Anti-DLK1 monoclonal antibody, clone NN0625- 0E9 (CABT-31393MH) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Product Overview Mouse monoclonal antibody to Human DLK1. Antigen Description This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9. Immunogen Recombinant Human DLK protein. Isotype IgG2b Source/Host Mouse Species Reactivity Human Clone NN0625-0E9 Purification Protein G purified Conjugate Unconjugated Applications FC, ICC/IF, IHC-P, WB Sequence Similarities Contains 6 EGF-like domains. Format Liquid Concentration 0.500 mg/ml Size 50 μg Buffer Preservative: NoneConstituents: PBS Preservative None Storage Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved cycles. GENE INFORMATION Gene Name DLK1 delta-like 1 homolog (Drosophila) [ Homo sapiens ] Official Symbol DLK1 Synonyms DLK1; delta-like 1 homolog (Drosophila); delta like homolog (Drosophila); protein delta homolog 1; FA1; pG2; Pref 1; ZOG; Adipocyte differentiation inhibitor protein; Brevideltin; Delta like 1 homolog; Delta like homolog; Delta like protein; DLK 1; DLK; DLK-1; Dlk1; DLK1_HUMAN; FA 1; FA1; Fetal antigen 1; pG2; Preadipocyte factor 1; Pref 1; Pref; Pref1; Protein delta homolog 1; Secredeltin; ZOG; DLK-1; secredeltin; fetal antigen 1; OTTHUMP00000246567; OTTHUMP00000246568; preadipocyte factor 1; DLK; PREF1; Pref-1; Entrez Gene ID 8788 Protein Refseq NP_003827 UniProt ID A0A024R6L1 Chromosome Location 14q32 Pathway Adipogenesis, organism-specific biosystem; FOXA2 and FOXA3 transcription factor networks, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem; Function molecular_function; 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved.