Supplemental Table 1. dCHIP Analysis of Gene Expression Changes in Ad-FHIT- transduced H1299 cells compared to those in Ad-EV-transduced cells. Probe set Gene Accession Fold Change 212352_s_at transmembrane trafficking protein BE780075 -2.801 203939_at 5' nucleotidase (CD73) NM_002526 -2.562 201812_s_at 6.2 kd protein NM_019059 -2.118 208736_at actin related protein 2/3 complex, subunit 3 (21 kD) AF004561 -2.352 213214_x_at actin, gamma 1 AW190090 -2.392 212363_x_at actin, gamma 1 AU145192 -2.373 221607_x_at actin, gamma 1 BC001920 -2.344 211983_x_at actin, gamma 1 BE741683 -2.266 201550_x_at actin, gamma 1 NM_001614 -2.173 211620_x_at acute myeloid leukemia associated protein (AML1EAP) L21756 -2.161 213892_s_at adenine phosphoribosyltransferase AA927724 -2.201 200011_s_at ADP-ribosylation factor 3 NM_001659 -2.164 211935_at ADP-ribosylation factor-like 6 interacting protein D31885 -2.173 211986_at AHNAK nucleoprotein (desmoyokin) BG287862 -2.363 202740_at aminoacylase 1 NM_000666 -2.108 208704_x_at amyloid beta (A4) precursor-like protein 2 BC000373 -2.544 208248_x_at amyloid beta (A4) precursor-like protein 2 NM_001642 -2.328 208703_s_at amyloid beta (A4) precursor-like protein 2 BG427393 -2.206 210027_s_at APEX nuclease (multifunctional DNA repair enzyme) M80261 -2.327 209135_at aspartate beta-hydroxylase AF289489 -2.263 207335_x_at ATP synthase, H+ transporting, mitochondrial F0 compl NM_007100 -2.385 217801_at ATP synthase, H+ transporting, mitochondrial F1 compl NM_006886 -2.112 200818_at ATP synthase, H+ transporting, mitochondrial F1 compl NM_001697 -2.128 216383_at ATP-binding cassette, sub-family D (ALD), member 1 U52111 -3.114 200921_s_at B-cell translocation gene 1, anti-proliferative NM_001731 -2.229 201848_s_at BCL2/adenovirus E1B 19kD interacting protein 3 U15174 -2.761 201849_at BCL2/adenovirus E1B 19kD interacting protein 3 NM_004052 -2.632 201828_x_at CAAX box 1 NM_003928 -2.235 214665_s_at calcium binding protein P22 AK000095 -2.317 200653_s_at calmodulin 1 (phosphorylase kinase, delta) M27319 -2.255 216194_s_at calpain, small subunit 1 AD001527 -2.156 215733_x_at cancer/testis antigen 2 AJ012833 -2.367 202122_s_at cargo selection protein (mannose 6 phosphate receptor NM_005817 -2.654 210844_x_at catenin (cadherin-associated protein), alpha 1 (102kD) D14705 -2.148 212097_at caveolin 1, caveolae protein, 22kD AU147399 -3.322 204490_s_at CD44 antigen (homing function and Indian blood group M24915 -2.481 212014_x_at CD44 antigen (homing function and Indian blood group AI493245 -2.251 209835_x_at CD44 antigen (homing function and Indian blood group BC004372 -2.230 211974_x_at CD59 antigen p18-20 AL513759 -2.552 201005_at CD9 antigen (p24) NM_001769 -2.329 220864_s_at cell death-regulatory protein GRIM19 NM_015965 -2.163 217122_s_at cell division cycle 2-like 2 AL031282 -2.927 209143_s_at chloride channel, nucleotide-sensitive, 1A AF005422 -2.219 208659_at chloride intracellular channel 1 AF034607 -2.143 201560_at chloride intracellular channel 4 NM_013943 -2.407 208294_x_at chorionic somatomammotropin hormone-like 1 NM_022578 -2.227 204050_s_at clathrin, light polypeptide (Lca) NM_001833 -2.212 201358_s_at coatomer protein complex, subunit beta NM_016451 -2.311 200810_s_at cold inducible RNA binding protein NM_001280 -2.279 200811_at cold inducible RNA binding protein NM_001280 -2.254 216570_x_at Consensus includes gb:AL096829 /DEF=Human DNA sAL096829 -2.459 221483_s_at cyclic AMP phosphoprotein, 19 kD AF084555 -2.348 202705_at cyclin B2 NM_004701 -2.137 208796_s_at cyclin G1 BC000196 -2.694 217491_x_at cytochrome c oxidase subunit VIIc pseudogene 1 AF042165 -2.180 200794_x_at DAZ associated protein 2 NM_014764 -2.720 210137_s_at dCMP deaminase BC001286 -2.432 202231_at dendritic cell protein NM_006360 -2.234 214247_s_at dickkopf homolog 3 (Xenopus laevis) AU148057 -2.171 201412_at DKFZP564C1940 protein NM_014045 -2.437 209177_at DKFZP564J0123 protein BC002873 -2.124 208891_at dual specificity phosphatase 6 BC003143 -2.595 211684_s_at dynein, cytoplasmic, intermediate polypeptide 2 AF250307 -2.115 205596_s_at E3 ubiquitin ligase SMURF2 AY014180 -2.430 217719_at eIEF associated protein HSPC021 NM_016091 -2.475 209058_at endothelial differentiation-related factor 1 AB002282 -2.302 37796_at erythropoietin AF053356 2.718 215096_s_at esterase Dformylglutathione hydrolase AU145746 -2.367 211234_x_at estrogen receptor 1 AF258449 -4.496 204540_at eukaryotic translation elongation factor 1 alpha 2 NM_001958 -2.098 200094_s_at eukaryotic translation elongation factor 2 AI004246 -2.588 204102_s_at eukaryotic translation elongation factor 2 NM_001961 -2.219 208726_s_at eukaryotic translation initiation factor 2, subunit 2 (beta, BC000461 -2.159 200023_s_at eukaryotic translation initiation factor 3, subunit 5 (epsiloNM_003754 -2.305 208697_s_at eukaryotic translation initiation factor 3, subunit 6 (48kD BC000734 -2.315 200912_s_at eukaryotic translation initiation factor 4A, isoform 2 NM_001967 -2.358 203719_at excision repair cross-complementing rodent repair defic NM_001983 -2.252 203720_s_at excision repair cross-complementing rodent repair defic NM_001983 -2.136 208775_at exportin 1 (CRM1 homolog, yeast) D89729 -2.373 208647_at farnesyl-diphosphate farnesyltransferase 1 AA872727 -2.553 212320_at FK506 binding protein 1A (12kD) BC001002 -2.690 206492_at fragile histidine triad gene NM_002012 6.959 201637_s_at fragile X mental retardation, autosomal homolog 1 NM_005087 -2.460 208235_x_at G antigen 7 NM_021123 -2.141 218205_s_at G protein-coupled receptor kinase 7 NM_017572 -3.223 210891_s_at general transcription factor II, i AF035737 -2.416 217814_at GK001 protein NM_020198 -2.567 217807_s_at glioma tumor suppressor candidate region gene 2 NM_015710 -3.150 209398_at H1 histone family, member 2 BC002649 -2.224 215071_s_at H1 histone family, member 4 AL353759 -2.335 200080_s_at H3 histone, family 3A AI955655 -2.133 201841_s_at heat shock 27kD protein 1 NM_001540 -2.385 208687_x_at heat shock 70kD protein 8 AF352832 -2.823 221891_x_at heat shock 70kD protein 8 AA704004 -2.739 210338_s_at heat shock 70kD protein 8 AB034951 -2.276 200064_at heat shock 90kD protein 1, beta AF275719 -2.277 201132_at heterogeneous nuclear ribonucleoprotein H2 (H') NM_019597 -2.413 202887_s_at HIF-1 responsive RTP801 NM_019058 -2.440 208025_s_at high-mobility group (nonhistone chromosomal) protein isNM_003483 -2.995 206074_s_at high-mobility group (nonhistone chromosomal) protein isNM_002131 -2.078 212552_at hippocalcin-like 1 BE617588 -2.194 218092_s_at HIV-1 Rev binding protein NM_004504 -3.984 208788_at homolog of yeast long chain polyunsaturated fatty acid eAL136939 -2.360 217917_s_at HSPC162 protein NM_014183 -2.087 211598_x_at Human PACAP type-3VIP type-2 receptor mRNA U18810 -2.104 212994_at hypothetical protein LOC57187 BE543527 3.970 220134_x_at hypothetical protein FLJ10647 NM_018166 -2.301 219126_at hypothetical protein FLJ10975 NM_018288 3.282 220774_at hypothetical protein FLJ20071 NM_017653 -2.288 220600_at hypothetical protein FLJ20211 NM_017713 2.925 212297_at hypothetical protein FLJ20986 BF218804 -2.576 202371_at hypothetical protein FLJ21174 NM_024863 -2.209 221844_x_at hypothetical protein FLJ22059 AV756161 -2.231 209679_s_at hypothetical protein from clone 643 BC003379 -2.353 218097_s_at hypothetical protein MGC2491 NM_024040 -2.270 210933_s_at hypothetical protein MGC4655 BC004908 -2.399 216271_x_at ilvB (bacterial acetolactate synthase)-like AC004794 5.654 201631_s_at immediate early response 3 NM_003897 -2.368 202105_at immunoglobulin (CD79A) binding protein 1 NM_001551 -2.371 201474_s_at integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLANM_002204 -2.488 201656_at integrin, alpha 6 NM_000210 -2.160 200791_s_at IQ motif containing GTPase activating protein 1 NM_003870 -2.284 212074_at KIAA0810 protein BE972774 -2.392 202304_at KIAA0970 protein NM_014923 -2.374 201105_at lectin, galactoside-binding, soluble, 1 (galectin 1) NM_002305 -2.491 208771_s_at leukotriene A4 hydrolase J02959 -2.419 202822_at LIM domain-containing preferred translocation partner inBF221852 -2.229 214110_s_at lymphocyte-specific protein 1 BF195104 -2.330 217871_s_at macrophage migration inhibitory factor (glycosylation-inhNM_002415 -2.119 209329_x_at mannan-binding lectin serine protease 1 (C4/C2 activati BC000587 -2.454 214254_at melanoma antigen, family A, 4 AW438674 -2.469 209014_at melanoma antigen, family D, 1 AF217963 -2.293 212859_x_at metallothionein 1E (functional) BF217861 -2.163 204745_x_at metallothionein 1G NM_005950 -2.180 211456_x_at metallothionein 1H AF333388 -2.839 206461_x_at metallothionein 1H NM_005951 -2.189 204326_x_at metallothionein 1L NM_002450 -2.235 208581_x_at metallothionein 1X NM_005952 -2.158 212185_x_at metallothionein 2A NM_005953 -2.218 212085_at mitochondrial carrier; adenine nucleotide translocator, mAA916851 -2.313 220526_s_at mitochondrial ribosomal protein L20 NM_017971 -2.528 218270_at mitochondrial ribosomal protein L24 NM_024540 -2.201 217408_at mitochondrial ribosomal protein S18B AL050361 -2.246 217942_at mitochondrial ribosomal protein S35 NM_021821 -2.188 200797_s_at myeloid cell leukemia sequence 1 (BCL2-related) AI275690 -3.358 205144_at myosin, light polypeptide 5, regulatory L03785 8.685 202298_at NADH dehydrogenase (ubiquinone) 1 alpha subcomplexNM_004541 -2.152 218160_at NADH dehydrogenase (ubiquinone) 1 alpha subcomplexNM_014222 -2.296 203478_at NADH dehydrogenase (ubiquinone) 1, subcomplex unknNM_002494 -2.190 209303_at NADH dehydrogenase (ubiquinone) Fe-S protein 4 (18kBC005270 -2.193