PANCREATIC ELASTASE A highly specific and convenient assay for the quantitative Monoclonal ELISA determination of Pancreatic Elastase. PANCREATIC Pancreatic Elastase by two ELASTASE monoclonal Ab ELISA methods [μg/ml] 800 Monoclonal elisa 700 R² = 0.9426 600 500 400 300 Cat. No. Description IDK ELISA 200 K6915 IDK® Pancreatic Elastase ELISA kit. 96 100 wells. 0 0 200 400 600 800 Comparison ELISA • Sample: Faeces Biohit Healthcare Ltd • Highly specific Monoclonal Ab Pioneer House | Pioneer Business Park North Road | Ellesmere Port ELISA system Cheshire CH65 1AD | UK • Range 40 - 720 µg/mL Tel. +44 (0)151 550 4 550 Fax. +44 (0)151 550 4 551 • 5 x standards, 2 x controls [email protected] • Automatable www.biohithealthcare.co.uk 7 EN2017/0 K6915 PANCREATIC ELASTASE Monoclonal ELISA IDK® Pancreatic Elastase ELISA Background Indications: Highly specific monoclonal Ab based Pancreatic elastase is an anionic endoprotease • Diagnosis/exclusion of exocrine ELISA for the determination of of the serine protease family with a molecular pancreas insufficiency in cases of pancreatic elastase in stool: weight of 26kDa. Together with other digestive o unexplained diarrhea enzymes it is synthesized as an inactive pro- o gut microbiota dysbiosis • Monoclonal test system enzyme in the acinar cells of the pancreas and is o IBS/IBD secreted into the duodenum. o steatorrhea • Short incubation: 2 x 30 min • Small sample volume: 15mg After activation, pancreatic elastase cleaves o flatulence peptides after neutral amino acids. Pancreatic o weight loss • Automatable elastase is mainly bound to bile salts during o upper abdominal pain intestinal passage and is not degraded. In o diet intolerances Includes universal extraction buffer human faeces it is 5–6 fold more concentrated than in pancreatic juice. • Monitoring of exocrine pancreas IDK Extract® enabling complete stool function in analytics from one single extract: o cystic fibrosis o diabetes mellitus o chronic pancreatitis Faecal Calprotectin Haemoglobin (FIT) alpha-1-antitrypsin Faecal Bile Acids The concentration of pancreatic elastase in faecal samples reflects the Lactoferrin secretory capacity of the pancreas. …and more. .