Table of contents Executive Summary Chapter 1 – Introduction Chapter 2 – Trends in drug delivery dealmaking 2.1. Introduction 2.2. Drug delivery partnering over the years 2.3. Bigpharma drug delivery dealmaking activity 2.4. Big biotech drug delivery dealmaking activity 2.5. Most active drug delivery dealmakers 2.6 Drug delivery partnering by deal type 2.7. Drug delivery partnering by disease type 2.8. Partnering by drug delivery technology type 2.9. Average deal terms for drug delivery partnering 2.9.1 Drug delivery headline values 2.9.2 Drug delivery upfront payments 2.9.3 Drug delivery milestone payments 2.9.4 Drug delivery royalty rates 2.10. The anatomy of drug delivery partnering 2.11. Drug delivery or specialty pharma? 2.11.1. Is specialty pharma the only way for drug delivery? 2.11.2. Best practice for optimizing drug delivery program development 2.11.3. The anatomy of a drug delivery deal 2.11.3.a. Case study 1: Alpharma – Durect 2.11.3.b. Case study 2: Bayer – MDRNA 2.11.3.c. Case study 3: Endo Pharmaceuticals – BioDelivery Sciences Chapter 3 – Leading drug delivery deals 3.1. Introduction 3.2. Top drug delivery deals by value Chapter 4 – Bigpharma drug delivery deals 4.1. Introduction 4.2. How to use bigpharma drug delivery partnering deals 4.3. Big pharma drug delivery partnering company profiles Abbott Actavis Inc (formerly Watson Pharmaceuticals) Actavis (merged with Watson Pharmaceuticals Oct 2012) Actelion Allergan Amgen Astellas AstraZeneca Baxter International Bayer Biogen Idec Boehringer Ingelheim Bristol-Myers Squibb Celgene CSL Daiichi Sankyo Dainippon Sumitomo Eisai Eli Lilly Endo Pharmaceuticals Forest Laboratories Galderma Gilead Sciences GlaxoSmithKline Grifols Hospira Johnson & Johnson Kyowa Hakko Kirin Lundbeck Menarini Merck & Co Merck KGaA Mylan Novartis Novo Nordisk Otsuka Pfizer Purdue Roche Sanofi Shionogi Shire Takeda Teva UCB Valeant Warner Chilcott Chapter 5 – Bigbiotech drug delivery deals 5.1. Introduction 5.2. How to use bigbiotech partnering deals 5.3. Bigbiotech drug delivery partnering company profiles Actelion Acorda Therapeutics Alexion Pharmaceuticals Alkermes Alnylam Pharmaceuticals AMAG Pharmaceuticals Amgen Amylin Pharmaceuticals Biocon BioCryst Pharmaceuticals Biogen Idec Biota Holdings BioMarin Pharmaceuticals Cangene Celgene CSL Cubist Elan Emergent BioSolutions Enzon Pharmaceuticals Gilead Sciences Immunomedics Intermune Isis Pharmaceuticals Morphosys Nektar Therapeutics NPS Pharmaceuticals PDL BioPharma Roche SciClone Pharmaceuticals Seattle Genetics Spectrum Pharmaceuticals The Medicines Company UCB Vertex Pharmaceuticals ViroPharma Chapter 6 – Drug delivery partnering contracts directory 6.1. Introduction Anesiva Biomedical Advanced 6.2. Company A-Z Anesta Research and 3M Angiodynamics Development Authority 3M Drug Delivery Systems Angiotech BioMerieux 3SBio Pharmaceuticals BioMimetic Therapeutics Abbott Laboratories AnorMed Biopure Abraxis BioScience AP Pharma BioSante Pharmaceuticals Accentia Aradigm BioSpecifics Technologies Biopharmaceuticals Aristos Pharmaceuticals Biovail Accredo Health Group Arius Pharmaceuticals Biovail Laboratories Acorda Therapeutics ArQule BioVest Actavis Arrow International BioZone Laboratories Actient Pharmaceuticals ARYx Therapeutics Brand Builders Acura Pharmaceuticals Astellas International Acusphere AstraZeneca Brand Builders Rx Adams Respiratory Atley Pharmaceuticals Breath Therapeutics Auxilium Pharmaceuticals Bristol-Myers Squibb Adeona Pharmaceuticals AVANT Brookwood Adolor Immunotherapeutics Pharmaceuticals Advanced Life Sciences AVI Pharma Brotech Alchemia Azur Pharma Caleco Pharma Alexion Pharmaceuticals Banner Pharmacaps Caleco Pharma Europe Alexza Pharmaceuticals Barrier Therapeutics Callisto Pharmaceuticals Alfacell Bausch & Lomb Cambridge Laboratories Alimera Sciences Baxter Healthcare Caraco Pharmaceuticals Alkermes Baxter Oncology GmbH Cardinal Health Allergan Bayer Cardium Therapeutics Allos Therapeutics Bayer Healthcare Cary Pharmaceuticals Alnylam Pharmaceuticals Ben Venue Laboratories Catalent Pharma Solutions Alpharma Bentley Pharmaceuticals Cato BioVentures Alpharma Ireland Biken Celsion Altus Pharmaceuticals BioAlliance Pharma Cephalon Amag Pharmaceuticals BioArray Solutions Cepheid Amarillo Biosciences BioCryst Pharmaceuticals Cerus Amarin BioDelivery Sciences Chrysalis Technologies Amicus Therapeutics Biofield Clarus Therapeutics Ampio Pharmaceuticals Biogen Idec Coating Place Amylin Pharmaceuticals BiolineRX CollaGenex Anacor Pharmaceuticals Columbia Laboratories ANDRx CombinatoRx Contract Pharmaceuticals Emergent BioSolutions Imprimis Pharmaceuticals Control Delivery Systems Emisphere Inalco Biochemicals CorMedix Endo Pharmaceuticals Inalco Group Cornerstone Biopharma Enzon Pharmaceuticals Incyte Cornerstone Therapeutics Epic Pharmaceuticals Indevus Pharmaceuticals Cortex Pharmaceuticals EpiCept Inex Pharmaceuticals Cosmo Technologies Esprit Pharma Inovio Pharmaceuticals Cowen Healthcare Royalty Evonik Industries InSite Vision Partners Facet Biotechnology Insmed Inc CP Pharmaceuticals Ferndale Pharmaceuticals Inspire Pharmaceuticals CPEX Pharmaceuticals Finorga Institut Biochimique Crawford Healthcare Fleet Laboratories Intas Biopharmaceuticals Critical Therapeutics Flynn Pharma IntelGenx Cubist Pharmaceuticals Forbes Medi-Tech Intendis Cumberland Fovea Pharmaceuticals Intergen Pharmaceuticals Genaera InterMune CV Therapeutics Genentech Ipsen CyDex Generex Biotechnology ISTA Pharmaceuticals Cypress Bioscience Genta Ivax Daewoong Pharmaceutical GenVec Jagotec Daiichi Sankyo Genzyme Javelin Pharmaceuticals Dainippon Sumitomo Ghent University Jazz Pharmaceuticals Pharma GlaxoSmithKline JDS Pharmaceutical Dalian Wande Electronics GlobeImmune JHP Pharmaceuticals Dechra Veterinary GPC Biotech Jiangsu Yabang Products Graceway Pharmaceuticals Defense Threat Reduction Pharmaceuticals Johns Hopkins University Agency Green Vision Johnson & Johnson Dehaier Medical Systems Grunenthal JPI Commercial Department of Homeland Hadasit Medical Research KCI International Security Services and Development Kensey Nash DepoMed Halozyme Therapeutics Keryx Biopharmaceuticals Desitin Hangzhou Zhencheng King Pharmaceuticals Dey Pharma Pharmaceuticals Kiwa Bio-Tech Products Diomed Hebei Huaxing Klarogen Biotherapeutics Discovery Laboratories Pharmaceuticals Kunwha Pharmaceuticals DoctorDirectory Hebei Kiwa Huaxing Bio- KV Pharmaceutical DOR BioPharma Pharmaceuticals Kyowa Hakko Kogyo Dov Pharmaceutical Helix BioMedix Kythera Dow Pharmaceutical Helix BioPharma Biopharmaceuticals Sciences HemispheRx Biopharma Lees Pharmaceutical DPT Laboratories Heraeus Lenetix Draxis Pharma Hermes BioScience Ligand Pharmaceuticals Drugs for Neglected Horizon Pharma AG Lonza Diseases Initiative Horizon Pharma Inc Los Angeles Biomedical Duramed Hospira Research Institute Durect Hunan Jiuwang Lung Rx DUSA Pharmaceuticals Pharmaceuticals Lupin Pharmaceuticals Dyax Hydron Technologies Macrochem Echo Therapeutics Idea Mallinckrodt ECR Pharmaceuticals IDIS Pharma MAP Pharmaceuticals EDK Therapeutics Ikaria Marina Biotech EKR Therapeutics ImaRX Massachusetts Institute of Elan ImClone Systems Technology Eli Lilly Immunomedics McCoy Enterprises Elite Pharmaceuticals Impax Laboratories McKesson McNeil PPC Novasep PSivida MD Anderson Cancer Noven Pharmaceuticals Purdue Pharma Center Novo Nordisk QLT MDRNA Novozymes Biopharma QLT USA Meda NuGlow Cosmaceuticals QuatRx Pharmaceuticals Medgenics NuPathe Radius Health Medical Futures Nycomed Rechon Life Sciences MediciNova Obagi Medical Products Reckitt Benckiser Medicis Ocimum Biosolutions RedHill Biopharma Medtronic Oculus Innovative Repligen Meiji Seika Sciences RevImmune Memorial Sloan Kettering Oklahoma Medical Rib-X Pharmaceuticals Cancer Center Research Foundation Rigel Pharmaceuticals Memory Pharmaceuticals OncoSec Medical Roche Menarini Ono Pharmaceutical Rodan and Fields Merck and Co Ophthalmic Research Rohto Pharmaceuticals Merial Associates Royalty Securitization Merrimack Oradisc Trust Pharmaceuticals Oramed Pharmaceuticals S2 Therapeutics Mglas Ore Pharmaceuticals Sagent Pharmaceuticals Microbix Biosystems Orexigen Therapeutics Salix Pharmaceuticals MiddleBrook Orion Sam Amer Pharmaceutical Oso Bio Pharmaceuticals Sangamo BioSciences Mikah Pharma Pacific Beach Biosciences Sanofi-Aventis Millennium Pacira Pharmaceuticals Santarus Mist Acquisition Paladin Labs Santen Pharmaceutical Mova Pharmaceuticals Panion Savient Pharmaceuticals Mundipharma Par Pharmaceutical Schering-Plough Mutual Pharmaceutical Paramount Biosciences Scolr Pharma Mylan Laboratories Patheon Seattle Genetics National Institute of Allergy PDL BioPharma Select Vaccines and Infectious Diseases Pfizer Senetek National Institute of Pharmaceutical Sepracor Infectious Diseases Innovations Sequenom ND Partners Pharmacopeia Serenity Pharmaceuticals Nektar Therapeutics PharmaEngine Shaanxi Aoxing Neos Therapeutics Philip Morris Products Pharmaceutical NeurogesX Pipex Pharmaceuticals Shaanxi Jiali Neurokine Polymun Scientific Pharmaceuticals Pharmaceuticals Immunbiologische Shandong Yaoshan Neuromed Poniard Pharmaceuticals Pharmaceuticals NeuroMed Devices Porex Shijiazhuang-Unigene Neuronex Pozen Pharmaceuticals NexMed Prasco Laboratories Shijiazhuang Nitec Pharma Precision Pharma Pharmaceutical NitroMed Services Shionogi Nof Prestige Brands Shire Pharmaceuticals Norgine Procter & Gamble SIGA Technologies Northern Lipids Procter & Gamble Sigma-Aldrich Nova Biomedical Pharmaceuticals Sigma-Tau NovaBay Pharmaceuticals Professional SignPath Pharmaceuticals