USO09597335B2 (12) United States Patent (10) Patent No.: US 9,597,335 B2 Tuiten et al. (45) Date of Patent: *Mar. 21, 2017 (54) USE OF TESTOSTERONE AND A 5-HT1A 5,015,646 A 5/1991 Simms AGONST IN THE TREATMENT OF SEXUAL 5,250,534 A 10, 1993 Bell et al. 5,389,687 A 2f1995 Schaus et al. DYSFUNCTION 5,565,466 A 10, 1996 Gioco et al. 5,731,339 A 3/1998 Lowrey (71) Applicant: EMOTIONAL BRAIN B.V., Almere 5,877,216 A 3, 1999 Place et al. (NL) 6,165.975 A 12/2000 Adams et al. 6,242,436 B1 6/2001 Llewellyn 6,246,436 B1 6/2001 Lin et al. (72) Inventors: Jan Johan Adriaan Tuiten, Almere 6,251,436 B1 6/2001 Drizen et al. (NL); Johannes Martinus Maria 6,294.550 B1 9, 2001 Place et al. Bloemers, Almere (NL); Robertus 6,306,841 B1 10/2001 Place et al. Petrus Johannes De Lange, Hilversum 6,423,683 B1 7/2002 Heaton et al. (NL) 6,428,769 B1 8/2002 Rubsamen et al. 6,469,012 B1 10/2002 Ellis et al. 6,469,016 B1 10/2002 Place et al. 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