Nck Beta (NCK2) Rabbit Polyclonal Antibody – TA354479 | Origene

Nck Beta (NCK2) Rabbit Polyclonal Antibody – TA354479 | Origene

OriGene Technologies, Inc. 9620 Medical Center Drive, Ste 200 Rockville, MD 20850, US Phone: +1-888-267-4436 [email protected] EU: [email protected] CN: [email protected] Product datasheet for TA354479 Nck beta (NCK2) Rabbit Polyclonal Antibody Product data: Product Type: Primary Antibodies Applications: IHC, WB Recommended Dilution: WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml Reactivity: Human Host: Rabbit Isotype: IgG Clonality: Polyclonal Immunogen: A synthetic peptide corresponding to the C-terminus of human NCK2 protein. Formulation: This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer. Purification: The Rabbit IgG is purified by Epitope Affinity Purification Conjugation: Unconjugated Storage: Store at -20°C as received. Stability: Stable for 12 months from date of receipt. Predicted Protein Size: 45 kDa Gene Name: NCK adaptor protein 2 Database Link: NP_001004720 Entrez Gene 8440 Human O43639 Background: The NCK family of SH2/SH3 adaptor proteins consists of two members, NCK1 and NCK2, which couple tyrosine kinase signaling, including the EGF and PDGF receptor-pathways, to downstream signaling proteins. The NCK2 protein binds human PDGFR-b (Tyr-1009); overexpression of NCK2 inhibits PDGF-induced membrane ruffling and lamellipod formation. Synonyms: GRB4; NCKbeta Protein Families: Druggable Genome Protein Pathways: Axon guidance, ErbB signaling pathway, Pathogenic Escherichia coli infection, T cell receptor signaling pathway This product is to be used for laboratory only. Not for diagnostic or therapeutic use. View online » ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 1 / 2 Nck beta (NCK2) Rabbit Polyclonal Antibody – TA354479 Product images: WB: The cell lysate derived from MCF-7 was immunoblotted by the Rabbit anti-NCK2 antibody at 1:500. An immunoreactive band is observed at~45 kDa. IHC: Human breast cancer stained with Rabbit anti-NCK2 antibody at 1:50 for 30 min, RT. (Staining of formalinfixed tissues requires boiling tissue section in 10 mM Citrate Buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 2 / 2.

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