Pathology User Guide

<ul style="display: flex;"><li style="flex:1">Whittington Health </li><li style="flex:1">Version: 2021.1 </li><li style="flex:1">MB 129 </li></ul>Microbiology Department Print Date: 27 April 2021 Author: Service Managers Authorised by: DW Page 1 of 189 Issue Date: 26 April 2021 PATHOLOGY USER GUIDE Version 2021.1 Document Number : MB 129 Approved By: David Whittington 1 The master document is controlled electronically. Printed copies of this document are not controlled. Document users are responsible for ensuring printed copies are valid prior to use. <ul style="display: flex;"><li style="flex:1">Whittington Health </li><li style="flex:1">Version: 2021.1 </li><li style="flex:1">MB 129 </li></ul>Microbiology Department Print Date: 27 April 2021 Author: Service Managers Authorised by: DW Page 2 of 189 Issue Date: 26 April 2021 CONTENTS <a href="#5_0">GENERAL INFORMATION..................................................................................................................... 5 </a><a href="#5_1">INTRODUCTION................................................................................................................................. 5 </a><a href="#5_2">ADDRES</a><a href="#5_2">S</a><a href="#5_2">.</a><a href="#5_2">.......................................................................................................................................... 5 </a><a href="#5_3">LOCATIO</a><a href="#5_3">N</a><a href="#5_3">.</a><a href="#5_3">......................................................................................................................................... 5 </a><a href="#5_4">GENERAL ENQUIRIES ...................................................................................................................... 5 </a><a href="#6_0">OPERATIONAL PATHOLOGY LABORATORY MANAGER............................................................... 6 </a><a href="#6_1">SERVICE AVAILABILIT</a><a href="#6_1">Y</a><a href="#6_1">.</a><a href="#6_1">................................................................................................................... 6 </a><a href="#6_2">PHLEBOTOMY SERVICE................................................................................................................... 6 </a><a href="#7_0">TESTS </a><a href="#7_0">AND </a><a href="#7_0">SAMPLE</a><a href="#7_0">S</a><a href="#7_0">.</a><a href="#7_0">....................................................................................................................... 7 </a><a href="#7_1">PERSONS MAKING REQUEST</a><a href="#7_1">S</a><a href="#7_1">.</a><a href="#7_1">...................................................................................................... 7 </a><a href="#8_0">CONSENT........................................................................................................................................... 8 </a><a href="#8_1">REQUEST FORM</a><a href="#8_1">S</a><a href="#8_1">.</a><a href="#8_1">............................................................................................................................ 8 </a><a href="#8_2">General</a><a href="#8_2">……………………………………………………………………………………………………..</a><a href="#8_2">8 </a><a href="#8_3">Completion of the Request For</a><a href="#8_3">m</a><a href="#8_3">.</a><a href="#8_3">................................................................................................... 8 </a> <a href="#9_0">SAMPLE LABELLING ......................................................................................................................... 9 </a><a href="#9_1">General</a><a href="#9_1">……………………………………………………………………………………………………</a><a href="#9_1">9 </a><a href="#10_0">Blood Transfusio</a><a href="#10_0">n</a><a href="#10_0">.</a><a href="#10_0">........................................................................................................................ 10 </a> <a href="#10_1">SPECIMEN TRANSPORT TO THE LABORATOR</a><a href="#10_1">Y</a><a href="#10_1">.</a><a href="#10_1">........................................................................ 10 </a> <a href="#10_2">Packaging and Sending Samples to the Laboratory .................................................................... 10 </a><a href="#10_3">Ward and Clinic Collection Times................................................................................................. 10 </a><a href="#11_0">Pneumatic Air Tube System ......................................................................................................... 11 </a><a href="#12_0">Urgent Requests during Routine Working Hours ......................................................................... 12 </a><a href="#12_1">Unstable Analyte</a><a href="#12_1">s</a><a href="#12_1">.</a><a href="#12_1">........................................................................................................................ 12 </a><a href="#12_2">Out-of Hours Specimen Transport................................................................................................ 12 </a><a href="#12_3">GP Transport ................................................................................................................................ 12 </a> <a href="#13_0">RESULTS AVAILABILITY ................................................................................................................. 13 </a><a href="#13_1">LABORATORY COMPUTER ............................................................................................................ 13 </a><a href="#13_2">RESULTS INTERPRETATION ......................................................................................................... 13 </a><a href="#14_0">REFERENCE RANGE</a><a href="#14_0">S</a><a href="#14_0">.</a><a href="#14_0">................................................................................................................... 14 </a><a href="#14_1">MEASUREMENT UNCERTAINTY.................................................................................................... 14 </a><a href="#14_2">DOWNTIME ...................................................................................................................................... 14 </a><a href="#14_3">COMPLAINT</a><a href="#14_3">S</a><a href="#14_3">.</a><a href="#14_3">.................................................................................................................................. 14 </a> <a href="#14_4">Complaints by Requesters of Tests.............................................................................................. 14 </a><a href="#15_0">Complaints by Patients ................................................................................................................. 15 </a> <a href="#15_1">PATIENT CONFIDENTIALITY .......................................................................................................... 15 </a><a href="#16_0">BLOOD SCIENCES .............................................................................................................................. 16 </a><a href="#16_1">BIOCHEMISTR</a><a href="#16_1">Y</a><a href="#16_1">.</a><a href="#16_1">.............................................................................................................................. 16 </a> <a href="#16_2">TELEPHONE NUMBER</a><a href="#16_2">S</a><a href="#16_2">.</a><a href="#16_2">............................................................................................................ 16 </a><a href="#16_3">ENQUIRIES and CLINICAL ADVICE ........................................................................................... 16 </a><a href="#16_4">URGENT REQUEST</a><a href="#16_4">S</a><a href="#16_4">.</a><a href="#16_4">................................................................................................................. 16 </a><a href="#16_5">REFERRED TESTS...................................................................................................................... 16 </a><a href="#17_0">ON-CALL SERVICE...................................................................................................................... 17 </a><a href="#17_1">RESULTS ..................................................................................................................................... 17 </a> <a href="#17_2">A</a><a href="#17_2">LERT </a><a href="#17_2">/ C</a><a href="#17_2">RITICAL </a><a href="#17_2">A</a><a href="#17_2">CTION </a><a href="#17_2">L</a><a href="#17_2">IMITS </a><a href="#17_2">........................................................................................................ 17 </a> <a href="#18_0">TOXICOLOGY .............................................................................................................................. 18 </a><a href="#19_0">THERAPEUTIC DRUGS .............................................................................................................. 19 </a><a href="#19_1">CARDIAC MARKER</a><a href="#19_1">S</a><a href="#19_1">.</a><a href="#19_1">.................................................................................................................. 19 </a><a href="#19_2">LIVER FUNCTION TESTS ........................................................................................................... 19 </a>2 The master document is controlled electronically. Printed copies of this document are not controlled. Document users are responsible for ensuring printed copies are valid prior to use. <ul style="display: flex;"><li style="flex:1">Whittington Health </li><li style="flex:1">Version: 2021.1 </li><li style="flex:1">MB 129 </li></ul>Microbiology Department Print Date: 27 April 2021 Author: Service Managers Authorised by: DW Page 3 of 189 Issue Date: 26 April 2021 <a href="#19_3">THYROID FUNCTION TESTS ..................................................................................................... 19 </a><a href="#19_4">LIPIDS </a><a href="#19_4">……………………………………………………………………………………………………</a><a href="#19_4">19 </a><a href="#19_5">REJECTED REQUEST</a><a href="#19_5">S</a><a href="#19_5">.............................................................................................................. 19 </a><a href="#20_0">BIOCHEMISTRY TIME LIMITS FOR REQUESTING ADDITIONAL TESTS ............................... 20 </a><a href="#0_0">ARTEFACTS................................................................................................................................. 22 </a><a href="#0_1">FORMULA</a><a href="#0_1">E</a><a href="#0_1">.</a><a href="#0_1">................................................................................................................................. 23 </a><a href="#0_2">BIOCHEMISTRY TEST GUIDE.................................................................................................... 23 </a><a href="#0_3">BIOCHEMISTRY DEPARTMENT REFERENCE LABORATORIE</a><a href="#0_3">S</a><a href="#0_3">.</a><a href="#0_3">........................................... 47 </a> <a href="#0_4">HAEMATOLOGY .............................................................................................................................. 48 </a> <a href="#0_5">TELEPHONE NUMBER</a><a href="#0_5">S</a><a href="#0_5">.</a><a href="#0_5">............................................................................................................ 48 </a><a href="#0_6">URGENT REQUEST</a><a href="#0_6">S</a><a href="#0_6">.</a><a href="#0_6">................................................................................................................. 48 </a><a href="#0_7">ON-CALL SERVICE...................................................................................................................... 48 </a><a href="#0_8">RESULTS ..................................................................................................................................... 49 </a><a href="#0_9">HAEMOGLOBINOPATHY SERVICE ........................................................................................... 49 </a><a href="#0_10">TOP TEN HAEMATOLOGICAL INVESTIGATIONS .................................................................... 49 </a><a href="#0_11">HAEMATOLOGY TIME LIMITS FOR REQUESTING ADD ON TESTS ...................................... 52 </a><a href="#0_12">FACTORS THAT CAN AFFECT SAMPLE INTEGRITY............................................................... 53 </a><a href="#0_13">HAEMATOLOGY TEST GUIDE ................................................................................................... 53 </a><a href="#0_3">TEST REPERTOIRE .................................................................................................................... 54 </a><a href="#0_14">REFERRAL TESTS ...................................................................................................................... 61 </a> <a href="#0_4">BLOOD TRANSFUSIO</a><a href="#0_4">N</a><a href="#0_4">.</a><a href="#0_4">.................................................................................................................. 63 </a> <a href="#0_15">SPECIMEN REQUIREMENT</a><a href="#0_15">S</a><a href="#0_15">.</a><a href="#0_15">.................................................................................................... 63 </a><a href="#0_16">IMPROVING THE SAFETY OF BLOOD TRANSFUSION: ABO CONFIRMATORY TESTING... 63 </a><a href="#0_3">TEST REPERTOIRE .................................................................................................................... 64 </a><a href="#0_17">TURNAROUND TIMES ................................................................................................................ 67 </a><a href="#0_18">REFERRAL TESTS ...................................................................................................................... 68 </a><a href="#0_19">MICROBIOLOG</a><a href="#0_19">Y</a><a href="#0_19">.</a><a href="#0_19">................................................................................................................................. 69 </a><a href="#0_20">INTRODUCTION............................................................................................................................... 69 </a><a href="#0_21">LABORATORY HOUR</a><a href="#0_21">S</a><a href="#0_21">.</a><a href="#0_21">................................................................................................................... 69 </a><a href="#0_22">AVAILABILITY OF CLINICAL ADVICE ............................................................................................. 69 </a><a href="#0_23">ON-CALL SERVIC</a><a href="#0_23">E</a><a href="#0_23">.</a><a href="#0_23">......................................................................................................................... 69 </a><a href="#0_24">TELEPHONE NUMBERS.................................................................................................................. 70 </a><a href="#0_25">USE OF THE LABORATORY............................................................................................................ 70 </a> <a href="#0_26">Requesting.................................................................................................................................... 70 </a><a href="#0_24">Requesting Additional Test</a><a href="#0_24">s</a><a href="#0_24">.</a><a href="#0_24">........................................................................................................ 71 </a><a href="#0_18">Specimen Containers </a><a href="#0_18">................................................................................................................. 72 </a> <a href="#0_27">TURNAROUND TIME</a><a href="#0_27">S</a><a href="#0_27">.</a><a href="#0_27">.................................................................................................................... 73 </a><a href="#0_28">BACTERIOLOG</a><a href="#0_28">Y</a><a href="#0_28">.</a><a href="#0_28">............................................................................................................................. 73 </a> <a href="#0_29">GENERAL REPORTING GUIDELINES ....................................................................................... 73 </a><a href="#0_30">1. </a><a href="#0_18">2. </a><a href="#0_31">2.4 </a><a href="#0_32">2.5 </a><a href="#0_33">3. </a> <a href="#0_30">Urinary Tract Investigatio</a><a href="#0_30">n</a><a href="#0_30">.</a><a href="#0_30">.............................................................................................. 74 </a><a href="#0_18">Gastrointestinal Disease Investigation ............................................................................ 77 </a><a href="#0_31">Specimen collection for Helicobacter Antigen testing ..................................................... 79 </a><a href="#0_32">Specimen collection for Norovirus Investigatio</a><a href="#0_32">n</a><a href="#0_32">.</a><a href="#0_32">............................................................. 80 </a><a href="#0_33">Sterile Body Fluid Investigation ....................................................................................... 80 </a><ul style="display: flex;"><li style="flex:1"><a href="#0_18">Superficial/Non-Superficial Body Sites/Tissues/Abscess/Other Body fluids/Tips </a></li><li style="flex:1"><a href="#0_18">4</a></li></ul><a href="#0_18">Investigation ................................................................................................................... 83 </a> <a href="#0_34">Abscess </a><a href="#0_34">....................................................................................................................................... 83 </a><a href="#0_35">Ear </a><a href="#0_36">Eye </a><a href="#0_37">5</a><a href="#0_38">6</a><a href="#0_39">7</a><a href="#0_40">8</a><a href="#0_41">9</a><a href="#0_42">10 </a><a href="#0_35">……………………………………………………………………………………………………</a><a href="#0_35">83 </a><a href="#0_36">……………………………………………………………………………………………………</a><a href="#0_36">84 </a><a href="#0_37">Throat swabs</a><a href="#0_37">.................................................................................................................. 84 </a><a href="#0_38">MRSA SCREENING INVESTIGATIO</a><a href="#0_38">N</a><a href="#0_38">.</a><a href="#0_38">.......................................................................... 84 </a><a href="#0_39">Miscellaneous investigatio</a><a href="#0_39">n</a><a href="#0_39">.</a><a href="#0_39">............................................................................................ 85 </a><a href="#0_40">Blood Culture Investigatio</a><a href="#0_40">n</a><a href="#0_40">.</a><a href="#0_40">............................................................................................. 86 </a><a href="#0_41">Respiratory Sample Investigatio</a><a href="#0_41">n</a><a href="#0_41">.</a><a href="#0_41">................................................................................... 89 </a><a href="#0_42">Skin, Hair and Nails Investigation for Dermatophyt</a><a href="#0_42">e</a><a href="#0_42">.</a><a href="#0_42">...................................................... 93 </a>3 The master document is controlled electronically. Printed copies of this document are not controlled. Document users are responsible for ensuring printed copies are valid prior to use. <ul style="display: flex;"><li style="flex:1">Whittington Health </li><li style="flex:1">Version: 2021.1 </li><li style="flex:1">MB 129 </li></ul>Microbiology Department Print Date: 27 April 2021 Author: Service Managers Authorised by: DW Page 4 of 189 Issue Date: 26 April 2021 <ul style="display: flex;"><li style="flex:1"><a href="#0_43">11 </a></li><li style="flex:1"><a href="#0_43">INVESTIGATION OF GENITAL INFECTIONS................................................................ 94 </a></li></ul><a href="#0_44">12 </a><a href="#0_44">SEMEN ANALYSI</a><a href="#0_44">S</a><a href="#0_44">......................................................................................................... 97 </a> <a href="#0_45">VIRAL ISOLATION </a><a href="#0_45">........................................................................................................................... 99 </a><a href="#0_46">SEROLOGY/IMMUNOLOGY</a><a href="#0_46">.......................................................................................................... 100 </a><a href="#0_47">T</a><a href="#0_47">AKING THE </a><a href="#0_47">S</a><a href="#0_47">AMPL</a><a href="#0_47">E</a><a href="#0_47">......................................................................................................................... 129 </a> <a href="#0_48">THERAPEUTIC DRUG MONITORING</a><a href="#0_48">.......................................................... 139 </a><a href="#0_49">HISTO/CYTOPATHOLOGY................................................................................................................ 140 </a><a href="#0_50">TELEPHONE NUMBERS................................................................................................................ 140 </a><a href="#0_51">GENERAL INFORMATIO</a><a href="#0_51">N</a><a href="#0_51">.</a><a href="#0_51">............................................................................................................ 140 </a><a href="#0_4">HISTOPATHOLOGY INVESTIGATIONS........................................................................................ 141 </a> <a href="#0_52">Sending the specimen ................................................................................................................ 141 </a><a href="#0_53">Availability of formalin containers ............................................................................................... 141 </a><a href="#0_54">Request Forms ........................................................................................................................... 141 </a><a href="#0_55">When will the result be available? .............................................................................................. 141 </a><a href="#0_56">Urgent report</a><a href="#0_56">s</a><a href="#0_56">........................................................................................................................... 142 </a><a href="#0_57">Frozen sections........................................................................................................................... 142 </a><a href="#0_58">Factors known to affect the interpretation of histology specimen</a><a href="#0_58">s</a><a href="#0_58">.</a><a href="#0_58">............................................ 142 </a><a href="#0_59">How do I get histology results</a><a href="#0_59">?</a><a href="#0_59">.</a><a href="#0_59">.................................................................................................. 143 </a><a href="#0_60">POST-MORTEM EXAMINATIONS </a><a href="#0_60">............................................................................................ 143 </a> <a href="#0_61">CYTOLOGY INVESTIGATIONS</a><a href="#0_61">..................................................................................................... 143 </a> <a href="#0_62">DIAGNOSTIC (NON-GYNAE) CYTOLOG</a><a href="#0_62">Y</a><a href="#0_62">.</a><a href="#0_62">.............................................................................. 144 </a>

Pathology User Guide

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