Hindi Vidya Prachar Samiti’s Ramniranjan Jhunjhunwala College of Arts, Science & Commerce Hindi Vidya Prachar Samiti’s Ramniranjan Jhunjhunwala College of Arts, Science and Commerce (Autonomous) Affiliated to University of Mumbai Syllabus for T.Y.B.Sc. Semester V & VI Program: B.Sc. Course: Zoology (WEF 2019-20) 1 Hindi Vidya Prachar Samiti’s Ramniranjan Jhunjhunwala College of Arts, Science & Commerce T.Y.B.Sc. Zoology Syllabus Semester V Course code Paper and Title Unit Topic Credits Paper I: I Type study-Sepia Animal type Study, II Comparative anatomy of vertebrates–I Comparative 2.5 Skin, Digestive system and circulatory RJSUZOO501 anatomy, system Developmental III Developmental biology of frog biology & Endocrinology IV Endocrine glands and their regulation Paper II: I Basic Haematology Haematology, II Basic immunology RJSUZOO502 Immunology & III Applied haematology & immunology 2.5 Physiology IV Homeostasis- Feedback mechanism, thermoregulation &ionic regulation RJSUZOOP501 Practicals based on Paper I & II 3 &RJSUZOOP5 02 Paper III: I Molecular biology Molecular biology, II Genetic engineering RJSUZOO503 Genetic engineering, 2.5 Toxicology and III Toxicology Biostatistics IV Biostatistics Paper IV: I Human osteology Osteology, Ethology, Epidemiology, II Behavioural ethology 2.5 RJSUZOO504 Wildlife III Epidemiology-I conservation. IV National parks and sanctuaries RJSUZOOP503 Practicals based on Paper III & IV 3 &RJSUZOOP5 04 2 Hindi Vidya Prachar Samiti’s Ramniranjan Jhunjhunwala College of Arts, Science & Commerce Semester VI Course code Paper and Title Unit Topic Credits Paper I: I Type study-Shark Animal type Study, II Comparative anatomy of vertebrates II- Comparative respiratory system,urinogenital system RJSUZOO601 anatomy, and nervous system 2.5 Developmental III Developmental biology of chick biology & Histology IV Mammalian Histology Paper II: I Enzymology Enzymology, II Chemical messengers and Cardiac RJSUZOO602 Physiology and physiology 2.5 Pathology III Aspects of human reproduction IV General pathology RJSUZOOP601 Practicals based on Paper I & II 3 &RJSUZOOP602 Paper III: I Cancer biology Cancer biology, II Animal tissue culture RJSUZOO603 Biotechnology, 2.5 III Human genetics Genetics, and Bioinformatics IV Bioinformatics Paper IV I Zoogeography Environmental II Bioprospecting and Zoopharmacognosy Biology, 2.5 RJSUZOO604 Zoopharmacognosy III Epidemiology-II , Epidemiology & Wildlife IV Wildlife management management RJSUZOOP603 Practicals based on Paper III & IV 3 &RJSUZOOP604 3 Hindi Vidya Prachar Samiti’s Ramniranjan Jhunjhunwala College of Arts, Science & Commerce T. Y. B. Sc. ZOOLOGY: SEMESTER V (THEORY) Paper I- Animal type Study, Comparative anatomy, Developmental biology & Endocrinology Course Code: RJSUZOO501 Total Credits- 2.5 Course Objectives: 1. To acquaint learners with the details of Sepia as a representative of invertebrates. 2. To provide them with general idea of comparative anatomy of vertebrates. 3. To introduce concept of endocrine glands and associated disorders to the learners. Expected Outcomes: 1. Learner will get an idea of general characters and system details of Sepia. 2. Learner will be familiarized with process of evolution trend which has occurred during vertebrate evolution. 3. The learner will understand concept of hormones and its functions. Unit I: Type study: Sepia aculeata (15 lectures) 1.1: General characters External characters. Locomotion. Economic importance. 1.2: Organ systems: 1.2.1 Digestive system. 1.2.2 Respiratory system. 1.2.3 Circulatory system. 1.2.4 Excretory system. 1.2.5 Nervous system and Sense organs. 1.2.6 Reproductive system. Unit II: Comparative anatomy of vertebrates I (15 Lectures) 2.1: Skin: Functions, anatomy of vertebrate skin, epidermal and dermal derivatives, scales, claws, nails, hoofs, horns, antlers, beaks, feathers, hair and glands. 2.2: Digestive system: Digestive tube and its evolution. Tooth structure & position, teeth in lower vertebrates, mammalian dentition. 2.3: Circulatory System: Aortic arches and venous system in vertebrates. 4 Hindi Vidya Prachar Samiti’s Ramniranjan Jhunjhunwala College of Arts, Science & Commerce Unit III: Developmental biology of frog (15 lectures) Egg, spawn, cleavage, blastula, gastrula, neurula , morphogenesis and metamorphosis. Unit IV: Endocrine glands and their regulation/ Endocrinology (15 lectures) 4.1: Mammalian Endocrinology Mammalian Endocrinology: Hormones, functions of hormones and hormonal disorders of the following endocrine glands: pituitary, adrenal, thyroid, parathyroid & pancreas. 5 Hindi Vidya Prachar Samiti’s Ramniranjan Jhunjhunwala College of Arts, Science & Commerce Paper II- Haematology, Immunology & Physiology Course Code: RJSUZOO502 Total credits: 2.5 Course Objectives: 1. To introduce the different aspects of human blood and its clinical significance. 2. To introduce the topic of immunology with emphasis on building strong foundation about the immune system. 3. To acquaint learners with knowledge of diagnostic techniques in haematology as well as immunology. 4. To comprehend the physiological aspects of homeostasis and endocrinology. Expected Outcomes: 1. Learner will be able to identify various components of blood and their importance. 2. Learner will be familiarized with types of immunity and the significant role of immune system. 3. Learner will be better equipped for further pathological courses or working in a diagnostic laboratory. 4. Learner will be familiarized with adaptations of animals for regulation of heat and ionic balance. Unit I: Basic Haematology (15 lectures) 1.1: Composition of plasma: Water, respiratory gases, plasma proteins and other inorganic constituents 1.2: Haematopoiesis: Erythropoiesis, leucopoiesis and Thrombopoiesis 1.3: Erythrocytes: Structure and functions, abnormalities in structure, total count, variation in number; ESR; types of anaemia 1.4: Haemoglobin: Structure, formation and degradation; variants of haemoglobin (foetal, adult). 1.5: Leucocytes: Types and functions, total count and variation in number; leukaemia and its types. 1.6: Thrombocytes: Structure, factors and mechanism of clotting, failure of clotting mechanism. 1.7: Blood volume: Total quantity and regulation; haemorrhage. Unit II: Basic Immunology (15 lectures) 2.1: Overview of Immunology 2.1.1: Concept of immunity 2.1.2: Innate immunity - Definition, factors affecting innate immunity, Mechanisms of innate immunity - First line of defence - physical and chemical barriers; Second line of defence - phagocytosis, inflammatory responses and fever 2.1.3: Adaptive or Acquired immunity, Antibody mediated and cell mediated immunity; Active Acquired immunity - Natural and Artificial; Passive Acquired immunity - Natural and Artificial 6 Hindi Vidya Prachar Samiti’s Ramniranjan Jhunjhunwala College of Arts, Science & Commerce 2.2: Cells and Organs of immune system 2.2.1: Cells of immune system - B cells, T cells and null cells, macrophages, dendritic cells and mast cells 2.2.2: Organs of immune system Primary: Thymus and bone marrow Secondary: Lymph nodes and spleen 2.3: Antigens: Definition and properties; haptens 2.4: Antibodies: Definition, basic structure, classes of antibodies - IgG, IgA, IgM, IgD and IgE 2.5: Antigen processing and presentation 2.5.1: Endogenous antigens - cytosolic pathways. 2.5.2: Exogenous antigens - endocytic pathways. Unit III: Applied Haematology & immunology (15 lectures) 3.1: Applied Haematology: Introduction and scope. 3.2: Clinical significance of Diagnostic Techniques 3.2.1 Haemoglobinopathies (sickle cell anaemia, thalassemia) 3.2.2 Coagulopathies: Haemophilia and purpura 3.3: Biochemical examination of blood: 3.3.1 Liver function tests: Total and direct bilirubin 3.3.2. Kidney function test: Serum creatinine. 3.3.3. Carbohydrate metabolism tests: Blood sugar. 3.3.4 Other biochemical tests: Blood hormones – TSH. 3.4.: Antigen-Antibody interactions and vaccines. 3.4.1 : General features of antigen-antibody interaction 3.4.2 : Precipitation reaction - Definition, characteristics and mechanism. Precipitation in gels (slide test) - Radial immunodiffusion (Mancini method) Double immunodiffusion (Ouchterlony method) 3.4.3: Agglutination reaction definition, characteristics and mechanism. Coomb’s test 3.4.4: Immunoassay - ELISA 3.4.5: Principles of vaccines - active and passive immunization, Routes of vaccine administration. Unit IV: Homeostasis- Feedback mechanism, thermoregulation and ionic regulation (15 lectures) 4.1 Homeostasis: External and internal environment; Control systems in Biology: Feedback mechanism; control of blood glucose level as an example. 4.2 Thermoregulation: Temperature balance; Heat production; Shivering and non-shivering thermogenesis, brown fat- special thermogenic tissues in mammals and heat loss; Acclimation and acclimatization; Adaptive response to temperature: Daily torpor, Hibernation, Aestivation. 4.3 Osmotic and Ionic regulation: Maintaining water and electrolyte balance: ionic regulation in iso-osmotic, hypo-osmotic and hyper-osmotic environment, Problems of living in terrestrial environment: water absorption, salt water ingestion and salt excretion, metabolic water and behavioural adaptations. 7 Hindi Vidya Prachar Samiti’s Ramniranjan Jhunjhunwala College of Arts, Science & Commerce Paper III- Molecular biology, Genetic engineering, Toxicology and Biostatistics Course Code: RJSUZOO503 Total credits: 2.5 Course Objectives: 1. To introduce Molecular Biology of gene alteration and its effects. 2. To understand the tools and