Curriculum Vitae NICLAS BACKSTRÖM Address Contact details Department of Evolutionary Biology E-mail: [email protected] Evolutionary Biology Centre Phone: +46(0)18-471-6415 Uppsala University Fax: +46(0)18-471-6310 Norbyvägen 18D, 752 36 Uppsala, Sweden Webpage: http://www.ieg.uu.se/evolutionary- biology/backstrom/ Education and academic appointments 2018 – Senior lecturer, (Associate Professor), Department of Evolutionary Biology, Evolutionary Biology Centre, Uppsala University. 2017 – 2018 Associate senior lecturer, (Assistant Professor), Department of Evolutionary Biology, Evolutionary Biology Centre, Uppsala University. 2014 – 2016 Assistant Professor, Department of Evolutionary Biology, Evolutionary Biology Centre, Uppsala University. Funded by the Swedish Research Council. 2011 – 2013 Repatriation research fellow, Department of Evolutionary Biology, Evolutionary Biology Centre, Uppsala University. Funded by the Swedish Research Council. 2009 - 2011 Postdoctoral research fellow, Department of Organismic and Evolutionary Biology, Museum of Comparative Zoology, Harvard University. Funded by the Swedish Research Council. Advisor: Professor Scott V. Edwards 2009 Postdoctoral research associate, Department of Evolutionary Biology, Uppsala University. Advisor: Professor Hans Ellegren 2004 - 2009 PhD in Evolutionary Genetics, Uppsala University. Advisor: Professor Hans Ellegren 2000 - 2003 Master’s Degree (MSc) in Biology, Uppsala University Competitive grants and scholarships 2019. New Frontiers in Research Fund – Exploration (NFRFE), Canada. Project Grant (ID#: NFRFE- 2018-00738). Phenotype-genotype associations for migratory behavior in insects: combining isotope geolocation and next- generation sequencing tools. Co-applicant (Main PI; Clement Bataille, University of Ottawa). USD 200,000 ≈ SEK 1,850,000 2018. Swedish Research Council FORMAS. Project Grant (ID#: 2018-01591). Loss of biodiversity through dissolution of species boundaries. Co-applicant (Main PI; Åke Brännström, Umeå University). SEK 3,000,000 I Curriculum Vitae NICLAS BACKSTRÖM 2017. Royal Swedish Academy of Science (KVA) Project Grant (ID#: BS2017-0071). International Conference on Biology of Butterflies (ICBB) 2018. SEK 15,000 2015. Science for Life Laboratory Biodiversity Program WABI support. (ID#: 201504) Leptidea genomics. Funding for a bioinformatician working part time in the group for 12 months with possible extension. 2014. Nilsson-Ehle-Foundation, Royal Physiographic Society in Lund. Butterfly biodiversity – the roles of karyotype evolution and cryptic speciation. SEK 100,000 2014. Science for Life Laboratory Biodiversity Program (ID#: 2014/R2-20). Rapid karyotype evolution and cryptic speciation underlying butterfly biodiversity. SEK 252,000 2013. Swedish Research Council (VR) Young Investigator Grant (ID#: 2013-4508). Genomic consequences of cryptic speciation and rapid karyotype evolution in Leptidea butterflies. SEK 4,380,000 2013. Royal Swedish Academy of Science (KVA) Project Grant (ID#: FOA13H-088). The genetics of reproductive isolation in an avian hybrid zone. SEK 100,000 2012. Helge Axelson Johnson's Foundation. The genetics of reproductive isolation in a chiffchaff (Phylloscopus collybita sp.) hybrid zone. SEK 45,000 2011. Foundation Lars Hiertas Memory. The genetics of reproductive isolation in chiffchaff (Phylloscopus collybita sp.). SEK 20,000 2011. Nilsson-Ehle-Foundation, Royal Physiographic Society in Lund. The genetics of reproductive isolation in a chiffchaff (Phylloscopus collybita sp.) hybrid zone. SEK 83,000 2011. Swedish Research Council (VR) Repatriation research fellowship (ID#: NT 2011-22). Quantification of alternative splicing in natural populations of birds. SEK 858,000 2011. NSFC Genetic and phenotypic differentiation in the common pheasant (Phasianus colchicus). RMB 250,000 (Co-investigator with Bei An and Lixun Zhang, Lanzhou University, China) 2011. Putnam Expedition Grant, Museum of Comparative Zoology, Harvard University. Museum collections improvement trip to Mongolia. USD 45,000 (With Scott V. Edwards (PI) and Jeremiah Trimble) 2009. Swedish Research Council (VR) Postdoctoral research fellowship (ID#: 2009-693). Evolutionary genetics of disease resistance in the house finch (Carpodacus mexicanus). SEK 1,251,600 2008. Helge Axelson Johnson's Foundation. SEK 28,000 2007. Principal's Traveling Grant from The Wallenberg Foundation. SEK 10,600 2007. Nilsson-Ehle-Foundation, Royal Physiographic Society in Lund. SEK 14,850 2007. Foundation Lars Hiertas Memory. SEK 25,000 II Curriculum Vitae NICLAS BACKSTRÖM 2007. Royal Swedish Academy of Science (KVA). Student Grant (ID#: FOA07B-163). SEK 7,000 2006. Nilsson-Ehle-Foundation, Royal Physiographic Society in Lund. SEK 19,000 Peer reviewed publications 44. Wheatcroft, D., Backström, N., Dutoit, L., McFarlane, E. S., Mugal, C., Wang, M., Ålund, M., Ellegren, H., and Qvarnström, A. 2019. RNA sequencing of two closely related songbird species and their hybrids reveals divergence in regulation of synaptotagmin 4, a singing-induced neuroplasticity gene. Nature Ecology & Evolution [Submitted] 43. Talla, V., Soler, L., Kawakami, T., Dincă, V., Vila, R., Friberg, M., Wiklund, C., and Backström, N. 2019. Dissecting the effects of natural selection and mutation on genetic diversity in three recently diverged cryptic butterfly species. Genome Biology and Evolution [In Review] 42. Mugal, C. F., Wang, M., Backström, N., Wheatcroft, D., Ålund, M., McFarlane, E. S., Xu, L., Dutoit, L., Qvarnström, A. and Ellegren, H. 2019. Gene regulatory evolution in natural flycatcher populations is highly tissue-specific with no signature of hybrid mis-expression in the testis. Genome Research [In Review] 41. Höök, L., Leal, L., Talla, V., and Backström, N. 2019. Multilayered tuning of dosage compensation and Z-chromosome masculinization in the wood white (Leptidea sinapis) butterfly. Genome Biology and Evolution [In Press] 40. Talla, V., Johansson, A., Dincă, V., Vila, R., Friberg, M., Wiklund, C., and Backström, N. 2019. Lack of parallelism: lineage specific selection drives genome differentiation in three cryptic wood white (Leptidea sp.) species. Molecular Ecology 28: 3756-3770. doi: 10.1111/mec.15188 39. Leal, L., Talla, V., Källman, T., Friberg, M., Wiklund, C., Dincă, V., Vila, R., and Backström, N. 2018. Gene expression profiling across ontogenetic stages in the wood white (Leptidea sinapis) reveals pathways linked to butterfly diapause regulation. Molecular Ecology 27: 935-948. doi: 10.1111/mec.14501 38. Talla, V., Kalsoom, F., Shipilina, D., Marova, I., and Backström, N. 2017. Heterogeneous patterns of genetic diversity and differentiation in European and Siberian chiffchaff (Phylloscopus collybita abietinus / P. tristis). G3: Genes, Genomes, Genetics 7: 3983-3998. doi: https://doi.org/10.1534/g3.117.300152 37. Talla, V., Suh, A., Kalsoom, F., Dincă, V., Vila, R., Friberg, M., Wiklund, C., and Backström, N. 2017. Rapid increase in genome size as a consequence of transposable element hyperactivity in wood-white (Leptidea) butterflies. Genome Biology and Evolution 9: 2491-2505. doi: https://doi.org/10.1093/gbe/evx163 III Curriculum Vitae NICLAS BACKSTRÖM 36. Shipilina, D., Serbyn, M., Ivanitskii, V., Marova, I. M., and Backström, N. 2017. Patterns of genetic, phenotypic and acoustic variation across a chiffchaff (Phylloscopus collybita abietinus/tristis) hybrid zone. Ecology & Evolution 7: 2169-2180. doi: 10.1002/ece3.2782 35. Knief, U., Schielzeth, H., Backström, N., Hemmrich-Stanisak, G., Wittig, M., Franke, A., Griffith, S., Ellegren, H., Kempenaers, B., and Forstmeier, W. 2017. Association mapping of morphological traits in wild and captive zebra finches: reliable within but not between populations. Molecular Ecology 26: 1285-1305. doi: 10.1111/mec.14009 34. Uebbing, S., Künstner, A., Mäkinen, H., Backström, N., Bolivar, P., Burri, R., Dutoit, L., Mugal, C. F., Nater, A., Aken, B., Flicek, P., Martin, F. J., Searle, S. M. J., and Ellegren, H. 2016 Divergence in gene expression within and between two closely related flycatcher species. Molecular Ecology 25: 2015-2028. doi: 10.1111/mec.13596 33. Dincă, V., Backström, N., Dapporto, L., Friberg, M., Garcia-Barros, E., Hebert, P. D. N., Hernandez-Roldan, J. Hornett, E., Lukhtanov, V., Marec, F., Montagud, S., Munguira, M. L., Olofsson, M., Sichova, J., Talavera, G., Vicente-Arranz, J. C., Vila, R., and Wiklund, C. 2015. DNA barcodes highlight unique research models in European butterflies. Genome: 58: e163. 32. Uebbing, S., Konzer, A., Xu, L., Backström, N., Brunström, B., Bergqvist, J., and Ellegren, H. 2015. Quantitative mass spectrometry reveals partial translational regulation for dosage compensation in chicken. Molecular Biology and Evolution 32: 2716-2725. doi: 10.1093/molbev/msv147 31. Romanov, M. N., Farré, M., Lithgow, P. E., Fowler, K. E., Skinner, B. M., O’Connor, R., Fonseka, G., Backström, N., Matsuda, Y., Nishida, C., Houde, P., Jarvis, E., Ellegren, H., Burt, D. W., Larkin, D. M., and Griffin, D. K. 2014. Reconstruction of gross avian genome structure, organization and evolution suggests that the chicken lineage most closely resembles the dinosaur avian ancestor. BMC Genomics 15: 1060. doi: 10.1186/1471-2164-15-1060 30. Zhang, Q., Hill, G. E., Edwards, S. V., and Backström, N. 2014. A house finch (Haemorhous mexicanus) spleen transcriptome reveals intra- and interspecific patterns of gene expression, alternative splicing and genetic diversity in passerines. BMC Genomics 15: 305. doi:10.1186/1471-2164-15-305 29. Backström,