Motivational Disorders Reading List 2017 | Sanjay Manohar Reviews Suggested core reading Husain & Schott “Cognitive Neurology” Chapter 19, Neuropsychiatric aspects of cognitive impairment Voon V, Mehta AR, and Hallett MD, “Impulse control disorders in Parkinson’s disease: recent advances”, Current Opinion in Neurology (2011) Starkstein SE and Leenthens AFG, “The nosological position of apathy in clinical practice” Other reviews Kranick SM and Hallett MD, “Neurology of Volition”, Exp Brain Res 2013 Sep; 229(3):313-327 Rothkirch, Marcus, and Philipp Sterzer. “The role of motivation in visual processing.” Motivation and Cognitive Control, 2015, 23. Brown, Richard G., and Graham Pluck. “Negative Symptoms: The ‘Pathology’ of Motivation and Goal- Directed Behaviour.” Trends in Neurosciences 23, no. 9 (September 1, 2000): 412–17. Original papers Impulse Control Disorders Sinha, N, Manohar S, and Husain M. “Impulsivity and Apathy in Parkinson’s Disease.” Journal of Neuropsychology, 2013, n/a–n/a. https://doi.org/10.1111/jnp.12013. Review of how the two might relate Clark, L., A. Bechara, H. Damasio, M. R. F. Aitken, B. J. Sahakian, and T. W. Robbins. “Differential Effects of Insular and Ventromedial Prefrontal Cortex Lesions on Risky Decision-Making.” Brain 131, no. 5 (May 1, 2008): 1311–22. https://doi.org/10.1093/brain/awn066. Cambridge Gambling task in prefrontal patients Bechara, Antoine, Daniel Tranel, and Hanna Damasio. “Characterization of the Decision- Making Deficit of Patients with Ventromedial Prefrontal Cortex Lesions.” Brain 123, no. 11 (November 1, 2000): 2189–2202. https://doi.org/10.1093/brain/123.11.2189. The Iowa Gambling Task Obeso, Ignacio, Leonora Wilkinson, Enrique Casabona, Maria Luisa Bringas, Mario Álvarez, Lázaro Álvarez, Nancy Pavón, et al. “Deficits in Inhibitory Control and Conflict Resolution on Cognitive and Motor Tasks in Parkinson’s Disease.” Experimental Brain Research 212, no. 3 (July 1, 2011): 371–84. https://doi.org/10.1007/s00221-011-2736-6. Disinhibition in PD? Wildenberg, Wery P. M. van den, Geert J. M. van Boxtel, Maurits W. van der Molen, D. Andries Bosch, Johannes D. Speelman, and Cornelis H. M. Brunia. “Stimulation of the 1 Subthalamic Region Facilitates the Selection and Inhibition of Motor Responses in Parkinson’s Disease.” Journal of Cognitive Neuroscience 18, no. 4 (April 1, 2006): 626– 36. https://doi.org/10.1162/jocn.2006.18.4.626. STN DBS improves stopping in PD Lang, Anthony E., Antonio P. Strafella, Bénédicte Ballanger, Giovanna Pellecchia, Janis M. Miyasaki, and Thilo van Eimeren. “Dopamine Agonists Diminish Value Sensitivity of the Orbitofrontal Cortex: A Trigger for Pathological Gambling in Parkinson’s Disease?” Neuropsychopharmacology 34, no. 13 (December 2009): 2758. https://doi.org/10.1038/npp.2009.124. Increased gambling in PD associated with altered RPE in OFC Cools, Roshan, Roger A Barker, Barbara J Sahakian, and Trevor W Robbins. “L-Dopa Medication Remediates Cognitive Inflexibility, but Increases Impulsivity in Patients with Parkinson’s Disease.” Neuropsychologia 41, no. 11 (January 1, 2003): 1431–41. https://doi.org/10.1016/S0028-3932(03)00117-9. Berlin, H. A., E. T. Rolls, and U. Kischka. “Impulsivity, Time Perception, Emotion and Reinforcement Sensitivity in Patients with Orbitofrontal Cortex Lesions.” Brain 127, no. 5 (May 1, 2004): 1108–26. https://doi.org/10.1093/brain/awh135. Impulsivity in decision making after frontal lesions Djamshidian, Atbin, Sean S. O’Sullivan, Yanosh Sanotsky, Stephen Sharman, Yuriy Matviyenko, Thomas Foltynie, Rosanna Michalczuk, et al. “Decision Making, Impulsivity, and Addictions: Do Parkinson’s Disease Patients Jump to Conclusions?” Movement Disorders 27, no. 9 (August 1, 2012): 1137–45. https://doi.org/10.1002/mds.25105. “Beads task” for information seeking Apathy Adam, Robert, Alexander Leff, Nihal Sinha, Christopher Turner, Paul Bays, Bogdan Draganski, and Masud Husain. “Dopamine Reverses Reward Insensitivity in Apathy Following Globus Pallidus Lesions.” Cortex 49, no. 5 (May 1, 2013): 1292–1303. https://doi.org/10.1016/j.cortex.2012.04.013. Effect of lesions in basal ganglia Chong, Trevor T. -J., Valerie Bonnelle, Sanjay Manohar, Kai-Riin Veromann, Kinan Muhammed, George K. Tofaris, Michele Hu, and Masud Husain. “Dopamine Enhances Willingness to Exert Effort for Reward in Parkinson’s Disease.” Cortex 69, no. Supplement C (August 1, 2015): 40–46. https://doi.org/10.1016/j.cortex.2015.04.003. Physical force exertion for reward as a measure of motivation Rochat, Lucien, Martial Van der Linden, Olivier Renaud, Jean-Benoît Epiney, Patrik Michel, Roman Sztajzel, Lucas Spierer, and Jean-Marie Annoni. “Poor Reward Sensitivity and Apathy after Stroke Implication of Basal Ganglia.” Neurology 81, no. 19 (November 5, 2013): 1674–80. https://doi.org/10.1212/01.wnl.0000435290.49598.1d. Monetary incentive delay task Volition & Goal-directed behavior Guitton, D., H. A. Buchtel, and R. M. Douglas. “Frontal Lobe Lesions in Man Cause Difficulties in Suppressing Reflexive Glances and in Generating Goal-Directed Saccades.” Experimental Brain Research 58, no. 3 (May 1, 1985): 455–72. https://doi.org/10.1007/BF00235863. Measuring goal-directed behaviour in eye movements Duncan, John, Hazel Emslie, Phyllis Williams, Roger Johnson, and Charles Freer. “Intelligence and the Frontal Lobe: The Organization of Goal-Directed Behavior.” Cognitive 2 Psychology 30, no. 3 (June 1, 1996): 257–303. https://doi.org/10.1006/cogp.1996.0008. Review of how goals might be encoded in the frontal lobe Walton, Mark E., James Groves, Katie A. Jennings, Paula L. Croxson, Trevor Sharp, Matthew F. S. Rushworth, and David M. Bannerman. “Comparing the Role of the Anterior Cingulate Cortex and 6-Hydroxydopamine Nucleus Accumbens Lesions on Operant Effort-Based Decision Making.” European Journal of Neuroscience 29, no. 8 (April 1, 2009): 1678–91. https://doi.org/10.1111/j.1460-9568.2009.06726.x. Rodent study of dopamine in effort-based decisions Manohar, SG., Rebecca Dawn Finzi, Daniel Drew, and Masud Husain. “Distinct Motivational Effects of Contingent and Noncontingent Rewards.” Psychological Science 28, no. 7 (July 1, 2017): 1016–26. https://doi.org/10.1177/0956797617693326. Motivation by both guaranteed and performance-dependent rewards Aarts, Esther, Mieke van Holstein, and Roshan Cools. “Striatal Dopamine and the Interface between Motivation and Cognition.” Frontiers in Psychology 2 (July 14, 2011). https://doi.org/10.3389/fpsyg.2011.00163. Subsection on “Evidence from human studies: motivation and cognitive flexibility” Schaefer, Michael, Hans-Jochen Heinze, and Imke Galazky. “Alien Hand Syndrome: Neural Correlates of Movements without Conscious Will.” PLOS ONE 5, no. 12 (December 13, 2010): e15010. https://doi.org/10.1371/journal.pone.0015010. Precuneus in alien hand Humphreys, Glyn W., and Jane M. Riddoch. “One More Cup of Coffee for the Road: Object– action Assemblies, Response Blocking and Response Capture after Frontal Lobe Damage.” Experimental Brain Research 133, no. 1 (July 1, 2000): 81–93. https://doi.org/10.1007/s002210000403. A case of utilisation behaviour: affordance competition? Boccardi, Edoardo, Sergio Della Sala, Cristina Motto, and Hans Spinnler. “Utilisation Behaviour Consequent to Bilateral SMA Softening.” Cortex; a Journal Devoted to the Study of the Nervous System and Behavior 38, no. 3 (June 2002): 289–308. Another case of utilisation behaviour – bilateral anarchic hand? Lange, Floris P. de, Karin Roelofs, and Ivan Toni. “Increased Self-Monitoring during Imagined Movements in Conversion Paralysis.” Neuropsychologia 45, no. 9 (May 15, 2007): 2051– 58. https://doi.org/10.1016/j.neuropsychologia.2007.02.002. Motor imagery in Psychogenic paralysis Liepert, Joachim, Thomas Hassa, Oliver Tüscher, and Roger Schmidt. “Electrophysiological Correlates of Motor Conversion Disorder.” Movement Disorders 23, no. 15 (November 15, 2008): 2171–76. https://doi.org/10.1002/mds.21994. Conversion disorder alters mental imagery mechanism Kuppuswamy, Annapoorna. “The Fatigue Conundrum.” Brain 140, no. 8 (August 1, 2017): 2240–45. https://doi.org/10.1093/brain/awx153. What is fatigue? Hughes, A. M., T. Chalder, C. R. Hirsch, and R. Moss-Morris. “An Attention and Interpretation Bias for Illness-Spec ific Information in Chronic Fatigue Syndrome.” Psychological Medicine 47, no. 5 (April 2017): 853–65. https://doi.org/10.1017/S0033291716002890. Chronic fatigue and attention Anarchic hand Biran, Iftah, Tania Giovannetti, Laurel Buxbaum, and Anjan Chatterjee. “The Alien Hand Syndrome: What Makes the Alien Hand Alien?” Cognitive Neuropsychology 23, no. 4 (June 1, 2006): 563–82. https://doi.org/10.1080/02643290500180282. Behavioural findings in an anarchic hand 3 Verleger, Rolf, Ferdinand Binkofski, Monique Friedrich, Peter Sedlmeier, and Detlef Kömpf. “Anarchic-Hand Syndrome: ERP Reflections of Lost Control over the Right Hemisphere.” Brain and Cognition 77, no. 1 (October 1, 2011): 138–50. https://doi.org/10.1016/j.bandc.2011.05.004. EEG in anarchic hand Arzy, Shahar, Leila S. Overney, Theodor Landis, and Olaf Blanke. “Neural Mechanisms of Embodiment: Asomatognosia Due to Premotor Cortex Damage.” Archives of Neurology 63, no. 7 (July 1, 2006): 1022–25. https://doi.org/10.1001/archneur.63.7.1022. Mental rotation deficit in asomatagnosia Gilmore, R. L., K. M. Heilman, R. P. Schmidt, E. M. Fennell, and R. Quisling. “Anosognosia during Wada Testing.” Neurology 42, no. 4 (April 1, 1992): 925–925. https://doi.org/10.1212/WNL.42.4.925. Right hemisphere and anosognosia Split brain Puccetti,