CHOLANGIOCARCINOMA TERMINOLOGY CHART CANCERS THAT AFFECT THE GI (Gastrointestinal) Cancers DIGESTIVE SYSTEM { Gastric Small Biliary Primary Liver Cancer Large TYPES OF GI CANCERS Esophageal Pancreas Anal { (Stomach) Intestine Tract or Hepatocellular (HCC) Intestine Colon Rectal Biliary Tract Cancers The biliary tract includes the gallbladder and bile ducts inside and outside the liver TYPES OF Primary Liver Cancer *Combined Hepatocellular Cholangiocarcinoma HEPATOBILIARY CANCERS (HCC) and Intrahepatic Gall Bladder (CCA) PRIMARY TUMORS ORIGINATING or Hepatocellular (HCC) Cholangiocarcinoma (CCA) ( FROM THE LIVER AND BILE DUCTS ) { Some intrahepatic cholangiocarcinoma tumors have microscopic features of both hepatocellular carcinoma and cholangiocarcinoma and are considered “combined” or “mixed” tumors. THREE SUBTYPES OF Perihilar CHOLANGIOCARCINOMA Intrahepatic Distal BASED ON TUMOR LOCATION (Klatskin Tumor) { Intrahepatic CCA occurs inside the liver where Perihilar CCA occurs outside the liver after the right Distal CCA occurs outside the liver after the right cancer develops in the hepatic bile ducts or the and left hepatic bile ducts have joined to form the and left hepatic bile ducts have joined to form the smaller intrahepatic biliary ducts. In some cases, common bile duct. This type of cancer is found common bile duct. This type of cancer is found patients express a combined diagnosis.* where the common bile duct has not yet reached where the common bile duct passes through the the pancreas or the small intestine. pancreas and into the small intestine. Extrahepatic or Bile Duct Cancer Develops inside the bile ducts but outside the liver Copyright 2017 The Choloangiocarcinoma Foundation - R. Kate (Katie) Kelley, MD - Ghassan K. Abou-Alfa, MD, MBA.