Biological Methylation: Fundamental Mechanisms in Human Health and Disease Hilton Florence Metropole Florence, Italy June 17 – 22, 2018 Co-organizers: Maria Elena Torres-Padilla, Ph.D. Associate Professor, Institute of Epigenetics and Stem Cells Helmholtz Zentrum München Xiaobing Shi, Ph.D. Professor, Center for Epigenetics Van Andel Research Institute Sunday, June 17 4:00-9:00pm Conference Registration 4:45-5:00pm Welcome from FASEB and the organizers Keynote address 5:00-6:00pm Kristian Helin, University of Copenhagen Histone methylation and human cancer 6:00-7:00pm Welcome reception 7:00-8:00pm DINNER Monday, June 18 7:30-9:00am BREAKFAST 7:30-12:00pm Conference Registration Session 1: Methylation and chromatin regulation 9:00-12:00pm Chair: Scott Rothbart, Van Andel Research Institute 9:00-9:30am Thomas Jenuwein, Max Planck Institute of Immunology and Epigenetics 9:30-10:00am Robert Schneider, Institute of Functional Epigenetics, Munich 10:00-10:30am Brian Strahl, University of North Carolina at Chapel Hill 10:30-11:00am Coffee break and GROUP PHOTO 11:00-11:30am Jerry Workman, Stowers Institute 11:30-11:45am Eric Selker, University of Pennsylvania 11:45-12:00pm Rochelle Tiedemann, Van Andel Research Institute 12:00-1:00pm LUNCH and Meet the Experts 1:00-2:00pm Career Development Workshops 2:00-4:00pm FREE AFTERNOON Keynote address 4:00-5:00pm Tom Muir, Princeton University Protein methylation: chemistry and beyond Session 2: Quantitative approaches to protein methylation 5:00-6:30pm Chair: Xiaobing Shi, Van Andel Research Institute 5:00-5:30pm Minkui Luo, Memorial Sloan Kettering Cancer Center 5:30-6:00pm Axel Imhof, Ludwig Maximilian University of Munich 6:00-6:15pm Scott Rothbart, Van Andel Research Institute 6:15-6:30pm George Zheng, Emory University 6:30-6:45pm Joshua Hamey, The University of New South Wales 7:00-8:00pm DINNER 5:00-8:00pm Conference Registration 8:00-10:00pm POSTER SESSION 1 Tuesday, June 19 7:30-9:00am BREAKFAST Session 3: Protein methylation in development and disease 9:00-12:15pm Chair: Maria Elena Torres-Padilla, Helmholtz Zentrum Muenchen 9:00-9:30am Jürg Müller, Max Planck Institute of Biochemistry 9:30-10:00am Jonathan Whetstine, Harvard Medical School 10:00-10:15am Clare Davies, University of Birmingham 10:15-10:30am Jian Jin, Icahn School of Medicine at Mount Sinai 10:30-10:45am Coffee break 10:45-11:15am Rob Klose, University of Oxford 11:15-11:45am Or Gozani, Stanford University 11:45-12:00pm Pål Falnes, University of Oslo 12:00-12:15pm Jian Xu, University of Southern California 12:15-1:15pm LUNCH 1:15-5:00pm FREE AFTERNOON Session 4: Arginine methylation: players and mechanisms 5:00-7:00pm Chair: Ernesto Guccione, Institute of Molecular and Cell Biology 5:00-5:30pm Mark Bedford, MD Anderson Cancer Center 5:30-6:00pm Stéphane Richard, McGill University 6:00-6:30pm Ernesto Guccione, Institute of Molecular and Cell Biology - A Star 6:30-6:45pm Humaira Gowher, Purdue University 6:45-7:00pm Kanishk Jain, University of California, Los Angeles 7:00-8:00pm DINNER 8:00-10:00pm POSTER SESSION 2 Wednesday, June 20 7:30-9:00am BREAKFAST Session 5: Modifications of nucleic acids 9:00-12:15pm Chair: Taiping Chen, MD Anderson Cancer Center 9:00-9:30am Peter Jones, Van Andel Research Institute 9:30-10:00am Anjana Rao, La Jolla Institute for Allergy and Immunology 10:00-10:30am Steve Jacobsen, University of California, Los Angeles 10:30-10:45am Coffee break 10:45-11:15am Andrew Xiao, Yale University 11:15-11:45am Mark Dawson, Peter MacCallum Cancer Centre 11:45-12:00pm Greg Wang, University of North Carolina at Chapel Hill 12:00-12:15pm Roopa Thapar, MD Anderson Cancer Center 12:15-1:15pm LUNCH 1:15-7:00pm FREE AFTERNOON 7:00-8:00pm DINNER TECHNOLOGY WORKSHOP SESSION 8:00-9:30pm Chair: Mark Bedford, MD Anderson Cancer Center 8:00-8:15pm Spencer Haws, UW-Madison 8:15-8:30pm Olena Barbash, GSK 8:30-8:40pm Sriharsa Pradhan, NEB 8:45-9:00pm Shikhar Sharma, Pfizer 9:00-9:15pm Said Goueli, Promega 9:15-9:30pm Johannes Bacher, University of Freiburg Thursday, June 21 7:30-9:00am BREAKFAST Session 6: Modulating methylation in disease and aging 9:00-12:15pm Chair: Yali Dou, University of Michigan 9:00-9:30am Yang Shi, Harvard Medical School 9:30-10:00am Taiping Chen, MD Anderson Cancer Center 10:00-10:15am Ryan Kruger, GSK 10:15-10:30am Erin Green, University of Maryland 10:30-10:45am Coffee break 10:45-11:15am Yali Dou, University of Michigan 11:15-11:45am Panagis Filippakopoulos, Ludwig Institute for Cancer 11:45-12:00pm Qin Yan, Yale University 12:00-12:15pm Dan Levy, Ben-Gurion University 12:15-1:15pm LUNCH 1:15-4:30pm FREE AFTERNOON Session 7: Structural insights to protein methylation 4:30-6:30pm Chair: Robert Schneider, Helmholtz Centre Munich 4:30-5:00pm Xiaodong Cheng, MD Anderson Cancer Center 5:00-5:30pm Cheryl Arrowsmith, Structural Genomics Consortium 5:30-6:00pm Tatiana Kutateladze, University of Colorado 6:00-6:30pm Rui-Ming Xu, Chinese Academy of Sciences 7:00-8:00pm DINNER Session 8: Methylation and Therapeutics 8:00-9:30pm Chair: Qin Yan, Yale University 8:00-8:30pm Karsten Rippe, Universität Heidelberg 8:30-8:45pm Anita Raposo, Western Sydney University 8:45-9:00pm Evelyne Lima Fernandes, University of Toronto 9:00-9:15pm Shatha AbuHammad, Peter MacCallum Cancer Centre 9:15-9:30pm Business meeting Friday, June 22 7:30-9:00am BREAKFAST Session 9: Methylation dynamics and transcription control 9:00-12:15pm Chair: Fei Lan, Fudan University 9:00-9:30am Kai Ge, NIH 9:30-9:45am Christine Schaner Tooley, SUNY Buffalo 9:45-10:00am Nicolas Reynoird, Grenoble-Alpes University 10:00-10:15am Donghang Cheng, MD Anderson Cancer Center 10:15-10:30am Tiziana Bonaldi, European Institute of Oncology 10:30-10:45am Coffee break 10:45-11:15am Anja Groth, University of Copenhagen 11:15-11:30am Coralie Poulard, University of Southern California 11:30-11:45am Fei Lan, Fudan University 11:45-12:00pm Closing Remarks 12:00-1pm LUNCH and DEPART END OF CONFERENCE For additional information contact: FASEB Science Research Conferences 9650 Rockville Pike, Bethesda, MD 20814 www.faseb.org/src .