Curriculum Vitae of Nan-Shan ZHONG Professor Director of State Key Laboratory of Respiratory Disease in Guangzhou Director of Guangzhou Institute of Respiratory Disease Professor Nanshan Zhong is a Medical Professor of Guangzhou Medical College, and a supervisor of respiratory medicine doctoral candidates. He graduated from Beijing Medical College, majoring in medical sciences. At present, he holds the posts of the Chairman of Guangzhou Association for Science & Technology, Director of Guangzhou Institute of Respiratory Diseases, First Affiliated Hospital of Guangzhou Medical College, and Director-general of China State Key Laboratory of Respiratory Diseases. Professor Zhong is also a leader and principal investigator to more than 10 major scientific projects, including the State-973, State-863, Tenth State Five-year Plan, National Nature Science Grants, and WHO/GOLD global network. He has published a great number of papers in worldwide reputed SCI journals, including those in Nature Medicine, Lancet, BMJ, Am J Respir Crit Care Med, and more than 200 papers in State-level journals. His publications have received 438 citations. Besides, he has published 16 monographs including Respiratory Medicine (National College Textbooks for Medical Postgraduates), Medicine (National textbooks), Asthma: From Basic to Clinical, etc, and has gained 9 patents. Over the past decades, Prof Zhong has been a leader scientist in promoting China’s respiratory medicine towards the forefront of international advances. He first developed and refined the definition of asymptomatic asthma, later cited by WHO, through his originally designed “simple bronchial provocation test" and epidemiological surveys. In a systemic review of etiology of chronic cough in China, he elucidated the neuroinflammatory mechanisms to gastroesophageal reflux induced cough. His methods for diaphragmatic function assessment during exercise for the first time demonstrated protein-energy malnutrition in even 60% of patients with early to middle stage COPD, which generated a correction equation of basic energy intake in this cohort. A national epidemiological study steered by him showed the unprecedented prevalence of COPD in China. His famous research found that hydrosulfuryl-containing expectorants (carbocysteine) can be effective in preventing or reducing acute exacerbation of COPD. The results of this study were published in a Lancet paper (2008), which evoked huge international repercussions and was voted as “paper of the year 2008”. He has organized and participated in the development of a number of Chinese guidelines for diagnosis and management of bronchial asthma, COPD, chronic cough, SARS, and high-pathogenic avian flu. In 2009, he successfully established an MoE-administrated Changjiang Scholarship Team. Due to his great achievements in medical practices and scientific education, Prof Zhong was also a recipient to Second and Third Prizes for National Natural Sciences, Outstanding Contribution Award, First Prize of Guangdong Science and Technology Awards, and Bethune Medal (2004). He became National May Day Labor Medalist (2003), National Moral Models (2007), European Respiratory Society Lifetime Honorary Fellow (2008), People Who Moved China 2009, Advanced Individual of National Medical Health Care System (2009), Fifth Higher School Teaching Masters Award (2009) and National Award for Achievements in Teaching (2009). He has been an Academician of Chinese Academy of Engineering since 1996, and was elected the President of Chinese Medical Association (2006-2011). Education: 1955-1960 Bachelor of Medicine, (Beijing Medical University, Beijing, China) 1979-1980 Research Fellow (Respiratory Medicine, Royal Infirmary, University of Edinburgh, Edinburgh, UK) 1980-1981 Research Fellow (Respiratory Medicine, St. Bartholomew's Hospital, University of London, London, UK) Honorary Degrees: March 2007, Honarary Degree of Doctor of Medicine ,University of Edinburgh Sept.2011, Doctor of Science, honoris causa, University of Birmingham Professional Chronology: 1960-1971 Assistant lecturer, Faculty of Radiology, Beijing Medical University 1971-1974 Intern, Department of Medicine, First Affiliated Hospital, Guangzhou Medical University 1974-1978 Resident, Department of Medicine, Guangzhou Medical University 1981-present Director, Guangzhou Institute of Respiratory Disease 1978-1983 Attending Physician, Department of Medicine, Guangzhou Medical University 1983-1986 Associate Professor, Department of Medicine, Guangzhou Medical University 1986-1996 Professor, Department of Medicine, Guangzhou Medical University 1996-present Academician, Division of Health and Medicine, Chinese Academy of Engineering 1986-1992 Dean, First Affiliate Hospital, Guangzhou Medical University 1992-2002 President, Guangzhou Medical University 2008-present Director, State Key Laboratory of Respiratory Disease in Guangzhou Professional Societies: 1982-1985 Member, Executive Committee, Chinese Medical Association 1985-1990 Member, WHO Advisory Panel on Smoking & Health 1989-2000 Member, Executive Committee, American College of Chest Physician 1989-present Fellow, American College of Chest Physician (FCCP) 1995- Executive Director, Research & Education, Asian-Pacific Society of Respirology 1994-2000 Vice-chairman, Chinese Society of Respiratory Diseases 1992- Vice-chairman, Guangdong Medical Association 1995-2010 Chairman, Guangzhou Association of Science and Technology 1993- Member, European Respiratory Society 1997- Executive member, Asian-Pacific Society of Respirology (APSR) 2000-2006 International Regent for PR China, American College of Chest Physicians 2006-2011 President, Chinese Medical Association 2001-2007 Chairman, Chinese Society of Respiratory Diseases 2005-present Fellow, Royal College of Physicians of Ireland 2011-present Fellow of Royal College of Physician (FRCP Edinburgh ) 2005-present Fellow, honoris causa, Hong Kong Academy of Medicine 2008-present Fellow, honoris causa, European Respiratory Society Editorial Activities 1996- Editor Board, Journal of Hospital Medicine 1992- Editor Board, Chinese Medical Journal (English Edition) 1993- Editor in chief, Academic Journal of Guangzhou Medical University 1996- Editor in chief, Journal of Modern Chinese Medical Bioengineering 1995- Reviewer, J Respirology 1999- Reviewer, Respiratory Medicine 1992-2000 Co-editor in chief, Chinese Journal of Tuberculosis and Respiratory Diseases 2000- Editor-in-chief, Chinese Journal of Tuberculosis and Respiratory Disease 2004-present Editor-in-chief, CHEST (authorized Chinese Edition) Awards and Prizes: 1) China Ministry of Public Health Award for Advances in Science and Technology (1985) 2) National Award for Advances in Science and Technology, China (1997) 3) Outstanding Alumnus (1997) by “Beijing Medical University” 4) Outstanding Contribution Award (2003) by “Guangdong Department of Science and Technology” 5) Ho Leung Ho Lee Foundation Prize for Scientific and Technological Advancement (2003) 6) May Day Labor Medalist (2003) 7) National Award for Outstanding Health-care Worker in Anti-SARS Campaign (2003) 8) Bethune's Prize, China (2004) 9) Chinese Doctor Prize (2003) 10) National Role Model of Labors (2005) 11) WAO Awards for Distinguished Recognition (2007) Main Contributions: 1) Defined "Asymptomatic asthma" (Latent asthma) which was quoted by the < Global Initiative of Asthma> (WHO)1st edition ,1995 (Thorax 1990; 45: 860-5 , Chest 1992; 102: 1104-9 ) 2) Chronic Obstructive Pulmonary Disease(COPD) : Prevalence in China (Am J Respir Crit Care Med. 2007; 176(8):753-760) Biomass is one of the most risk factors of COPD in women in the rural area in China (Thorax. 2007; 62(10): 889-897 Thio compound was able to prevent acute exacerbation of COPD. Efficacy was similar to inhaled corticosteroid plus long acting B2 agonnist (Lancet 2008; 371: 2013–18 Elected as "Paper of 2008" by the Lancet Editorial Board Early intervention of COPD in the community may be benificial in reducing annual FEV1 decline (BMJ. 2010 Dec 1;341:c6387.). 3) Diagnosis and management of Severe Acute Respiratory Syndrome(SARS) Firstly described the real pathogen of SARS (Coronovirus but not Chlamydia ) in the mainland of China (Lancet 2003; 362: 1353-58) Right strategy in the management of SARS(Am J Respir Crit Care Med. 2003; 168(1): 7-9 Rational use of corticosteroid in the management of severe SARS (CHEST. 2006; 129: 1441-52, Brit Med J. 2006; 333: 289-91) Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque. Nat Med. 2005 Sept;11(9):944-51. ; Antiviral Therapy. 2004; 9:365-374 4) Etiology of chronic cough in China (Chest. 2013 Mar 1;143(3):613-20.) 5) Clinical characteristics of N7N9 infection (NEJM. 2013 May 22.) Selected Publications: Books NS Zhong, Diagnosis and Classification (asthma) in Global strategy for Asthma Management and Prevention WHLBI/WHO workshop (GINA)(1995)(Chap5, pp48-61) NS Zhong, Management of Asthma in Developing Countries. In: Asthma. PJ Barnes. Lippincott Raven Publishes Phildephia (1997), pp1869-1881.(Chapl27, pp1869-1882) NS Zhong et al. An English-Chinese-Japanese Illustrative Medical Dictionary. Man Lee Bookstore Co Ltd. Hong Kong. 1985 NS Zhong et al. Updates in Modern Respiratory Disease. People’s Health Publishing House. Beijing. 1994 NS Zhong et al. Designs in Medical Studies. Zhongshan University Publishing House. Guangzhou. 2000 NS Zhong et al. A Precise Handbook for Diagnosis and Treatment of Respiratory Diseases. Medimedia Co Ltd. 2001 NS Zhong et al. Prevention