JOURNAL JOURNAL OF OPIOID MANAGEMENT Journal of Opioid ManagementTM A medical journal for proper and adequate use Volume 1, Number 3 JULY/AUGUST 2005 ISSN 1551-7489 n EDITORIAL n ORIGINAL ARTICLES Cotton candy . 119 Opiate replacement therapy at time of release from Robert E. Enck, MD incarceration: Project MOD, a pilot program. 147 Michelle McKenzie, MPH n OPIOID NEWS AND EVENTS Grace Macalino, PhD News briefs . 120 Clair McClung, BS Calendar . 122 David C. Shield, BS Josiah D. Rich, MD, MPH n GUEST EDITORIAL The opioid bowel syndrome: A review of In pain or drug-seeking? Resident continuity clinic, pathophysiology and treatment. 153 chronic nonmalignant pain, and addiction . 123 Mellar P. Davis, MD, FCCP Michael Weaver, MD No potentiation of fentanyl by use of transdermal buprenorphine in patients undergoing fast-track n LEGAL PERSPECTIVE anesthesia for open-heart surgery . 162 JULY/AUGUST 2005 Taking back your turf: Understanding the role Enno Freye, MD, PhD of law in medical decision making in opioid Erhard Hartung, MD management (Part I—Overview) . 125 Joseph Victor Levy, PhD Jennifer Bolen, JD n BOOK REVIEW n PHARMACY PERSPECTIVE Novel Aspects of Pain Management: Tramadol: Does it have a role in cancer pain Opioids and Beyond, . 168 management? . 131 Edited by Jana Sawynok and Alan Cowan Eric E. Prommer, MD Reviewed by Robert L. Barkin, PharmD, MBA, The metamorphosis of hydromorphone . 139 FCP, DAPPM Gary M. Reisfield, MD George R. Wilson, MD VOL. 1, NO. 3: 113-168 Journal of Opioid ManagementTM A medical journal for proper and adequate use 470 Boston Post Road • Weston, MA 02493 781-899-2702 • Fax: 781-899-4900 E-mail: [email protected] Journal of Opioid ManagementTM A medical journal for proper and adequate use Published bimonthly by Prime National Publishing Corporation 470 Boston Post Rd., Weston, MA 02493 • 781-899-2702, Fax: 781-899-4900 www.opioidmanagement.com E-mail: [email protected] President Publisher, Vice President Editor-in-Chief Executive Managing Editor Eileen F. DeVito Advertising Manager Robert E. Enck, MD Donna Vaillancourt Richard A. DeVito, Sr. [email protected] [email protected] Managing Editor Acquisitions Editor Staff Editor VP Sales & Operations Christie Rears Christopher V. Rowland, Jr., MD Sarah Hage Richard A. 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Multiple reprints of mater- ial published in Journal of Opioid Management can be obtained by filling out the reprint order form in the publication or by calling 781-899-2702. Trademarks and Copyrights Journal of Opioid Management is a trademark of Prime National Publishing Corp. All materials are ©2005 by Prime National Publishing Corp. All rights reserved. Postal Information Postmaster: Send address changes and form 3579 to: Journal of Opioid Management, 470 Boston Post Road, Weston, MA 02493. Disclaimer: The opinions expressed in Journal of Opioid Management are those of the authors. The authors, editors, and publishers make every effort that no inaccurate or misleading data, opinion, or statement is published in this journal and that drug names, dosages, and recommenda- tions are accurate. However, the publisher and editors accept no liability whatsoever for the consequences of any inaccurate or misleading data, opinion, or statement. Copyright 2005. Quotation is not permitted except as above. Duplicating an entire issue for sharing with others, by any means, is illegal. Photocopying of individual items for internal use is permitted for registrants with the Copyright Clearance Center, 222 Rosewood Drive, Danvers, MA 01923. For details, call 978-750-8400 or visit www.copyright.com. 12576 5/23/05 Rev. B Journal of Opioid ManagementTM A medical journal for proper and adequate use Editor-in-Chief, Robert E. Enck, MD Professor of Medicine, Assistant Division Chief for Clinical Activities, Division of Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania. Editorial Review Board Linda Gibbs Alley, PhD, RN Asokumar Buvanendran, MD Erin A. Egan, MD, JD Epidemiologist, Cancer Surveillance Department of Anesthe siology, Clinical Instructor, Neiswanger Institute Branch, Division of Cancer Prevention Rush University Medical Center, for Bioethics and Health Policy, and Control, Centers for Disease Chicago, Illinois. Loyola University Medical Center, Control and Prevention, Maywood, Illinois. Atlanta, Georgia. Guy A. Caldwell, PhD Assistant Professor of Biological Robert E. Enck, MD Lainie Andrew, PhD, MA Sci ences, The University of Alabama, Professor of Medicine, Assistant Division Pain Psychologist, Craniofacial Pain Tuscaloosa, Alabama. Chief for Clinical Ac tivities, Division of Med - Center, and Clinical Assistant i cal Oncology Thomas Jef ferson University, Professor, Tufts Dental School, Michael Camilleri, MD Philadelphia, Pennsylvania. Boston, Massachusetts. Professor of Physiology and Medicine, Mayo Clinic College of Medicine, Gilbert J. Fanciullo, MD Antonios Andronikou, PhD Rochester, Minnesota. Associate Professor of Anesthesiology, Executive Director, The Cyprus Anti- Pain Management Center, Dartmouth- Cancer Society, Strovolos, Cyprus. Michael E. Clark, PhD Hitchcock Medical Center, Clinical Director, Chronic Pain Lebanon, New Hampshire. Robert L. Barkin, MBA, PharmD, FCP, Rehabil ita tion Program, James A. DAAPM, Associate Professor, Depart - Haley Veterans Hospital, Kathleen W. Faulkner, MD ments of Anesthesiology, Family Tampa, Florida. Medical Director, Beacon Hospice, Medicine, Pharmacology, and Psychology Boston, Massachusetts Rush University Medical Center, Carol P. Curtiss, RN, MSN Chicago, Illinois. Clinical Nurse Specialist Consultant, John W. Finn, MD, FAAHPM Curtiss Consulting, Chief Medical Director, Hospice of Michigan, David M. Benjamin, PhD, MS Greenfield, Massachusetts. Maggie Allesee Center for Quality of Life, Clinical Pharmacologist and Detroit, Michigan. Toxicologist, Chestnut Hill, Michael R. D’Andrea, PhD Massachusetts. Principal Scientist, Drug Discovery, David A. Fishbain, MD, FAPA Target Validation Team Leader, Professor of Psychiatry, Adjunct Ramsin M. Benyamin, MD, DABPM, Johnson & Johnson Pharmaceutical Professor of Neu rological Surgery and FIPP, President, Millennium Pain R & D, Anesthesiology, University of Miami, Center, Bloomington, Illinois. Spring House, Pennsylvania. Miami, Florida. Jennifer E. Bolen, JD Mellar P. Davis, MD, FCCP Christopher M. Flores, PhD Owner and President, J. Bolen Group, Medical Director, The Harry R. Horvitz Biology Team Leader and Research Fellow, LLC, Center for Palliative Medicine, Analgesics Team, Drug Discovery, Knoxville, Tennessee. Cleveland Clinic Taussig Cancer Center, Johnson & Johnson Pharmaceutical R & D, Cleveland, Ohio. Spring House, Pennsylvania. Eduardo D. Bruera, MD Chairman, Uni versity of Texas MD Franco De Conno, MD, FRCP Sarah Elizabeth Friebert, MD Anderson Cancer Center, Director, National Cancer Institute Director, Akron Children’s Hospital, Houston, Texas. of Milan Division of Rehabilitation, Haslinger Pediatric Palliative Care Division, Milan, Italy. Akron, Ohio. Allen W. Burton, MD Associate Professor and Section John Paul Dobson, PhD, MSc, BSc Frederick J. Goldstein, PhD, FCP Chief of Cancer Pain Manage ment, Professor of Biophysics and Biomedical Professor of Clinical Pharma cology, Coordin - The University of Texas, MD Engineering, Institute of Science ator of Pharmacology, Philadelphia Anderson Cancer Center, and Technology in Med i cine, College of Osteopathic Medicine, Houston, Texas. Stoke-on-Trent, United Kingdom. Philadelphia, Pennsylvania. 12552 4/5/05 Rev. m Jose Antonio Saraiva Ferraz Goncalves, Sandra Hanneken Johnson, JD, LLM Biomedical Ethics, Director, Masters MD, Medical Director, Palliative Care Professor of Law and Tenet Chair in Program in Bioethics, University