FEBSSysBio2007: Advanced Lecture Course on Systems Biology, Gosau 2nd FEBS Advanced Lecture Course on Systems Biology: From Molecules to Life Gosau, Austria, EU, March 10-16, 2007 Organizers Karl Kuchler Medical University Vienna Max F. Perutz Laboratories Campus Vienna Biocenter Edda Klipp Computational Systems Biology Max-Planck Institute for Molecular Genetics Berlin Uwe Sauer Institute for Molecular Systems Biology ETH Zürich Hans V. Westerhoff (program chair) AstraZeneca Chair for Systems Biology, Manchester Centre of Integrative Systems Biology, The University of Manchester and Department of Molecular Cell Physiology, Netherlands Institute for Systems Biology, Free University Amsterdam Anneke (J.G.) Koster (course secretary) Institute for Systems Biology Amsterdam Walter Glaser (IT) Medical University Vienna Max F. Perutz Laboratories Campus Vienna Biocenter Introduction FEBSSysBio2007: Advanced Lecture Course on Systems Biology, Gosau Teachers Alan Aderem Jeroen Jeneson Steve Oliver Lilia Alberghina Tom Kirkwood Johan Paulsson Judy Armitage Hiroaki Kitano Uwe Sauer Barbara Bakker Ursula Klingmüller Johannes Schlöder Frank Bruggeman Edda Klipp Guy Shinar Marta Cascante Karl Kuchler Jacky Snoep Marileen Dogterom Ursula Kummer Jaroslav Stark Måns Ehrenberg Doug Lauffenburger Jens Timmer Igor Goryanin Hans Meinhardt Hans van Leeuwen Adriano Henney Erik Mosekilde Nathal van Riel Jannie Hofmeyr Bela Novak Hans V. Westerhoff Leroy Hood Jens Nielsen Other Members of the Scientific Advisory Board Ruedi Aebersold Douglas Kell Roel van Driel Uri Alon Boris Kholodenko Barry Wanner Roland Eils Sang Yup Lee Shoshana Wodak Stefan Hohmann Bernard Palsson Mariko Hatakeyama Masaru Tomita Technical Support & Registration & Course Office FEBS- Sysbio Course Office: Anneke (J.G.) Koster Amsterdam Systems Biology Institute CharlieParkerstraat 25 NL-1066GV Amsterdam, EU Phone: +31-20-6143163 FAX: +31-20-6143163 email: systems.biology [at] inter.nl.net wwweb: http://www.febssysbio.net and http://www.univie.ac.at/sysbio2007/ At the Venue in Gosau: Anneke (J.G.) Koster Sport undErlebnis Hotel**** Gosau A-4824Gosauam Dachstein713, Austria, EU Phone: +43-6136-8811-390 FAX: +43-6136-8811-352 email: systems.biology [at] inter.nl.net wwweb: http://www.febssysbio.net and http://www.univie.ac.at/sysbio2007/ FEBS-SysBio2007 Hotlines: +43 676 5842185 (ReginaKlaus) and+316520 76384 (Anneke Koster) 2 The Course contents: FEBSSysBio2007: Advanced Lecture Course on Systems Biology, Gosau Organizing institutions Main Organizer: FEBS: FEBS-SysBio2007, the 2 nd A dvanced Lecture Course on Systems Biology is organized on behalf of FEBS, the Federation of European Biochemical Societies. Co-organizing networks from the EC-FP6 programme: YSBN: Yeast Systems Biology Network, a Coordination Action on Yeast Systems Biology co-organized the Yeast Symposium. BioSim: A Network of Excellence for BioSimulation co-organized the Tools and Methods Symposium. NucSys: A Marie Curie Training Network entitled "Systems biology of nuclear receptors: a nutrigenomic approach to aging-related diseases" co-organized the Mammalian Systems Biology Symposium Other co-organizing network: SBForum: The Scottish Bioinformatics Forum. Integrating the Bioinformati cs and Life Science research comminities, sponsors the computer/balck board workshop on the Edinburgh Pathway Editor by Goryanin and SorokinYeast Systems Biology Network, a Coordination Action on Yeast Systems Biology co-organized the Yeast Symposium. Program, abstracts and participant’s notes 3 FEBSSysBio2007: Advanced Lecture Course on Systems Biology, Gosau FEBS-SysBio2007 was supported by FEBS [The Federation of the European Biochemical Societies] YSBN: Yeast Systems Biology Network BMBF [German Bundesministerium für Bildung und Forschung] BioSim Network of Excellence on BioSimulation AstraZeneca DKFZ [Deutsche Krebsforschungszentrum] DSM BioCentrum Amsterdam The Scottish Bioinformatics Forum European Society for Mathematical and Theoretical Biology 4 FEBSSysBio2007: Advanced Lecture Course on Systems Biology, Gosau Helios Biosciences: an SME for target discovery through Systems Biology Unilever Cosmetics Doctoral Training Centre for Integrative Systems Biology from Molecules to Life FEBS Journal Amsterdam Systems Biology Institute EML (European Media Laboratory) Program, abstracts and participant’s notes 5 FEBSSysBio2007: Advanced Lecture Course on Systems Biology, Gosau Table of Contents Organizers ......................................................................................................................................................... 1 Teachers ............................................................................................................................................................ 2 Other Members of the Scientific Advisory Board............................................................................................... 2 Technical Support & Registration & Course Office............................................................................................ 2 Organizing institutions ....................................................................................................................................... 3 Main Organizer: .......................................................................................................................................... 3 Co-organizing networks from the EC-FP6 programme: ............................................................................. 3 Other co-organizing network: ..................................................................................................................... 3 FEBS-SysBio2007 was supported by................................................................................................................ 4 Willkommen in Gosau, Welkom in Gosau, Welcome to Gosau! ....................................................................... 7 Scientific Program - its principles..................................................................................................................... 12 Symposia...................................................................................................................................................... 12 Symposia Morning: Lectures (L), tutorials and an issues identifiying discussion ........................................ 12 Break for Lunch, Physical Activities, Tea..................................................................................................... 12 Black-Board Teaching (BB).......................................................................................................................... 12 Computer practicals (CP)............................................................................................................................. 13 Symposia afternoon: Short Talks (S) ........................................................................................................... 13 Symposia late afternoon discussion............................................................................................................. 13 Poster Presentations (P), Poster Committees, Analyses, Discussions ....................................................... 14 Participant Task List: Contribution of each Participant and its Timing ............................................................ 15 The Course Book - its Principles ..................................................................................................................... 19 Abstracts ...................................................................................................................................................... 19 Course (‘Abstract’) Book - Paper ................................................................................................................. 19 Course (‘Abstract’) Book - Electronic ........................................................................................................... 19 Systems Biology Young Investigator Awards .................................................................................................. 19 Web Site....................................................................................................................................................... 19 Technical Local Information............................................................................................................................. 20 Connections – You and the World ............................................................................................................... 20 Internet – You and the World ....................................................................................................................... 20 Departure ..................................................................................................................................................... 20 FEBS Evaluation Form................................................................................................................................. 20 FEBS-SysBio2005 Course Office ................................................................................................................ 20 Help .............................................................................................................................................................. 21 Message Board ............................................................................................................................................ 21 Meals, Beverages & Lunch