DUKE UNIVERSITY MEDICAL CENTER CURRICULUM VITAE Name: Robert McKinnon Califf, M.D., M.A.C.C. Primary academic appointment: Vice Chancellor for Clinical Research Present academic rank and title: Vice Chancellor for Clinical Research Duke University Medical Center Director, Duke Translational Medicine Institute Professor of Medicine, Division of Cardiology Donald F. Fortin Professor, Cardiology Medical licensure: North Carolina License # 26208 Specialty certification: American Board of Internal Medicine 1984 Cardiovascular Diseases 1986 Fellow, American College of Cardiology 1988 Education: Institution Year Degree College: Duke University 1973 BS, Psychology Graduate/ Duke University 1978 MD Professional School Training: University of California, San Francisco 1978 - 1979 Intern, Medicine University of California, San Francisco 1979 - 1980 Assistant Resident, Medicine Duke University Medical Center 1980 - 1983 Fellow, Cardiology Faculty appointments: Associate in Medicine 1982 - 1983 Duke University Medical Center Assistant Professor of Medicine 1983 - 1989 Duke University Medical Center Associate Professor of Medicine 1989 - 1995 Duke University Medical Center Director, Duke Clinical Research Institute 1995 - 2006 Duke University Medical Center Professor of Medicine 1995 - Present Associate Vice Chancellor for Clinical Research 1995 - 2006 Vice Chancellor for Clinical Research 2006 - Present Director, Duke Translational Medicine Institute 2006 - Present PAGE 1 of 114 ROBERT M. CALIFF Duke positions held: Director, CCU 1982 - 1994 Medical Officer – Life Flight 1984 - 1990 Executive Committee of the Medical Staff, Member 1995 - Chair, Committee on Health Information Policy & Services 1995 - 2007 Executive Committee, Duke Medicine (School and Health System) 1995 - Strategy Committee, Duke Health System 1995 - 2004 Chair, Clinical Sciences Faculty Council 1996 - 1998 University Patent Policy Committee 2002 - 2008 Academic Council Trustee Nomination Committee 2002 - 2005 Executive Committee for the Development of the Personalized Health Plan 2003 - 2006 Executive Management Committee of the Health System, Duke University School of Medicine, Member 2004 - Department of Medicine Advisory Board - Senior Advisor 2003 - 2006 University Intellectual Property Board 2003 - 2006 Chancellor’s Academic Cabinet, Member 2005 - Chair – Quality Metrics Committee – Duke Health Systems 2005 - 2006 Academic Leadership Council 2005 - Duke School of Medicine Executive Compliance Committee 2007 - Duke School of Medicine Strategic Funds Committee 2007 - Y.T. and Alice Chen Pediatric Genetics & Genomics Research Center Scientific Advisory Board 2007 - present Duke Heart Center Executive Leadership Committee 2008 - 2010 Co-Chair, Durham Health Innovations Oversight Committee 2008 – David H. Murdock Research Institute, Board Member 2008 Clinical Research Redesign Committee 2009 Professional positions: American Board of Medical Specialties 1999 - American College of Cardiology- Fellow (F.A.C.C) 1988 – 2006 Chair, Merck Fellowship Awards Committee 1990 – 1996 Board of Trustees 2000 - 2005 Task Force on Science and Quality of Care 2000 - 2002 Board of Trustees Working Group on Compensation 2002 - 2004 Annual Self Assessment 2002 - 2003 Quality Strategic Oversight Committee 2002 – 2008 Task Force on Work Force 2003 - 2004 AHA/ Consensus Conference on Ethics 2003 – Quality Strategic Directions Committee 2005 - 2008 Master (M.A.C.C.) 2006 - Young Investigators Award Committee 2006 - 2009 Awards Committee 2007 - 2009 American Heart Association Council on Clinical Cardiology 1995 – Scientific Publishing Committee 2006 -2008 American Heart Journal – Editor-in-Chief 1996 - Donald W Reynolds Foundation Cardiovascular Research Advisory 1997 - 2009 Doris Duke-Scientific Advisory Committee 1998 - 2004 FDA Cardio-Renal Advisory Committee 1996 - 2000 FDA Science Board Working Group 2007 - 2008 National Cancer Inst. Implementation Committee on Clinical Trials 1997 - 1998 National Heart, Lung, and Blood Institute Working Group on Clinical Research 1998 - 2000 Coordinating Center for Education and Research on– PAGE 2 of 114 ROBERT M. CALIFF Therapeutics (CERTs) – PI 1999 – 2007 Center for Education and Research in Therapeutics (CERTs) Vice-Chair of Steering Committee 2007 - 2009 Canadian Heart Research Center Advisory Board 2002 - 2003 Fellow of the European Society of Cardiology 2002 - Medicare Coverage Advisory Committee 2002 - 2003 Institute of Medicine, Clinical Research Roundtable 2003 - 2005 Institute of Medicine Committee on Assessing the Need for Clinical Trials of Testosterone Replacement Therapy 2003 - 2004 Institute of Medicine Committee on Medication Errors 2004 - 2006 Institute of Medicine Forum, Drug Discovery, Development And Translation 2005 - 2006 Center for Information and Study on Clinical Research Participation Board of Advisors 2004 - National Heart, Lung, and Blood Working Group on Hypertension Trials 2004 - 2006 National Library of Medicine Board of Scientific Counselors 2005 - 2009 National Heart, Lung, and Blood Institute Cardiovascular Disease Executive Planning Committee 2006 - 2007 National Heart, Lung, and Blood Institute Working Group On Clinical Trial Design, Co-Chair 2006 - 2007 National Heart, Lung, and Blood Institute Board of External Experts 2007- National Heart, Lung, and Blood Institute Clinical Guidelines Leadership Group for CV Risk Reduction 2007 - 2008 National Heart, Lung and Blood Institute Chairman, Steering committee of the Warfarin Therapy trial 2008 - National Institute of Health – Board of Scientific Counselors 2008 - 2009 National Institute of Health/National Cancer Institute SPORE In Brain Cancer –Internal Advisory Committee 2008 - National Cancer Institute/National Institute of Health Operational Efficiency Working Group (OEWG) 2008 - CTSA Consortium Oversight Steering Committee - Co-Chair 2007 - 2009 Clinical Trials Transformation Initiative (CTTI) - Co-Chair Public-Private Partnership with FDA 2008 - Institute of Medicine Committee on Qualification of Biomarkers and Surrogate Endpoints in Chronic Disease 2009 - National Institute of Environmental Health Science (NIEHS)/NIH - Member, External Clinical Advisory Council 2009 - 2013 CTSA External Advisory Board Membership Columbia University 2008 - UC Davis 2009 - University of Colorado 2009 - University of Chicago 2009 Clinical Research Forum – Chairman 2010 - 2013 NIH-National Advisory Council on Aging 2010 – 2013 American Orthopaedic Association Institute of Medicine Taskforce On Ethics 2010 HHS – Secretary’s Advisory Council on Human Research Protections (SACHRP) – Subcommittee on Harmonization 2010 - 2011 Society for Clinical and Translational Sciences – Board of Directors 2009 – 2013 Office of the Speaker, NC House of Representatives Comparative Effectiveness Study Committee Advisory Board 2010 - 2011 Journal reviewer: Current American Heart Journal PAGE 3 of 114 ROBERT M. CALIFF American Journal of Cardiology Annals of Internal Medicine Cardiosource Clinical Trials Circulation European Heart Journal Heart Lung and Circulation Journal of the American College of Cardiology Journal of the American Medical Association Journal of Invasive Cardiology Lancet New England Journal of Medicine American Journal of Kidney Disease American Journal of Medicine Archives of Internal Medicine Canadian Journal of Cardiology Chest Journal of Clinical Epidemiology Journal of General Internal Medicine Thrombosis and Hemostasis Health Affairs Editorial boards: Current American Heart Journal Cardiosource Clinical Trials Circulation Clinical Trials, The Journal of the Society for Clinical Trials European Heart Journal Heart Lung and Circulation Science Translational Medicine (Advisory Board) Past American Journal of Cardiology Current Treatment Options in Cardiovascular Diseases Journal of Interventional Cardiology Journal of the American College of Cardiology Consultancy: Health Services Research & Development 1984 - Present Veterans Administration Donald W. Reynolds Foundation Scientific Advisory Panel Cardiovascular Research 1998 Honors and awards: Phi Beta Kappa 1973 Duke University Alpha Omega Alpha 1976 Duke University Medical School President, Senior Class 1978 Duke University Medical School Lange Book Award 1978 PAGE 4 of 114 ROBERT M. CALIFF Duke University Medical School Distinguished Resident Teaching Award 1981 University of California at San Francisco School of Medicine Donald F. Fortin Professor, Cardiology 1995 Distinguished Scientist Award for Clinical Research 2004 American College of Cardiology Master of the American College of Cardiology 2006 2006 Clinical Research Award 2006 American Heart Association Duke Distinguished Alumni Faculty Award 2006 AHA Distinguished Scientist Award 2009 Memberships Current American College of Cardiology American College of Physicians American Medical Association American Society of Clinical Investigation Argentine Society of Cardiology Association of American Physicians Drug Information Association Society for Clinical Epidemiology and Health Care Research American Heart Association Association of University Cardiologists European Society of Cardiology Association of American Physicians American Society of Clinical Investigators Society for Clinical Trials, Inc. Selected Recent Invited Lectures: 1998 Dallas, TX, Baylor University Medical Center Visiting Professor, presentation, “Do We Need Academic Cardiologists?” Birmingham, AL, University of Alabama School of Medicine Visiting Professor 1999 Stanford, CA, Stanford University School