Rabbit anti-human JPH2 (ab2) Polyclonal antibody (DPAB-L20625) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Antigen Description Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family. Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described. [provided by RefSeq, Jul 2008] Immunogen a 17 amino acid peptide near the carboxy-terminus of human JPH2. Isotype IgG Source/Host Rabbit Species Reactivity Human Conjugate Unconjugated Applications indirect ELISA: suitable Format Buffered aqueous solution Size 100μg Buffer Solution in phosphate buffered saline containing 0.02% sodium azide Preservative 0.02% Sodium Azide Storage Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C GENE INFORMATION Gene Name JPH2 junctophilin 2 [ Homo sapiens (human) ] Official Symbol JPH2 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Synonyms JPH2; junctophilin 2; JP2; JP-2; CMH17; junctophilin-2; junctophilin type 2 Entrez Gene ID 57158 Protein Refseq NP_065166 UniProt ID Q86VZ3 Function calcium-release channel activity; phosphatidic acid binding; phosphatidylinositol-3,4,5- trisphosphate binding; phosphatidylinositol-3,5-bisphosphate binding; phosphatidylinositol-3- phosphate binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylinositol-4- phosphate binding; phosphatidylinositol-5-phosphate binding; phosphatidylserine binding; protein binding 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved.