The Henry Kunkel Society Annual Meeting: Infectious Disease Susceptibility and the Expanding Universe of Primary Immunodeficiency The Rockefeller University New York, NY April 17–20, 2013 Henry George Kunkel 1916–1983 enry Kunkel received his B.S. degree from Princeton and his M.D. degree from Johns Hopkins University. He arrived at The Rockefeller Institute (now University) in 1945 where he spent his entire scientific career H until his death in 1983. His contributions to the field of basic and clinical immunology are legendary. He made numerous seminal observations in liver disease, rheumatic diseases and other allied disorders. He was perhaps best known for his pioneering and extensive studies on the immunoglobulins. His recognition that myeloma proteins were a model for the study of the structure of normal immunoglobulins had a global impact on investigations of the structure, function and inheritance of these molecules. The elucidation of the chain structure of gamma globulin and the recognition that immunoglobulins possessed individual antigenic specificity (idiotypes) were internationally recognized discoveries. Dr. Kunkel was the recipient of many awards and honors, including membership in the National Academy of Sciences, honorary degrees from Universities of Uppsala and Harvard, and recipient of the Lasker and Gairdner Awards and the Kovalenko Medal of the National Academy of Sciences. Henry Kunkel Society Officers Henry Kunkel Society Lecturers President ................Westley Reeves 1992. Louis Kunkel 2003. .Fred Rosen Vice President ...............Keith Elkon 1993. .David Ho 2004. .Diane Mathis Secretary ........... Michel Nussenzweig 1994. Benvenuto Pernis 2005. Charles Weissman Treasurer ...............Anne Marshak- 1996. Jeffrey Ravetch 2006. Ralph M. Steinman Rothstein 1997. Anthony Fauci 2007. Antonio Lanzavecchia 1998. Klaus Rajewsky 2008. John Atkinson 1999. .Peter Doherty 2009. Thomas Tuschl 2000. Max D. Cooper 2010. Frederick Alt 2001. Fritz Melchers 2011. Mark M. Davis 2002. Tasuku Honjo 2012. .Louis M. Staudt Henry Kunkel Society Members Sergio Abrignani Ira Berkower Michael Centola Rajendra Damle Luciano Adorini Robert D. Bigler, II Anthony Cerami Franco Dammacco Vincent Agnello Richard S. Blumberg Andrea Cerutti Robert B. Darnell Irma Airold Linda K. Bockenstedt Ethel Cesarman Anne Davidson Arne N. Akbar Bjarne Bogen Edward K. L. Chan Randall S. Davis Donato Alarcon-Segovia# Stefano Bombardieri Andrew Chan Noorbibi K. Day Matthew Albert Constantin A. Bona George K. Chandy Jean-Michel Dayer Mara Luisa (Marisa) Alegre Jerry Boss† Lucienne Chatenoud Silvia Deaglio Konstantina Alexandropoulos† Marina Botto Talal Chatila Paolo Dellabona Paul Allen† Vassiliki A. Boussiotis† Triantafyllos Chavakis Stephen V. Desiderio Chester A. Alper Jean-Pierre Bouvet Youhai Chen Kavita Dhodapkar Sebastian Amigorena Joseph Boyle Selina Chen-Kiang Madhav V. Dhodapkar Ulf Anderson Thomas J. Braciale Nicholas Chiorazzi Betty A. Diamond Paul J. Anderson Ferdinand C. Breedveld Francis V. Chisari Howard Dickler Francesco Annuziato Michael Brenner Carlo Chizzolini Guillermo Dighiero William P. Arend Stanley Louis Bridges Charles Christian Teresa P. DiLorenzo Joseph R. Arron Thomas Brocker Charles Chu Walter H. Doerfler John P. Atkinson Eric Brown Marcus Ramsay Clark Peter C. Doherty K. Frank Austen Teodor-Boru Brumeanu Edward A. Clark Thomas Dörner Stratis Avrameas Gerd-Rudiger Burmester Charles Cochrane Daniel Douek Raffaele Badolato Joel Buxbaum Richard Coico Steven Douglas David Bahler Jill Buyon Mary Ellen Conley Terry William Du Clos Vincenzo Barnaba John C. Byrd Gabriela Constantin Anne Durandy Craig Bassing Michael Cahalan H. Terence Cook George Ebers Antony Basten Federico Caligaris-Cappio David Cooper Dimitar G. Efremov Ekkehard K. F. Bautz Michael P. Cancro Max D. Cooper Michael Ehrenstein Alexander Bearn# Daniela Capello Andrew P. Cope Götz Ehrhardt Timothy W. Behrens J. Donald Capra Joseph Craft Klaus Eichmann Baruj Benacerraf# Ronald I. Carr Carlo M. Croce Robert A. Eisenberg J. Claude Bennett Michael C. Carroll Alan Cross Hani El-Gabalawy Christophe O. Benoist Robert H. Carter Mary K. Crow Keith Elkon Zvi Bentwich Paolo Casali Charlotte Cunningham- Anna Erdei† Claudia Berek Jean-Laurent Casanova Rundles Doruk Erkan Kâre Berg Rafael Casellas Riccardo Dalla-Favera Luis R. Espinoza Paul Evans Richard J. Hodes Lloyd Mayer Marko Z. Radic Norman Talal Zsuzsa Fabry V. Michael Holers Maclyn McCarty# Kanti R. Rai Eng M. Tan Andras Falus Steven M. Holland James McCluskey Klaus Rajewsky Stuart Tangye Donna L. Farber Halsted R. Holman Joseph (Mike) McCune Joyce Rauch Alexander Tarakhovsky A. Darise Farris David Horn A. McGehee Harvey Jeffrey Ravetch Kristin Tarbell C. Garrison Fathman Alan N. Houghton Victor McKusick Stanley Read Naomi Taylor Douglas Thomas Fearon Thomas W. J. Huizinga Ruslan Medzhitov Ann Reed Francesco Tedesco Ten Feizi Mary Beth Humphrey Eric Meffre Westley H. Reeves Cox Terhorst Marc Feldmann John Hurley# Fritz Melchers Morris Reichlin Argyrios N. Theofilopoulos Gianfranco Ferraccioli David A. Isenberg Elizabeth D. Mellins Bernardo Reina- Robert Thoburn Manlio Ferrarini Kimishige Ishizaka Henri Menard San Martin Adrian Thrasher Erol Fikrig Lionel B. Ivashkiv Miriam Merad Maria Rescigno Angela Tincani Terri Finkel Bana Jabri Pier Luigi Meroni Michael Reth Thomas Tomasi Alison Finnegan Hans-Martin Jäck Joan T. Merrill Lisa G. Rider Kevin J. Tracey Gary S. Firestein Chaim Oscar Jacob Jiri Mestecky Frederic Rieux-Laucat Elisabetta Traggiai Vincent Fischetti Israeli Jaffe Christine Metz William C. Robbins Edward L. Treadwell Zvi Fishelson Ashish Jain† Dror Mevorach William Robinson Giorgio Trinchieri David E. Fisher Judith A. James Mary Ann Michelis Toby Rodman Jurg Tschopp# Richard A. Flavell Roland Jonsson Peter A. Miescher Martin Rodriguez George Tsokos Thomas A Fleisher Dieter Kabelitz Fred Miller Santiago Rodriguez Naoyuki Tsuchiya Ira J. Fox Joachim R. Kalden Eric C. B. Milner de Cordoba Shannon Turley Marvin Fritzler Insoo Kang Toshihide Mimura Axel Roers Antonio Uccelli Yang-Xin Fu Fu Gilla Kaplan Seiji Minota Lars Rönnblom Jonathan W. Uhr Shu Man Fu Mikael Karlsson Pierre Miossec† Antony Rosen Raivo Uibo Herman Fudenberg Jonathan D. Katz Chandra Mohan Fred Rosen# Emil R. Unanue Sarah L. Gaffen Michel D. Kazatchkine Tom Eirik Mollnes Agueda A. Rostagno Derya Unutmaz Patrick Gaffney Jack D. Keene Patricia K. A. Mongini Thomas Rothstein Jacques Urbain Gianluca Gaidano Robert Kimberly Laurence Morel Robert A. S. Roubey Paul J. Utz Thomas F. Gajewski Paul W. Kincade Lorenzo Moretta Robert L. Rubin Anders G. Vahlne Uri Galili Thomas Kindt Jane Morse# Alexander Y. Rudensky Andrea Vambutas Ignacio Garcia- Te Piao King Bernard Moser Carlo Russo Wesley C. Van Voorhis De La Torre Michael Kirschfink William A. Muller Federica Sallusto Charles S. Via Hubert Baburaj (Bobby) Lars Klareskog Hans Muller-Eberhard# Jane E. Salmon Anna Villa Gasper† Kim L. Kline Kenneth Murphy Hugh A. Sampson Herbert W. Virgin Raif S. Geha Glen Knight Philip M. Murphy Inger Sandlie Ulrich H. Freiherr James L. German, III Daniel M. Knowles Natarajan Muthusamy Matyas Sandor von Andrian-Werburg M. Eric Gershwin Hon-Sum Ko Bertrand Nadel Laura Santambrogio Harald von Boehmer Paolo Ghia Alisa E. Koch Carl F. Nathan Ignacio Sanz Takaji Wakita Allan Gibofsky David Koffler# Jacob B. Natvig Minoru Satoh Thomas A. Waldmann Irma Gigli Frits Koning Gerald Thomas Nepom David Schatz† Herman Waldmann Gray Steven Gilkeson Dwight H. Kono Janko Nikolich-Zugich Georg Schett Mark Jeremy Walport Martin John Glennie Philippe H. A. Kourilsky Kenneth Nilsson Claudine Schiff Chang-Yi Wang Laurie Glimcher Michael Krangel Falk Nimmerjahn Reinhold Schmidt† Jingsong Wang Otto Goetze Richard Krause Douglas F. Nixon Robert Schreiber† H. Shaw Warren Leslie Gold Karsten Kretschmer† Gustav J. V. Nossal Harry W. Schroeder, Jr. Richard L. Wasserman Raphaela Goldbach- James G. Krueger Luigi D. Notarangelo Peter H. Schur Martin Weigert Mansky Vijay Kuchroo Jan Novak R. Hal Scofield Jean-Claude Weill† Robert A. Good# Dinakantha Kumararatne Victor Nussenzweig Gavin Screaton Marc Weksler Tom Gordon Steven Kunkel Michel C. Nussenzweig Benjamin M. Segal Hans Ulrich Weltzien Siamon Gordon Louis Kunkel Hans D. Ochs Andrey Shaw† Peter P. Wernet Jorg J. Goronzy Antonio La Cava Lloyd Old Barbaray Sherry Per Westermark Emil C. Gotschlich Peter J. Lachmann Michael B. A. Oldstone Yufang Shi Cornelia M. Weyand Susan R. S. Gottesman Robert G. Lahita Eugene Oltz Mark Jay Shlomchik Juergen Wienands Alice B. Gottlieb Antonio Lanzavecchia Jordan Scott Orange† Frederick P. Siegal David Wiest† Ellen M. Gravallese Terri Laufer Anders Orn Leslie E. Silberstein Ralph C. Williams, Jr. Arthur Grayzel Jeffery A. Ledbetter Barbara Anne Osborne Gregg Silverman Patrick C. Wilson Mark Grebenau David M. Lee C. Kirk Osterland Roy L. Silverstein Robert J. Winchester Mark I. Greene Paul J. Lehner Mario A. Ostrowski Franco Silvestris John Winfield Howard M. Grey Beth Levine Shoichi Ozaki Alfred Singer Jedd Wolchok Bodo Grimbacher Peter Lipsky Stephen A. Paget Ram Singh Kevin Woollard† Luca Guidotti Sergio A. Lira Savita Pahwa Francesco Sinigaglia Kai W. Wucherpfennig Sudhir Gupta Gary W. Litman Eric G. Pamer John Patrick Sissons Ramnik Xavier David A. Hafler Stephen Litwin Sunpho Park Marjorie Slankard Kazuhiko Yamamoto Kathleen A. Haines Yang Liu Virginia Pascual Barry Sleckman William Yount William W. Hall Miguel Lopez-Botet Dhavalkumar D. Patel Kendall Smith John Zabriskie Lars Hanson Pier Luigi Luigi