PROFILE BOOKLET Life Sciences September 2020 Oxford University Innovation Limited Buxton Court, 3 West Way Oxford OX2 0JB www.innovation.ox.ac.uk TABLE OF CONTENTS AUTOIMMUNE DISEASES ............................................................................................................................ 1 11412 Oncostatin-M: a novel therapeutic target for inflammatory bowel disease .................................. 2 11805 Anti-inflammatory drugs from bugs ............................................................................................... 3 DATA MANAGEMENT TOOLS ...................................................................................................................... 4 9663 Dynamic Consent ............................................................................................................................ 5 10332 Sortition clinical trial randomisation .............................................................................................. 6 11339 The Rare UK Disease Study platform (RUDY) .................................................................................. 7 14422 Data acquisition and management system for personalized healthcare ....................................... 8 DEVICES AND DIAGNOSTICS ........................................................................................................................ 9 706 Sulphide sensor ............................................................................................................................. 10 2476 Saliva drug testing ......................................................................................................................... 11 2718 Real word arsenic detection ......................................................................................................... 12 7895 Bacterial identification .................................................................................................................. 13 12408 Metal-free Catalysts ..................................................................................................................... 14 12729 FieldSense – Next generation tactile feedback systems ............................................................... 15 13022 Growth prediction of abdominal aortic aneurysms ...................................................................... 16 13067 A Microfluidic Sonication Device for the Production of Coated Microbubbles ............................ 17 13151 Smart mouth guard ....................................................................................................................... 18 13249 Nuclear quadrupole resonance sensors for safer wireless power ............................................... 19 13853 Mic-seq: single cells provirus monitoring to inform on HIV cure strategies ................................. 20 13953 Density-of-state based quantum sensitive sensor........................................................................ 21 14110 Fast-response sensor for oxygen detection in gases and liquids.................................................. 22 14262 Magnetic microbubble-conjugation thrombin as a novel drug delivery system .......................... 23 14654 Automated detection of bacterial growth from a photograph of a 96 well plate ........................ 24 15519 Neuromorphic technology based on new physics ........................................................................ 25 15595 Deep vein thrombosis diagnostic device ...................................................................................... 26 15648 A new treatment to predict the growth in abdominal aortic aneurysms ..................................... 27 15823 A novel algorithm for biologically inspired lighting solutions ....................................................... 28 16143/16372 Multifunctional device for focusing light through an optical component ........................ 29 16569 Rapid method for the measurement of foetal scalp blood pH ..................................................... 30 16684 A new dual-channel needle for the extraction of oocytes during the IVF process ....................... 31 GENOMICS ................................................................................................................................................ 32 10531/15179 PubMLST molecular typing database ................................................................................ 33 14061 Chromopainter – Identifying shared ancestry .............................................................................. 34 14128 IMPUTE 4: statistical analysis of genome-wide data .................................................................... 35 14253/ 15614/ 15792 DNA cloning without sequence constraints and without ‘scar’ sequences ........ 36 14526 Gap-Seq: single molecule sequencing for single-molecule phenotyping ..................................... 37 14872 Sparse decomposition of arrays (SDA) ......................................................................................... 38 Oxford University Innovation Buxton Court, 3 West Way, Botley, Oxford OX2 0JB T +44 (0)1865 280830 E [email protected] www.innovation.ox.ac.uk Company No 2199542 Registered Office: University Offices, Wellington Square, Oxford OX1 2JD VAT No 490 7988 85 15670 RELATE: estimating genome wide genealogies for thousands of whole-genome sequences ...... 39 16224 A method for genetic modification of biofilms ............................................................................. 40 16992 IMPUTE 5 ...................................................................................................................................... 41 IMAGING .................................................................................................................................................. 42 2924/6596 Targeted MRI contrast agents for detection of brain tumours and inflammation ............... 43 9030 Improved inflammation imaging .................................................................................................... 44 9564 FSL brain-mapping software ......................................................................................................... 45 11771 Improved quantification of arterial blood-flow ............................................................................ 46 11341 Smart Align: image registration software for (S)TEM images ....................................................... 47 12191 Off-resonance correction method for MR perfusion imaging and angiography .......................... 48 12409 Post-processing deblurring for medical imaging .......................................................................... 49 13299 High throughput image analysis platform for 3D cellular tissues ................................................. 50 14289 Correcting imaging artefacts due to bidirectional scanning ......................................................... 51 15151 Non-invasive PET imaging of PARP expression ............................................................................. 52 15727 Graphene based sensor system compatible with MRI and CT imaging ....................................... 53 16185 A new method for automated 3D blood vessel reconstruction .................................................. 54 METABOLIC DISEASES ............................................................................................................................... 55 8949 UKPDS Cardiovascular Risk engine – Version 3 ............................................................................. 56 9797 Glycaemic variability calculator .................................................................................................... 57 9965 Version 2 of the UKPDS OM – A type 2 diabetes outcomes model .............................................. 58 10766 iHOMA2: software for diabetes trials and research ..................................................................... 59 10804 Early gestational diabetes diagnostic ........................................................................................... 60 NEUROSCIENCE ......................................................................................................................................... 61 8818 Are you awake? Method for measuring consciousness and depth of anaesthesia ...................... 62 11128 Diagnosing neurological autoimmune disease ............................................................................. 63 15744 Targeted drug delivery to the brain for treating neurodegenerative diseases ............................ 64 16952 Amyotrophic lateral sclerosis diagnostic ...................................................................................... 65 ONCOLOGY ............................................................................................................................................... 66 4130/11532 Acute myeloid leukaemia prognostic and diagnostic screening ........................................ 67 6855 Brain tumour detection and treatment .......................................................................................... 68 9086 Novel cancer treatment to improve the efficiency of radiotherapeutic methods ......................... 69 11735 Prediction method for skin cancer development risk in renal transplant recipients ................... 70 12273 Stratification method for proximal colorectal cancer patients ...................................................