US 200601 02871 A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2006/0102871 A1 Wang et al. (43) Pub. Date: May 18, 2006 (54) NOVELCOMPOSITION 25, 2004, and which is a continuation-in-part of application No. 10/780,045, filed on Feb. 17, 2004, (76) Inventors: Xingwu Wang, Wellsville, NY (US); and which is a continuation-in-part of application No. Howard Greenwald, Rochester, NY 10/747,472, filed on Dec. 29, 2003, and which is a (US); Michael L. Weiner, Webster, NY continuation-in-part of application No. 10/744.543, (US) filed on Dec. 22, 2003, now abandoned, and which is a continuation-in-part of application No. 10/442.420, Correspondence Address: filed on May 21, 2003, now Pat. No. 6,914,412, and Nanoset LLC which is a continuation-in-part of application No. Suite 2490 10/409,505, filed on Apr. 8, 2003, now Pat. No. 349 West Commercial Street 6,815,609. East Rochester, NY 14445 (US) (60) Provisional application No. 60/559,555, filed on Apr. (21) Appl. No.: 11/048,297 5, 2004. (22) Filed: Jan. 31, 2005 Publication Classification Related U.S. Application Data (51) Int. Cl. HOIF I/00 (2006.01) (63) Continuation-in-part of application No. 10/923,579, (52) U.S. Cl. ..................................................... 252A62.51 R filed on Aug. 20, 2004, which is a continuation-in part of application No. 10/914.691, filed on Aug. 9. (57) ABSTRACT 2004, and which is a continuation-in-part of applica tion No. 10/887,521, filed on Jul. 7, 2004, and which A nancomposite material containing nanomagnetic material is a continuation-in-part of application No. 10/867, disposed within a matrix. The nanomagnetic material has a 517, filed on Jun. 14, 2004, and which is a continu saturation magentization of from about 2 to about 3000 ation-in-part of application No. 10/810,916, filed on electromagnetic units per cubic centimeter and contains Mar. 26, 2004, now Pat. No. 6,846,985, and which is nanomagnetic particles with an average particle size of less a continuation-in-part of application No. 10/808,618, than about 100 nanometers; the average coherence length filed on Mar. 24, 2004, and which is a continuation between adjacent nanomagnetic particles is less than 100 in-part of application No. 10/786,198, filed on Feb. nanometerS. 6 11 16 SUBSTRATE 23 1. Patent Application Publication May 18, 2006 Sheet 1 of 25 US 2006/01 02871 A1 g i w r Patent Application Publication May 18, 2006 Sheet 2 of 25 US 2006/01 02871 A1 T TT I I I I I I I IT IN IT 12 TATMTV2E N T N T W A NT INF Sa TS 52 Patent Application Publication May 18, 2006 Sheet 3 of 25 US 2006/01 02871 A1 Patent Application Publication May 18, 2006 Sheet 4 of 25 US 2006/01 02871 A1 o O N g SN s Patent Application Publication May 18, 2006 Sheet 5 of 25 US 2006/01 02871 A1 O O. s O O O O O O O O O. O. O. O. O. O O. O. O. O. O. O. O. O. cooo.O O Patent Application Publication May 18, 2006 Sheet 6 of 25 US 2006/01 02871 A1 CO O V Patent Application Publication May 18, 2006 Sheet 7 of 25 US 2006/01 02871 A1 552 554 546 SUBSTRATE 548 | COANG 556 562 MAGNEIC FIELD GENERATOR 544 SSO 54O. 542 533 N. 2533 536 S38 S25 529 527- 527 S29 531 515 A 517 51 509 N 53 FIG.8 Patent Application Publication May 18, 2006 Sheet 8 of 25 US 2006/01 02871 A1 0/9 (JEITTOHINOO 22 V n N Vad O 999 9/9 Vo SONUNCIONONONOSTNUTNINININOEKONOKOK 999 -|(No.No.TZZ9#99099 No.en Patent Application Publication May 18, 2006 Sheet 9 of 25 US 2006/01 02871 A1 ?y V ym s is Sy S S- L rthis isr isr S.r S.lir LL.nu in f on n t na O t N t t ym - - m in H I N. inN. N. N. N. In N / g?R2s. f / sV s Patent Application Publication May 18, 2006 Sheet 10 of 25 US 2006/01 02871 A1 Patent Application Publication May 18, 2006 Sheet 11 of 25 US 2006/01 02871 A1 OO1 1020 / 1010 XXXXXXX§§ &&&&&&&& }&&&&&&& &&&&&&&& ????&&&& $3&&3&&3333333 §§ §§ ž FIG.16 - 100.or FIG 17 Patent Application Publication May 18, 2006 Sheet 12 of 25 US 2006/01 02871 A1 1045-ooooooooooooooooooO so o o 1025 1020 FIG. 18 /1 OO3 1O3O 1040 1050 O70 1055 1045 1021 FIG.19 Patent Application Publication May 18, 2006 Sheet 13 of 25 US 2006/01 02871 A1 1090 110 107 100 1055 Ng...' ... so...s.. 'e','....d.o.o...a... .o.o 1045-ooooooooooooooooooooo a O 21025 1021 FIG.2O 1030. 1080 105.5 1045 O23 ŽYZ FIG.21 Patent Application Publication May 18, 2006 Sheet 14 of 25 US 2006/01 02871 A1 1025 1023 FIG.22 FIG23 Patent Application Publication May 18, 2006 Sheet 15 of 25 US 2006/01 02871 A1 OO /1 1102 102 1106 Patent Application Publication May 18, 2006 Sheet 16 of 25 US 2006/01 02871 A1 s / Patent Application Publication May 18, 2006 Sheet 17 of 25 US 2006/01 02871 A1 ZOTIT 8Z75TH Patent Application Publication May 18, 2006 Sheet 18 of 25 US 2006/01 02871 A1 Patent Application Publication May 18, 2006 Sheet 19 of 25 US 2006/01 02871 A1 Patent Application Publication May 18, 2006 Sheet 20 of 25 US 2006/01 02871 A1 8IZI DINE5DOARIO dW?ld RIEINAOd EORITMOS 0IZI 00ZI ZOZT Patent Application Publication May 18, 2006 Sheet 21 of 25 US 2006/01 02871 A1 Patent Application Publication May 18, 2006 Sheet 22 of 25 US 2006/01 02871 A1 RIENWOd EOHITOS SOINES)OÅRIOZOZI Patent Application Publication May 18, 2006 Sheet 23 of 25 US 2006/01 02871 A1 AONETOBH+ #78."5DI Patent Application Publication May 18, 2006 Sheet 24 of 25 US 2006/01 02871 A1 i S. Patent Application Publication May 18, 2006 Sheet 25 of 25 US 2006/01 02871 A1 US 2006/01 02871 A1 May 18, 2006 NOVEL COMPOSITION material and a second material selected from the group consisting of a polymeric material, an elastomeric material, CROSS-REFERENCE TO RELATED PATENT a ceramic material, and mixtures thereof. APPLICATIONS 0008. In another embodiment, the mixture also contains 0001. This application is a continuation-in-part of appli halloysite. The nanomagnetic material contains particles cants’ U.S. patent application Ser. No. 10/923,579, filed on with a particle size of from about 3 to about 100 nanometers: Aug. 20, 2004, which in turn was a continuation-in-part of and said particles are at least triatomic, being comprised, of each of applicants copending patent application Ser. No. a first distinct atom, a second distinct atom, and a third 10/914,691 (filed on Aug. 8, 2004), Ser. No. 10/887,521 distinct atom. (filed on Jul. 7, 2004), Ser. No. 10,867.517 (filed on Jun. 14, 2004), Ser. No. 10/810,916 (filed on Mar. 26, 2004), Ser. No. BRIEF DESCRIPTION OF THE DRAWINGS 10/808,618 (filed on Mar. 24, 2004), Ser. No. 10/786,198 (filed on Feb. 25, 2004), Ser. No. 10/780,045 (filed on Feb. 0009. Applicants’ inventions will be described by refer 17, 2004), Ser. No. 10/747,472 (filed on Dec. 29, 2003), Ser. ence to the specification and the drawings, in which like No. 10/744.543 (fled on Dec. 22, 2003), Ser. No. 10/442,420 numerals refer to like elements, and wherein: (filed on May 21, 2003), and Ser. No. 10/409,505 (flied on 0010 FIG. 1 is a schematic illustration, not drawn to Apr. 8, 2003). The entire disclosure of each of these patent scale, of a coated substrate assembly 10 comprised of a applications is hereby incorporated by reference into this Substrate 12 and, disposed thereon, a coating 14 comprised specification. of a multiplicity of nanomagnetic particles 16: 0002 This patent application also claims priority based upon provisional patent application 60/559,555, filed on 0011 FIGS. 2 and 3 schematically illustrate the porosity Apr. 5, 2004, the entire disclosure of which is hereby of the side of coating 14, and the top of the coating 14. incorporated by reference into this specification. depicted in FIG. 1; 0012 FIG. 4 is a schematic illustration of a coated stent FIELD OF THE INVENTION assembly 100: 0003. A mixture comprised of nanomagnetic material and 0013 FIG. 5 is a partial schematic view of a coated stent a second material selected from the group consisting of a assembly 200; polymeric material, an elastomeric material, a ceramic mate rial, and mixtures thereof. 0014 FIG. 6 is a schematic of one preferred sputtering process; BACKGROUND OF THE INVENTION 0.015 FIG. 7 is a partial schematic of one preferred 0004 Applicants have been awarded several United particle collection process; States patents that describe nanomagnetic material. These include U.S. Pat. No. 6,506.972 (“Magnetically shielded 0016 FIG. 8 is a schematic of a plasma deposition conductor”), U.S. Pat. No. 6,673,999 (“Magnetically process; shielded assembly”), U.S. Pat. No. 6,713,671 (“Magneti 0017 FIG. 9 is a schematic of one preferred forming cally shielded assembly”), U.S. Pat. No. 6,765,144 (“Mag netic resonance imaging coated assembly'), U.S. Pat.