRE FOR DISEASE PREVENTION AND CONTROL The conference is sponsored by ECDC (European Centre for Disease Prevention and Control) and jointly organised by ECDC, EPIET (European Programme for Intervention Epidemiology), EAN (EPIET Alumni Network), TEPHINET EUROPE (Training Programs in Epidemiology and Public Health Interventions NETwork) 1 TABLE OF CONTENTS SCIENTIFIC COMMITTEE 4 ABSTRACT REVIEWERS 6 PLENARY SESSION SPEAKER ABSTRACTS 9 Keynote Plenary Session: Control of infectious diseases in complex emergency situations 10 B. Parasitic infections of increasing relevance for Europe 11 C. The Hospital as an infectious disease amplifier 12 D. Enhancing health and health equality through vaccination programmes 14 PLENARY SESSION SPEAKERS 16 PARALLEL SESSION ABSTRACTS 21 01. Antimicrobial resistance/Health Care Associated Infection 22 02. Contribution of modeling to applied epidemiology 24 03. Food- and water-borne diseases 27 04. Outbreaks 1 29 05. Vector Borne Disease 31 06. HIV – STI 33 07. Travel and mass gathering 36 08. Influenza 38 09. International Health 40 10. Migration and population movement 43 11. Vaccine uptake/coverage 45 12. Novel methodology in outbreak investigation, risk assessment and communication 48 13. From outbreak investigation to policy changes 50 14. Outbreak 2 53 15. Vaccine effectiveness 55 16. Zoonoses 57 17. Surveillance 59 18. Vaccine Safety and assessment 62 19. Vaccine Preventable Diseases 64 20. Burden of Disease 67 21. Food and Water Borne Disease: Surveillance and Methods 69 POSTER SESSION ABSTRACTS 73 Antimicrobial resistance 74 Approaches in outbreak investigation, analysis, communication and coordination 79 Contribution of modelling to applied epidemiology 85 Food- and water-borne diseases 89 Health care associated infections 95 HIV – STI 101 Influenza 106 International health 112 Migration, mass gatherings and Travel-associated infection 118 Molecular epidemiology, diagnostics and laboratory methods 121 Outbreaks 127 Surveillance 132 Tuberculosis and Respiratory Diseases 138 Vaccination: uptake, coverage and effectiveness 143 Vaccine preventable diseases 148 Vector borne diseases 154 Zoonoses 159 SPECIAL PLENARY SESSION: EHEC/HUS 2011 167 INDEX 171 by presenter 172 by subjet 176 EXTERNAL EVALUATION 184 European Scientifi c Conference on Applied Infectious Disease Epidemiology 6–8 NOVEMBEr 2011, STOCKHOLM 2 3 FOREWORD I would like to warmly welcome all delegates to the 5th ESCAIDE conference in Stockholm, the home of ECDC. We have again received a record number of abstracts to the conference this year. Hence the peer review process to select abstracts continues to increase in its rigour, which ultimately means that the scientific discussions, presentations and posters at the 2011 ESCAIDE are of increasingly high quality. I would like to offer sincere thanks to all authors who submitted an abstract to the conference and to all the colleagues who kindly assisted in carrying out over 1000 peer reviews to assess the submitted work. Finally, I offer congratulations to those authors that have been chosen to present at ESCAIDE 2011; myself and my colleagues in the Scientific Committee are greatly looking forward to learning more of the methodology and application of epidemiology, microbiology and other related disciplines that you will present during the conference in support of communicable disease prevention and control. Johan Giesecke As with every ESCAIDE, we aim to prove a forum for information exchange and knowledge sharing, and hope that you will use the opportunity to discuss the current challenges you face in your daily work. ESCAIDE is also an opportunity to meet with old friends and colleagues. This is enjoyable, but also hugely valuable – in a global environment, the possibility to rely on European and Global networks of trusted colleagues in the event of a disease outbreak or emerging infection can make a significant difference to containment and control. Hence please renew acquaintances, and also take the opportunity to meet new colleagues – it is both personally rewarding and potentially of huge professional value to do so. Another clear aim of ESCAIDE is to provide a platform for future public health experts from within the FETP (Field epidemiology training programme) and EPIET (European Programme for Intervention Epidemiology Training) programmes and EUPHEM (European Public Health Microbiology Training Programme) to present their work. We welcome all the fellows to the conference, and anticipate interesting presentations and discussions of your work. The conference this year is being held at the newly open Waterfront conference centre in Stockholm; in keeping with the name of the venue, I hope that ESCAIDE will refresh your curiosity, quench your thirst for new knowledge, and ultimately leave you awash with new ideas and enthusiasm. I wish you all an enjoyable, successful and stimulating conference. Johan Giesecke Chair, ESCAIDE Scientific Committee European Scientifi c Conference on Applied Infectious Disease Epidemiology 6–8 NOVEMBEr 2011, STOCKHOLM 4 SCIENTIFIC COMMITTEE Johan Giesecke – ECDC, Chair of ESCAIDE Pierluigi Lopalco – ECDC Scientific Committee Pierluigi is a Medical doctor, and special- Professor Johan Giesecke is Chief Scien- ist in Hygiene and Preventive Medicine. tist at the ECDC since 2005 and heads the Since 2005 Pierluigi has been working at disease programmes of the Centre in the the ECDC, where he heads the Centre’s Office of the Chief Scientist. From a back- Programme on Vaccine Preventable Dis- ground as infectious disease clinician, eases. His primary field of interest is the his research interests include: epidemic modeling, HIV/STIs epidemiological evaluation of vaccines and vaccination pro- and late sequelae of acute infections. He has published some grammes. He is co-author of about 100 papers and co-author 150 scientific papers, has written a textbook on infectious or contributor of several text books on the topic. disease epidemiology and co-edited another. Brigitte Helynck – Training Programs in Arnold Bosman – ECDC Epidemiology and Public Health Interven- tions Network (TEPHINET) representative Arnold is a Public Health Specialist, trained in the Netherlands, focused on Brigitte is a Medical Doctor, and worked providing specialised training in Inter- for 12 years in Africa (with NGOs and for vention Epidemiology to public health the French Ministry of Cooperation). She professionals. He is a member of the joined the French Public Health Service in EPIET Scientific Conference committee. 1996, and since 2000 has been working at the French Institute Currently he is a manager of Public Health Training at ECDC for Public Health Surveillance (InVS). Brigitte started the French aiming to establish an effective network of training in ap- Field Epidemiology Training Programme in 2002, and worked plied public health (e.g. epidemiology, public health micro- as an EPIET scientific coordinator in 2007–2010. Brigitte is cur- biology) in order to strengthen disease prevention & control rently in charge of training in the Scientific Department. capacity in EU. Lorenzo Pezzoli – President of the EPIET Aftab Jasir – ECDC/EUPHEM Alumni Network (EAN) Aftab is an associate professor, expert Lorenzo holds a Degree in Veterinary microbiologist and chief scientific coor- Medicine and a PhD from the University dinator of European Public Health Micro- of Turin. Between 2006 and 2008, as an biology training program (EUPHEM) at EPIET Fellow (Cohort 12), he was based at ECDC. Aftab has worked in many public the Health Protection Agency Centre for health bodies/organisations (Lund Uni- Infections in London. He currently works as an epidemiology versity hospital, Sweden; Health Protection Agency, UK; Ger- consultant for different international organizations in the area man Streptococcal Reference Laboratory, Aachen; and CDC, of monitoring and evaluation of vaccination activities mainly US). Specialisations include monitoring and evaluating QA/ in low- and middle-income countries. Since 2009 Lorenzo has QC systems, molecular typing and subtyping, and developing been the President of the EPIET Alumni Network (EAN), one molecular methods for characterisation of bacteria. Aftab is of institutions co-organizing ESCAIDE and the EPIET Seminar a member of many scientific societies and international advi- before that. sory boards. 5 Andrea Ammon – eCDC Mária Avdičová – ECDC Advisory Forum representative Andrea Ammon, MD, MPH is the Deputy to the Director and Head of Resource Man- Maria is a senior epidemiologist and the agement and Coordination Unit at the Head of Epidemiology Department in the ECDC. Prior to joining the ECDC, Dr Am- Regional Public Health Authority Banska mon served in several roles at the Robert Bystrica, Slovakia. Her department and Koch-Institute, in Berlin, Germany, most her team are responsible for the Surveil- recently as Head of Department for Infectious Disease Epide- lance and monitoring of communicable diseases in the Slovak miology. She has published over