Datasheet Version: 1.0.0 Revision date: 02 Nov 2020 Alpha Adducin Phospho-Thr445 (ADD1 pT445) Antibody Catalogue No.:abx326604 Alpha Adducin (ADD1) (pT445) Antibody is a Rabbit Polyclonal against Alpha Adducin (ADD1) (pT445). Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Target: Alpha Adducin Phospho-Thr445 (ADD1 pT445) Clonality: Polyclonal Target Modification: Thr445 Modification: Phosphorylation Reactivity: Human, Mouse, Rat Tested Applications: ELISA, IHC Host: Rabbit Recommended dilutions: IHC: 1/100 - 1/300, ELISA: 1/5000. Optimal dilutions/concentrations should be determined by the end user. Conjugation: Unconjugated Immunogen: Synthesized peptide derived from human Adducin α around the phosphorylation site of T445. Isotype: IgG Form: ForLiquid Reference Only Purification: Affinity Chromatography. Storage: Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. UniProt Primary AC: P35611 (UniProt, ExPASy) Q9QYC0 (UniProt, ExPASy) Gene Symbol: ADD1 GeneID: 118 v1.0.0 Abbexa Ltd, Cambridge, UK · Phone: +44 1223 755950 · Fax: +44 1223 755951 1 Abbexa LLC, Houston, TX, USA · Phone: +1 832 327 7413 www.abbexa.com · Email: [email protected] Datasheet Version: 1.0.0 Revision date: 02 Nov 2020 OMIM: 102680 NCBI Accession: NP_001110.2, NM_001119.4, [P35611-1], NP_001273574.1, NM_001286645.1, [P35611-4], NP_054908.2, NM_014189.3, [P35611-3], NP_054909.2, NM_014190.3, [P35611-2], NP_789771.1, NM_176801.2, [P35611-6], XP_005247994.1, XM_005247937.2, [P35611-4], XP_016863193.1, XM_017007704.1, [P35611-3], XP_016863195.1, XM_017007706.1, [P35611-1], XP_016863196.1, XM_017007707.1, [P35611-1], XP_016863197.1, XM_017007708.1, [P35611-4], XP_016863198.1, XM_017007709.1, [P35611-2], XP_016863199.1, XM_017007710.1, [P35611-2] HGNC: 243 Ensembl: ENSG00000087274 String: 9606.ENSP00000264758 10090.ENSMUSP00000109979 Buffer: PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Note: This product is for research use only. For Reference Only v1.0.0 Abbexa Ltd, Cambridge, UK · Phone: +44 1223 755950 · Fax: +44 1223 755951 2 Abbexa LLC, Houston, TX, USA · Phone: +1 832 327 7413 www.abbexa.com · Email: [email protected].